City Hospital (Roosevelt Island)

Strecker Memorial Laboratory is a historic building located in Southpoint Park on Roosevelt Island in New York City. Built in 1892 to serve as a laboratory for City Hospital, it was "the first institution in the nation for pathological and bacteriological research". The project was funded by the Strecker family. The building was designed by architects Frederick Clarke Withers and Walter Dickson in the Romanesque Revival style with large arched windows to provide plenty of natural lighting and ventilation. On the first floor were an autopsy room and an office, while the floor above housed laboratories where specimens were examined. The cellar was used as a mortuary and for storage. Administrative support was provided by the nearby City Hospital. An additional storey was later built, providing room for the examination of histological samples, a scientific library and a pathology museum.In 1907, the Russell Sage Institute of Pathology took over the running of the lab. In time, this became associated with the Rockefeller University, and work continued at the laboratory until it closed in the 1950s, after which it fell into disrepair.In 1972, it was added to the National Register of Historic Places, and in 1976 it was designated a New York City landmark. The Metropolitan Transportation Authority decided to use the structure to house a power conversion substation for the subway trains that run through the 53rd Street Tunnel underneath Roosevelt Island. The city faithfully restored the building, and the substation has been active since 2000.

The Smallpox Hospital, sometimes referred to as the Renwick Smallpox Hospital and later the Maternity and Charity Hospital Training School, was a hospital located on Roosevelt Island in Manhattan, New York City. Originally designed by architect James Renwick Jr., the 100-bed hospital opened in 1856, when the area was known as Blackwell's Island.A century after it opened, the hospital was closed, and the building eventually fell into disrepair. It was listed on the National Register of Historic Places in 1972 and designated a New York City Landmark four years later, the only ruin in the city with that designation. After the completion of an ongoing $4.5 million stabilization project, the Smallpox Hospital ruins will be open to the public.

Cornell Tech is a technology, business, law, and design campus of Cornell University located on Roosevelt Island in Manhattan, New York City. It includes the Jacobs Technion-Cornell Institute, a joint academic venture between Cornell and the Technion – Israel Institute of Technology. Cornell Tech arose from an economic development initiative of Michael Bloomberg's mayoral administration in 2008. The initiative sought to attract another engineering school to the city in the hope that it would produce entrepreneurial engineers who would in turn start job-creating companies. Seven bids were submitted for the competition, with the administration ultimately selecting Cornell/Technion's bid. As proposed, Cornell Tech would create 28,000 jobs, including 8,000 for academic staff. It would also be able to create 600 companies, leading to $23 billion in economic benefits and an additional $1.4 billion in taxes, during its first three decades of operation. Cornell Tech began operations in 2012 at a temporary site, the New York City offices of Google at 111 Eighth Avenue in the Chelsea neighborhood of Manhattan, while a permanent campus was under construction. The Roosevelt Island campus's 5-acre (2.0 ha) first phase opened on September 13, 2017. By 2037, the full campus is expected to span 12 acres (4.9 ha).

The Delacorte Fountain, also known as the Delacorte Geyser, was a large fountain located near the southern tip of Roosevelt Island in New York City. Dedicated in 1969, the fountain operated from 1970 until 1986 when it last broke down and was abandoned. The remains of the former fountain, including the building that housed its equipment, were demolished in 1994. The former site of the fountain is now occupied by Franklin D. Roosevelt Four Freedoms Park.

One Sutton Place South is a 14-story, 42-unit cooperative apartment house in the East Midtown neighborhood of Manhattan, New York City, overlooking the East River on Sutton Place between 56th and 57th Streets. One Sutton Place South contains the residences of diplomats, titans of industry, and media executives.

The Franklin D. Roosevelt Four Freedoms Park is a four-acre (1.6 ha) memorial to Franklin D. Roosevelt that celebrates the Four Freedoms he articulated in his 1941 State of the Union address. It is located adjacent to the historic Smallpox Hospital in New York City at the southernmost point of Roosevelt Island, in the East River between Manhattan Island and Queens. It was originally designed by the architect Louis Kahn in 1974, but funds were only secured for groundbreaking in 2010 and completion in 2012.

