Franklin D. Roosevelt Four Freedoms Park

The Smallpox Hospital, sometimes referred to as the Renwick Smallpox Hospital and later the Maternity and Charity Hospital Training School, was a hospital located on Roosevelt Island in Manhattan, New York City. Originally designed by architect James Renwick Jr., the 100-bed hospital opened in 1856, when the area was known as Blackwell's Island.A century after it opened, the hospital was closed, and the building eventually fell into disrepair. It was listed on the National Register of Historic Places in 1972 and designated a New York City Landmark four years later, the only ruin in the city with that designation. After the completion of an ongoing $4.5 million stabilization project, the Smallpox Hospital ruins will be open to the public.

Strecker Memorial Laboratory is a historic building located in Southpoint Park on Roosevelt Island in New York City. Built in 1892 to serve as a laboratory for City Hospital, it was "the first institution in the nation for pathological and bacteriological research". The project was funded by the Strecker family. The building was designed by architects Frederick Clarke Withers and Walter Dickson in the Romanesque Revival style with large arched windows to provide plenty of natural lighting and ventilation. On the first floor were an autopsy room and an office, while the floor above housed laboratories where specimens were examined. The cellar was used as a mortuary and for storage. Administrative support was provided by the nearby City Hospital. An additional storey was later built, providing room for the examination of histological samples, a scientific library and a pathology museum.In 1907, the Russell Sage Institute of Pathology took over the running of the lab. In time, this became associated with the Rockefeller University, and work continued at the laboratory until it closed in the 1950s, after which it fell into disrepair.In 1972, it was added to the National Register of Historic Places, and in 1976 it was designated a New York City landmark. The Metropolitan Transportation Authority decided to use the structure to house a power conversion substation for the subway trains that run through the 53rd Street Tunnel underneath Roosevelt Island. The city faithfully restored the building, and the substation has been active since 2000.

The Pepsi-Cola sign is a neon sign at Gantry Plaza State Park in the Long Island City neighborhood of Queens in New York City. The sign, visible from Manhattan and the East River, was built in 1940 and originally installed atop PepsiCo (previously Pepsi-Cola)'s bottling factory nearby. It is composed of a 50-foot (15 m) depiction of a Pepsi bottle, as well as lettering that reflected PepsiCo's logo when the sign was commissioned. The Pepsi-Cola sign was likely manufactured by the General Outdoor Advertising Company and was New York state's longest electric sign when completed. The bottle depiction was replaced in the 1970s, and Artkraft Strauss Sign Corporation rebuilt the rundown sign in 1993. When the Pepsi facility was closed in 2003, the sign was relocated to the park. The New York City Landmarks Preservation Commission began holding hearings on whether to make the sign a city landmark in 1988, though it was not designated as such until 2016.

U Thant Island (officially Belmont Island) is a small artificial island or islet in the borough of Manhattan in New York City. The 100-by-200-foot (30 by 60 m) island, created during the construction of the Steinway Tunnel directly underneath, is the smallest island in Manhattan.

Peter Detmold Park is a 0.59-acre (0.24 ha) public park in the Turtle Bay neighborhood of Manhattan, New York, United States. Located on a narrow strip of land on the west side of the FDR Drive, the park runs from East 49th to 51st streets and was originally developed as a result of the construction of the adjacent highway in the early 1940s. The park was named after Peter Detmold in 1972 and can be accessed from a staircase leading down from the east end of East 51st Street or a street-level entrance on East 49th Street across from MacArthur Playground.

City Hospital (also known as Island Hospital or Charity Hospital) was an historic hospital on Roosevelt Island, Manhattan in New York City.

MacArthur Playground, officially named General Douglas MacArthur Memorial Park, is a 0.33-acre (0.13 ha) public park in the Turtle Bay neighborhood of Manhattan, New York, United States. The park is located on the east end of the block bounded by First Avenue, General Douglas MacArthur Plaza, and East 48th and 49th streets, immediately to the north of the Headquarters of the United Nations. The park and plaza, the latter of which is a north–south street that runs for a single block between the playground and the FDR Drive, were named after Douglas MacArthur in October 1964. The park was donated to the city by Alcoa Plaza Associates, the developer of the adjacent mixed-use building at 860-870 United Nations Plaza.

Luxembourg House is a historic mansion located at 17 Beekman Place, Midtown Manhattan, New York City, owned by the Grand Duchy of Luxembourg. It is home to the Permanent Mission of Luxembourg to the United Nations, the Consulate General of Luxembourg in New York, the Luxembourg Trade and Investment Office and the activities of the Luxembourg-American Chamber of Commerce. It hosts a number of international relations, international trade and cultural activities for the European country of Luxembourg. The property is territory of the country of Luxembourg providing it all diplomatic rights and privileges.

23 Beekman Place, also the Paul Rudolph Apartment & Penthouse, is an apartment building between 50th and 51st streets in the Turtle Bay neighborhood of Manhattan in New York City. Built c. 1869 as a five-story brownstone residence, it was substantially redesigned in the late 20th century by Paul Rudolph, an American architect and one-time dean of Yale University. It is one of the few known projects Rudolph designed in the city. The house is part of a secluded residential enclave surrounding Beekman Place. It consists of the original brownstone residence, along with a four-story steel skeletal penthouse with concrete wall panels, which is cantilevered slightly over the street. The rear walls contain full-width windows with East River views, while the interiors contain high ceilings and open floor plans. Throughout his occupancy at the building, from the 1960s to 1990s, Rudolph constantly adjusted the interior layout. The penthouse originally received negative feedback from neighbors, who expressed concerns that it would draw excessive attention to the area and that it would block their own views of the river. The building was originally a brownstone along with the other structures in the area. In the first half of the 20th century, it was occupied by actress Katharine Cornell and director and producer Guthrie McClintic, who were married. Starting in 1961, Rudolph leased a fourth-story apartment at 23 Beekman Place, and he ultimately bought the entire building outright in 1976. Following that, Rudolph redeveloped the building from 1977 to 1982, constructing the steel penthouse above the existing masonry apartments. After Rudolph died in 1997, the building was sold to the Boyd family and then to Steven Campus, who both renovated the interior. The New York City Landmarks Preservation Commission designated the house as a landmark in 2010.

Gantry Plaza State Park is a 12-acre (4.9 ha) state park on the East River in the Hunters Point section of Long Island City, in the New York City borough of Queens. The park is located in a former dockyard and manufacturing district, and includes remnants of facilities from the area's past. The most prominent feature of the park is a collection of gantries with car float transfer bridges, which in turn were served by barges that carried freight railcars between Queens and Manhattan.

Queens West is a district and redevelopment project along the East River in Long Island City, Queens, New York City. The project, located on Hunter's Point south of the Anable Basin, is a joint project sponsored by the Port Authority of New York & New Jersey (PANYNJ) and the Empire State Development Corporation (ESD). The Queens West Development Corporation (QWDC), a subsidiary of ESD, was established in 1992 to facilitate implementation of the approved development plan.

River House is a co-op apartment building located at 435 East 52nd Street in Manhattan, New York City.