Smallpox Hospital

Strecker Memorial Laboratory is a historic building located in Southpoint Park on Roosevelt Island in New York City. Built in 1892 to serve as a laboratory for City Hospital, it was "the first institution in the nation for pathological and bacteriological research". The project was funded by the Strecker family. The building was designed by architects Frederick Clarke Withers and Walter Dickson in the Romanesque Revival style with large arched windows to provide plenty of natural lighting and ventilation. On the first floor were an autopsy room and an office, while the floor above housed laboratories where specimens were examined. The cellar was used as a mortuary and for storage. Administrative support was provided by the nearby City Hospital. An additional storey was later built, providing room for the examination of histological samples, a scientific library and a pathology museum.In 1907, the Russell Sage Institute of Pathology took over the running of the lab. In time, this became associated with the Rockefeller University, and work continued at the laboratory until it closed in the 1950s, after which it fell into disrepair.In 1972, it was added to the National Register of Historic Places, and in 1976 it was designated a New York City landmark. The Metropolitan Transportation Authority decided to use the structure to house a power conversion substation for the subway trains that run through the 53rd Street Tunnel underneath Roosevelt Island. The city faithfully restored the building, and the substation has been active since 2000.

City Hospital (also known as Island Hospital or Charity Hospital) was an historic hospital on Roosevelt Island, Manhattan in New York City.

The Franklin D. Roosevelt Four Freedoms Park is a four-acre (1.6 ha) memorial to Franklin D. Roosevelt that celebrates the Four Freedoms he articulated in his 1941 State of the Union address. It is located adjacent to the historic Smallpox Hospital in New York City at the southernmost point of Roosevelt Island, in the East River between Manhattan Island and Queens. It was originally designed by the architect Louis Kahn in 1974, but funds were only secured for groundbreaking in 2010 and completion in 2012.

Anable Basin (also known as Eleventh Street Basin) is a 500-foot-long (150 m) artificial inlet of the East River located in the Long Island City neighborhood of Queens, New York City. It was carved in 1868 to serve the large concentrations of industrial firms in the neighborhood. A public walkway along the southwest side of the basin was constructed as part of the Queens West development in 2012. The basin contains several private vessels, the former Water's Edge restaurant, a former Prudence Island ferry boat, and a floating dock owned by Long Island City Community Boathouse, used for its kayaking programs. In November 2018 it was announced that Amazon would be building its large Amazon HQ2 campus on the land surrounding the basin. However, these plans have since been canceled.

The Pepsi-Cola sign is a neon sign at Gantry Plaza State Park in the Long Island City neighborhood of Queens in New York City. The sign, visible from Manhattan and the East River, was built in 1940 and originally installed atop PepsiCo (previously Pepsi-Cola)'s bottling factory nearby. It is composed of a 50-foot (15 m) depiction of a Pepsi bottle, as well as lettering that reflected PepsiCo's logo when the sign was commissioned. The Pepsi-Cola sign was likely manufactured by the General Outdoor Advertising Company and was New York state's longest electric sign when completed. The bottle depiction was replaced in the 1970s, and Artkraft Strauss Sign Corporation rebuilt the rundown sign in 1993. When the Pepsi facility was closed in 2003, the sign was relocated to the park. The New York City Landmarks Preservation Commission began holding hearings on whether to make the sign a city landmark in 1988, though it was not designated as such until 2016.

Water's Edge was a restaurant on barges moored in the East River on the Long Island City waterfront in Queens, New York that operated from 1983 to 2015. Located at the foot of 44th Drive between Anable Basin and the Queensboro Bridge, the restaurant had a panoramic view of the Midtown Manhattan skyline and was a popular wedding venue.

River House is a co-op apartment building located at 435 East 52nd Street in Manhattan, New York City.

Peter Detmold Park is a 0.59-acre (0.24 ha) public park in the Turtle Bay neighborhood of Manhattan, New York, United States. Located on a narrow strip of land on the west side of the FDR Drive, the park runs from East 49th to 51st streets and was originally developed as a result of the construction of the adjacent highway in the early 1940s. The park was named after Peter Detmold in 1972 and can be accessed from a staircase leading down from the east end of East 51st Street or a street-level entrance on East 49th Street across from MacArthur Playground.

Cornell Tech is a technology, business, law, and design campus of Cornell University located on Roosevelt Island in Manhattan, New York City. It includes the Jacobs Technion-Cornell Institute, a joint academic venture between Cornell and the Technion – Israel Institute of Technology. Cornell Tech arose from an economic development initiative of Michael Bloomberg's mayoral administration in 2008. The initiative sought to attract another engineering school to the city in the hope that it would produce entrepreneurial engineers who would in turn start job-creating companies. Seven bids were submitted for the competition, with the administration ultimately selecting Cornell/Technion's bid. As proposed, Cornell Tech would create 28,000 jobs, including 8,000 for academic staff. It would also be able to create 600 companies, leading to $23 billion in economic benefits and an additional $1.4 billion in taxes, during its first three decades of operation. Cornell Tech began operations in 2012 at a temporary site, the New York City offices of Google at 111 Eighth Avenue in the Chelsea neighborhood of Manhattan, while a permanent campus was under construction. The Roosevelt Island campus's 5-acre (2.0 ha) first phase opened on September 13, 2017. By 2037, the full campus is expected to span 12 acres (4.9 ha).

One Sutton Place South is a 14-story, 42-unit cooperative apartment house in the East Midtown neighborhood of Manhattan, New York City, overlooking the East River on Sutton Place between 56th and 57th Streets. One Sutton Place South contains the residences of diplomats, titans of industry, and media executives.

23 Beekman Place, also the Paul Rudolph Apartment & Penthouse, is an apartment building between 50th and 51st streets in the Turtle Bay neighborhood of Manhattan in New York City. Built c. 1869 as a five-story brownstone residence, it was substantially redesigned in the late 20th century by Paul Rudolph, an American architect and one-time dean of Yale University. It is one of the few known projects Rudolph designed in the city. The house is part of a secluded residential enclave surrounding Beekman Place. It consists of the original brownstone residence, along with a four-story steel skeletal penthouse with concrete wall panels, which is cantilevered slightly over the street. The rear walls contain full-width windows with East River views, while the interiors contain high ceilings and open floor plans. Throughout his occupancy at the building, from the 1960s to 1990s, Rudolph constantly adjusted the interior layout. The penthouse originally received negative feedback from neighbors, who expressed concerns that it would draw excessive attention to the area and that it would block their own views of the river. The building was originally a brownstone along with the other structures in the area. In the first half of the 20th century, it was occupied by actress Katharine Cornell and director and producer Guthrie McClintic, who were married. Starting in 1961, Rudolph leased a fourth-story apartment at 23 Beekman Place, and he ultimately bought the entire building outright in 1976. Following that, Rudolph redeveloped the building from 1977 to 1982, constructing the steel penthouse above the existing masonry apartments. After Rudolph died in 1997, the building was sold to the Boyd family and then to Steven Campus, who both renovated the interior. The New York City Landmarks Preservation Commission designated the house as a landmark in 2010.

Luxembourg House is a historic mansion located at 17 Beekman Place, Midtown Manhattan, New York City, owned by the Grand Duchy of Luxembourg. It is home to the Permanent Mission of Luxembourg to the United Nations, the Consulate General of Luxembourg in New York, the Luxembourg Trade and Investment Office and the activities of the Luxembourg-American Chamber of Commerce. It hosts a number of international relations, international trade and cultural activities for the European country of Luxembourg. The property is territory of the country of Luxembourg providing it all diplomatic rights and privileges.