River House is a co-op apartment building located at 435 East 52nd Street in Manhattan, New York City.

Water's Edge was a restaurant on barges moored in the East River on the Long Island City waterfront in Queens, New York that operated from 1983 to 2015. Located at the foot of 44th Drive between Anable Basin and the Queensboro Bridge, the restaurant had a panoramic view of the Midtown Manhattan skyline and was a popular wedding venue.

Anable Basin (also known as Eleventh Street Basin) is a 500-foot-long (150 m) artificial inlet of the East River located in the Long Island City neighborhood of Queens, New York City. It was carved in 1868 to serve the large concentrations of industrial firms in the neighborhood. A public walkway along the southwest side of the basin was constructed as part of the Queens West development in 2012. The basin contains several private vessels, the former Water's Edge restaurant, a former Prudence Island ferry boat, and a floating dock owned by Long Island City Community Boathouse, used for its kayaking programs. In November 2018 it was announced that Amazon would be building its large Amazon HQ2 campus on the land surrounding the basin. However, these plans have since been canceled.

York Avenue, Sutton Place, and Sutton Place South are the names of segments of a north–south thoroughfare in the Yorkville, Lenox Hill, and Sutton Place neighborhoods of the East Side of Manhattan, in New York City. York Avenue runs from 59th to 92nd Streets through eastern Lenox Hill and Yorkville on the Upper East Side. Sutton Place and Sutton Place South run through their namesake neighborhood along the East River and south of the Queensboro Bridge. Sutton Place South runs from 57th to 53rd Streets. Unlike most north–south streets in Manhattan, building address numbers along Sutton Place South increase when headed south. Sutton Place runs from 57th to 59th Streets. The streets are considered among the city's most affluent, and both portions are known for upscale apartments, much like the rest of the Upper East Side. Addresses on York Avenue are continuous with that of Avenue A in the Alphabet City neighborhood, starting in the 1100 series and rising to the 1700 series. Addresses on Sutton Place and Sutton Place South do not follow the usual pattern in Manhattan. The greater Sutton Place neighborhood, which sits north of the neighborhood of Turtle Bay, runs from 53rd Street to 59th Street and is bounded on the east by the East River and on the west by either First Avenue or Second Avenue. Sutton Square is the cul-de-sac at the end of East 58th Street, just east of Sutton Place; Riverview Terrace is a row of townhouses on a short private driveway that runs north from Sutton Square.

Le Club was a members-only restaurant and nightclub located at 416 East 55th Street in Manhattan. French expatriate Olivier Coquelin founded Le Club in 1960.It was a playground for New York's elites, including the Vanderbilts and Kennedys. As a young man in the 1970s, Donald Trump frequented the club, particularly associating with Roy Cohn.

The Queensboro Bridge, officially named the Ed Koch Queensboro Bridge, is a cantilever bridge over the East River in New York City. Completed in 1909, it connects the neighborhood of Long Island City in the borough of Queens with the Upper East Side in Manhattan, passing over Roosevelt Island. The bridge is also known as the 59th Street Bridge because its Manhattan end is located between 59th and 60th streets. The Queensboro Bridge carries New York State Route 25 (NY 25), which terminates at the bridge's western end in Manhattan, and also once carried NY 24 and NY 25A. The western leg of the Queensboro Bridge is flanked on its northern side by the freestanding Roosevelt Island Tramway. The bridge was, for a long time, simply called the Queensboro Bridge, but in March 2011, the bridge was officially renamed in honor of former New York City mayor Ed Koch. The Queensboro Bridge is the northernmost of four toll-free vehicular bridges connecting Manhattan Island to Long Island, along with the Williamsburg, Manhattan, and Brooklyn bridges to the south. It is the first entry point into Manhattan in the course of the New York City Marathon and the last exit point out of Manhattan in the Five Boro Bike Tour.