Washington Street United Methodist Church

The Owen Building, known more recently as the Bruce Building, is a historic office building at 1321 Lady Street in Columbia, South Carolina. It is an eight-story concrete structure which was built in 1949 around the core of an older two-story brick building. It was designed by Lafaye, Lafaye, and Fair for local businessman Frank Owen, and was the first skyscraper built in the city after World War II. Its primary tenant for many years was Southern Bell Telephone Company, who in 1961 constructed an annex to the building to house computer equipment. It was purchased by the Seibels Bruce Insurance Company, another major tenant, in 1980. The building exterior has been relatively little-altered since its construction, and it retains some of its early internal features, including a period mail chute.The building was listed on the National Register of Historic Places in 2013.

The First Presbyterian Church is a historic church building in Columbia, South Carolina. Constructed in 1854, it was added to the National Register of Historic Places on January 25, 1971.

Tunnelvision is a 50 ft x 75 ft large trompe-l'œil painting, by Blue Sky, on a building in Columbia, South Carolina, USA, which shows a tunnel in original size. Tunnelvision looks very realistic.

The James Petigru Boyce Chapel is a historic church building at 1306 Hampton Street in Columbia, South Carolina. It is a Greek Revival building built in 1859. A convention met here on December 17, 1860, whose delegates voted unanimously for South Carolina to secede from the United States, leading to the American Civil War. It was designated a National Historic Landmark as First Baptist Church, the role it played at the time. The building is part of the facilities complex of the First Baptist Church, Columbia- a Southern Baptist megachurch.

Prisma Health Baptist Hospital (Formerly Baptist Medical Center and Palmetto Health Baptist Columbia) is a 489-bed acute-care facility located at the intersection of Taylor and Marion Streets in Downtown Columbia, South Carolina. The hospital was established in 1914 as South Carolina Baptist Hospital by the South Carolina Baptist Convention after the widow of Dr. Augustus B. Knowlton, a prominent Columbia physician, asked the church to purchase the hospital, at that time a 70-bed facility on Marion St., that she and her husband started. Over the years, the hospital expanded and grew as additional services were offered. Baptist Columbia became part of the Baptist Healthcare System when a second Baptist hospital was built in Easley, South Carolina in 1958. In 1998, the two-hospital Baptist Healthcare System merged with Richland Memorial Hospital to form Palmetto Health, the largest healthcare system in South Carolina at the time. In 2017, Palmetto Health merged with the Greenville Hospital System to form Prisma Health and continues as the largest not-for profit hospital operator in South Carolina.

The Church of the Apostles is an evangelical Anglican church in downtown Columbia, South Carolina. Founded in 2003 as part of the Anglican realignment, it serves today as the cathedral parish for the Diocese of the Carolinas.

The Federal Land Bank Building, built in 1924, is a bank in Columbia, South Carolina. It was designed by architect A. Ten Eyck Brown. The Federal Land Bank Building was listed on the National Register of Historic Places in 2015.Construction began in 1923 and was completed in 1924. The building was added on to in 1935.

The Carolina Life Insurance Company is a historic commercial building at 1501 Lady Street in Columbia, South Carolina, alternatively known as Seibels, Bruce & Company Building. It is a five-story masonry structure, finished primarily in limestone with granite trim. It presents an angled five-bay facade to the junction of Lady and Bull Streets, and is presently known as the Seibels Building. It was built in 1949 and enlarged in 1977; its original design by the local firm of Lafaye, Lafaye & Fair was a major contribution to the city's modern architecture. The Carolina Life Insurance Company only occupied the building until the early 1960s, when it was merged into another insurance company. It has since 1965 been home to Seibels, Bruce & Company, another insurer.The building was added to the National Register of Historic Places in 2016.

Tower at 1301 Gervais is a high-rise office building in Columbia, South Carolina, and the tallest building in the city not located along the Main Street corridor. Built in 1973, the tower has dark glazing with anodized aluminum columns to give it a dark, uniform-colored appearance. The top floor of the tower holds a private club with views of the city. It was originally constructed for Bankers Trust as their headquarters. It was the tallest building in the city at its completion until the Palmetto Center was topped out on January 23, 1983. In 2020, the Tower at 1301 Gervais was identified as having an employer who employed an individual who tested positive for Covid-19.

Bethel A.M.E. Church is a historic African Methodist Episcopal Church at 1528 Sumter Street in Columbia, South Carolina.It was built in 1921 and added to the National Register in 1982.

The Zimmerman House is a historic home located at Columbia, South Carolina, United States. It was built in 1848, and consists of a 1+1⁄2-story main section and a one-story wing. The front façade features a Greek Revival style pedimented portico supported by two paneled wooden square columns. The house was built by Charles and Hannah Zimmerman, who operated the neighboring Zimmerman School from 1848 to 1870.It was added to the National Register of Historic Places in 1979.

The Columbia Commercial Historic District encompasses a historically significant portion of the central business district of Columbia, South Carolina. It includes portions of three blocks of Main Street between Laurel and Hampton Streets, as well as individual buildings on adjacent streets. It includes the full length of Main Streets east side on these blocks, but only the central block (between Blanding and Taylor Streets) on the west side, extending slightly south of Taylor. This area best illustrates the city's commercial and economic growth for a century, from the end of the American Civil War to about 1963, with a broad diversity of architectural styles found in a small area.The district was added to the National Register of Historic Places in 2014, and has twice been enlarged. Nine of the district's 36 buildings are also individually listed.