John Hay High School

One University Circle is a mixed-used high rise in the University Circle district of Cleveland. It is located just down the block from the Cleveland Clinic as well as Case Western Reserve University on Euclid Avenue. Being constructed on the former location of the Children's Museum of Cleveland, the project is the first high-rise apartment building completed in the city in over 40 years. It houses 280 apartments, including penthouse apartments, a parking garage, concierge services, a fitness center, an outdoor swimming pool and a sky lounge offering bird's-eye views of the city.

Euclid Avenue is a major street in Cleveland, Ohio, United States. It runs northeasterly from Public Square in Downtown Cleveland, passing Playhouse Square and Cleveland State University, to University Circle, the Cleveland Clinic, Severance Hall, Case Western Reserve University's Maltz Performing Arts Center (formerly the Temple Tifereth Israel), Case Western Reserve University and University Hospitals Case Medical Center. The street runs through the suburbs of East Cleveland, Euclid, and Wickliffe, to Willoughby as a part of U.S. Route 20 and U.S. Route 6. The HealthLine bus rapid transit line runs in designated bus lanes in the median of Euclid Avenue from Public Square to Louis Stokes Station at Windermere in East Cleveland. It received nationwide attention from the 1860s to the 1920s for its beauty and wealth, including a string of mansions that came to be known as Millionaires' Row. There are several theaters, banks, and churches along Euclid, as well as Cleveland's oldest extant building, the Dunham Tavern. It can be reached through the Healthline.

The Elysium Arena was an indoor arena at the corner of E. 107th St. and Euclid in Cleveland, Ohio. It hosted the American Hockey League's Cleveland Falcons from 1936 to 1937. The arena held 3,500 people and opened in 1907. It was superseded in 1938 by the Cleveland Arena, and in 1951 was demolished by the city of Cleveland. Cleveland Hockey Club, champions of the 1920–21 United States Amateur Hockey Association, played at the Elysium Arena.

Artisan is a high rise apartment tower located in the University Circle district of Cleveland. The 24-story building stands 267-foot (81 m) tall, making it the tallest in the city outside of downtown. It was completed in 2023.

Michelson-Morley Memorial Fountain, also known as the Michelson-Morley Monument and commonly called the "lipstick fountain," is located on the campus of Case Western Reserve University in the University Circle neighborhood of Cleveland, Ohio. It was designed by William Behnke and built in 1973 in commemoration of the world-famous Michelson–Morley experiment.

The Case School of Engineering is the engineering school of Case Western Reserve University, a private research university in Cleveland, Ohio. It traces its roots to the 1880 founding of the Case School of Applied Science. The school was endowed by Leonard Case, Jr. in 1877 and became the Case Institute of Technology in 1947 until merging with Western Reserve University in 1967. It was officially named the Case School of Engineering in 1992.

Case Comprehensive Cancer Center (CCCC) is an NCI-designated Cancer Center in Cleveland, Ohio affiliated with Case Western Reserve University. It was founded in 1987.CCCC employs over 370 faculty members. It is a collaborative organization with the Cleveland Clinic Taussig Cancer Institute and University Hospitals Seidman Cancer Center.Case is organized into six research programs receiving NIH funding. In total, the center has received over $130 million in research funding.

Case Western Reserve University (CWRU) is a private research university in Cleveland, Ohio. Case Western Reserve was established after Western Reserve University—which was founded in 1826 and named for its location in the Connecticut Western Reserve—and Case Institute of Technology—which was founded in 1880 through the endowment of Leonard Case Jr.—formally federated in 1967. Case Western Reserve University comprises eight schools that offer more than 100 undergraduate programs and about 160 graduate and professional options across fields in STEM, medicine, arts, and the humanities. Notably, the Departments of Biomedical Engineering and Biochemistry, administered by the Case Western Reserve University School of Medicine, were respectively ranked 7th and 14th nationally for research activities and expenditures.In 2023, the university enrolled 12,266 students (6,186 undergraduate plus 6,080 graduate and professional) from all 50 states and 102 countries and employed more than 1,110 full-time faculty members. The university's athletic teams, Case Western Reserve Spartans, play in NCAA Division III as a founding member of the University Athletic Association. The Spartans compete in 10 men's and 9 women's varsity sports. Case Western Reserve University is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". According to the National Science Foundation, in 2019 the university had research and development (R&D) expenditures of $439 million, ranking it 20th among private institutions and 58th in the nation.Seventeen Nobel laureates are numbered among Case Western Reserve faculty or alumni, or one of its predecessors. The Michelson–Morley experiment disproving the existence of the "luminiferous aether" was conducted at Case Western in 1887, and Albert A. Michelson became the first American to win the Nobel Prize in science.

Adelbert Hall is an administration building at Case Western Reserve University in Cleveland, Ohio and a registered historic building, listed in the National Register on 1973-10-30.

University Hospitals Cleveland Medical Center (UH Cleveland Medical Center) is a large not-for-profit academic medical complex in Cleveland, Ohio, United States. University Hospitals Cleveland Medical Center is an affiliate hospital of Case Western Reserve University.UH Cleveland Medical Center is the main campus of the University Hospitals Health System. With 150 locations throughout the Cleveland metropolitan area, the University Hospitals Health System encompasses hospitals, outpatient centers, and primary care physicians. UH Cleveland Medical Center is home to world-class clinical and research centers, including cancer care, pediatrics, women's health, orthopedics, spine, radiology, radiation oncology, neurosurgery, neuroscience, psychiatry, cardiology, cardiovascular surgery, organ transplantation, and human genetics.

Severance Hall, also known as Severance Music Center, is a concert hall in the University Circle neighborhood of Cleveland, Ohio, home to the Cleveland Orchestra. Opened in 1931 to give the orchestra a permanent home, the building is named for patrons John L. Severance and his wife, Elisabeth Huntingdon DeWitt Severance. It is listed on the National Register of Historic Places as part of Cleveland’s Wade Park District.In addition to serving as the Cleveland Orchestra’s home and as a commencement site for Case Western Reserve University, Severance Hall is available to rent for concerts, weddings, corporate events, and receptions. On Severance Hall’s ground floor is Reinberger Chamber Hall, a separate 402-seat auditorium that is frequently used for more intimate performances and pre-concert lectures.

Allen Memorial Medical Library is located along Euclid Avenue on the campus of Case Western Reserve University in Cleveland, Ohio. Completed in 1926, the building was named in honor of Dudley P. Allen. Designed by the Cleveland firm of Walker and Weeks in a classical revival style, it was constructed with Indiana limestone on a pink Georgia marble base. It was listed in the National Register of Historic Places on 1982-11-30 and is a Cleveland Landmark. Along with serving as a library, the erection's 450 seat auditorium serves as classroom for students of Case Western Reserve University.In addition to housing a portion of the Cleveland Health Sciences Library (CHSL), it is also home of the Dittrick Museum of Medical History. The building is managed by the Cleveland Medical Library Association (CMLA) in a partnership with Case Western Reserve University.