Franciscan Sisters of Perpetual Adoration

Viterbo University is a private Catholic university in La Crosse, Wisconsin. Founded in 1890 by the Franciscan Sisters of Perpetual Adoration, Viterbo is home to three colleges with nine schools offering 48 academic programs at the associate, bachelor's, master's, and doctoral levels.Viterbo is one of 23 Franciscan universities in the United States, with 2,521 undergraduate and graduate students and over 23,000 alumni. As of 2020, Viterbo's endowment was a record $55.7 million. Viterbo is a member of the NAIA and the North Star Athletic Association; its athletic teams are known as the V-Hawks.

St. Rose of Viterbo Convent is the motherhouse of the Franciscan Sisters of Perpetual Adoration, an American religious congregation, which is located in La Crosse, Wisconsin. The convent is dedicated to Rose of Viterbo, a 13th-century Franciscan tertiary who was a noted mystic and street preacher in Italy who died while still a teenager.The convent contains three chapels, of which one, Mary of the Angels Chapel, is listed on the National Register of Historic Places of the United States. Another, the Adoration Chapel, is the site of perpetual adoration of the Blessed Sacrament, was the site of 141 years of uninterrupted practice of the Sisters from August 1, 1878 to February 2020. The sisters continue to pray in shifts between 6 a.m. and 10 p.m.

The Mons Anderson House is a historic house located at 410 Cass Street in La Crosse, Wisconsin.

The World's Largest Six-Pack is a large collection of six beer storage tanks in La Crosse, Wisconsin. It is a well-known landmark and tourist attraction in the city. The cans can collectively hold about 688,200 US gal (2,605,000 L) of beer.

The Cathedral of St. Joseph the Workman is the mother church of the Diocese of La Crosse. The cathedral, designed by architect Edward J. Schulte, was completed in 1962. Built of limestone, it has a tall clock tower which rises above the surrounding buildings in downtown La Crosse, Wisconsin.In 2008, the cathedral undertook a six-week project to repair the steeple. In March 2021, the cathedral began another program to repair the steeple which began to drop stones in summer 2020. The renovations will address several problem areas of the structure and are expected to be complete by year's end.The following Bishops of the Diocese of La Crosse are buried in the Blessed Sacrament Chapel: Kilian Caspar Flasch James Schwebach Alexander Joseph McGavick, founder of Aquinas High School-La Crosse, Wisconsin John Patrick Treacy, the builder of the new cathedral Frederick William Freking John Joseph PaulNote:Bishop Michael Heiss is buried in Milwaukee and Auxiliary Bishop William Richard Griffin is buried in Chicago.

Mayo Clinic Health System - Franciscan Healthcare is one of the two hospitals in La Crosse, Wisconsin. Franciscan Healthcare is part of the Mayo Clinic Health System This hospital has 142 beds and provides emergency services and an Intensive Care Unit.

City Brewing Company is a large brewery located in La Crosse, Wisconsin, USA. It also goes by the trade name of City Brewery.

La Crosse Public Library (La Crosse, Wisconsin) is the public library system in La Crosse, Wisconsin. The library serves as the resource library for the Winding Rivers Library System and the administrative offices for WRLS are at the public library. The library serves 50,000 people, has 245,000 volumes, and has 800,000 annual circulation transactions.In 2005, the La Crosse Public Library won an award for its digitized history website.

Christ Episcopal Church is a historic Episcopal church located in La Crosse, Wisconsin in the Episcopal Diocese of Eau Claire. In 1985, Christ Church was added to the National Register of Historic Places.

The La Crosse Commercial Historic District is located in downtown La Crosse, Wisconsin. It includes over ninety contributing structures, mostly 2-3 story commercial brick buildings constructed from the 1860s to the 1940s. The district is roughly bounded by Jay Street, Second Street South, State Street, and Fifth Avenue South.Some of the notable contributing properties include the 1866 Voegle grocery and saloon, the 1870 Italianate Solberg grocery store, the 1894 Romanesque/Queen Anne Rehfuss dry goods building, the 1903 Chicago school Doerflinger department store, the 1920 Neoclassical Rivoli building and theatre, and the 1940 Moderne Hoeschler Exchange building.The district currently contains numerous bars and restaurants. Downtown La Crosse once had the Guinness Book record with the most bars/nightclubs located on one street, which was Third Street. The area also includes other shops, offices, and residential spaces. The NRHP listed Freight House is located two blocks north of the historic district.

Aquinas High School is a Roman Catholic high school located in La Crosse, Wisconsin. The school is part of La Crosse Aquinas Catholic Schools and is operated by the Diocese of La Crosse. In 2008, Aquinas High School was named a national Blue Ribbon School.

Gundersen Health System (Gundersen Health) is a comprehensive non-profit health system based in La Crosse, Wisconsin. The system includes multi-specialty group medical practices, a teaching hospital, regional community clinics, affiliate hospitals and clinics, behavioral health services, vision centers, pharmacies, and air and ground ambulances.Gundersen Health's flagship hospital, Gundersen Lutheran Medical Center, is located in La Crosse and is a teaching hospital with 325 beds and a Level II Trauma and Emergency Center. The hospital received Healthgrades America's 50 Best Hospitals recognition in 2015 and 2017 placing it in the top 1% nationally. Additional awards include receiving the Healthgrades Distinguished Hospital Award-Clinical Excellence recognition eight years in a row from 2008 to 2015.Gundersen Lutheran is also a designated academic campus for the University of Wisconsin School of Medicine and Public Health.