Greyhound Bus Depot (Columbia, South Carolina)

The Building at 1644 Main Street, also known as Tapp's Department Store, is a historic commercial building located at Columbia, South Carolina. It was built in 1940, and enlarged in 1950. It is a five- to seven-story, Depression Modern building faced in stucco and dark tremolite stone. Above the main entrance is a distinctive clock face and a sign with large freestanding letters. Tapp's Department Store closed in 1995. It was added to the National Register of Historic Places in 1979.

Ladson Presbyterian Church is a historic African American Presbyterian church located at 1720 Sumter Street in Columbia, South Carolina. The religious building was initially a chapel founded in 1838 and, rebuilt in 1896, and is a one-story-over-raised-basement, rectangular red brick building in the Renaissance Revival style. It has a front gable roof and features two brick entrance towers. The congregation was founded in 1838, as an offshoot congregation of the First Presbyterian Church.It was added to the National Register of Historic Places in 1998.

The Bouchier Building is a historic commercial building located in Columbia, South Carolina. It was built in 1913–14, and is a three-story, terra cotta faced building with large areas of glass on the upper floors.It was added to the National Register of Historic Places as the Building at 1722–1724 Main Street in 1979.

Efird's Department Store, also known as Lourie's Department Store, is a historic department store building located at Columbia, South Carolina. It was built about 1870, and is a rectangular brick building renovated and expanded in 1919. This included the addition of a third story and the installation of a new brick façade and store entrances. Between 1919 and 1958, it housed the Columbia branch of the Charlotte, North Carolina based Efird's Department Store chain. It currently houses a Mast General Store, which moved in on May 25, 2011. It was added to the National Register of Historic Places in 2012.

The Columbia Commercial Historic District encompasses a historically significant portion of the central business district of Columbia, South Carolina. It includes portions of three blocks of Main Street between Laurel and Hampton Streets, as well as individual buildings on adjacent streets. It includes the full length of Main Streets east side on these blocks, but only the central block (between Blanding and Taylor Streets) on the west side, extending slightly south of Taylor. This area best illustrates the city's commercial and economic growth for a century, from the end of the American Civil War to about 1963, with a broad diversity of architectural styles found in a small area.The district was added to the National Register of Historic Places in 2014, and has twice been enlarged. Nine of the district's 36 buildings are also individually listed.

Lever Building is a historic commercial building located at Columbia, South Carolina. It was built in 1903, and is a three-story building faced with brown brick and terra cotta.It was added to the National Register of Historic Places in 1979.

Bethel A.M.E. Church is a historic African Methodist Episcopal Church at 1528 Sumter Street in Columbia, South Carolina.It was built in 1921 and added to the National Register in 1982.

The Columbia City Hall, in Columbia, South Carolina, also known as Old United States Court House and Post Office, was built in 1870. It was listed on the National Register of Historic Places in 1973. It includes Renaissance architecture. It served historically as a courthouse and as a post office.It was designed by Alfred B. Mullett.

Sidney Park Colored Methodist Episcopal Church, also known as Sidney Park Christian Methodist Episcopal Church, is a historic Methodist Episcopal church located at Columbia, South Carolina. It was built in 1893, and is a brick Late Gothic Revival style church. It features the only set of octagonal towers in Columbia; each is topped by an octagonal steeple. The church also has lancet windows and pointed arches, wall buttresses, and a heavy timber truss system. The African-American congregation has a long history of involvement with civil rights activity and connection with the NAACP.It was added to the National Register of Historic Places in 1996.

The Columbia Museum of Art is an art museum in the American city of Columbia, South Carolina.

The Federal Land Bank Building, built in 1924, is a bank in Columbia, South Carolina. It was designed by architect A. Ten Eyck Brown. The Federal Land Bank Building was listed on the National Register of Historic Places in 2015.Construction began in 1923 and was completed in 1924. The building was added on to in 1935.

Canal Dime Savings Bank, also known as Eckerd's Drug Store, is a historic bank building located at Columbia, South Carolina. It was built between 1892 and 1895, and is a three-story, Romanesque Revival style brick building with a granite façade and red barrel tile roof. The building was purchased by Eckerd's Drug Store in 1936.It was added to the National Register of Historic Places in 1980.