St Mary's Road drill hall, Southampton

The Antelope Ground, Southampton was a sports ground that was the first home of both Hampshire County Cricket Club, who played there prior to 1884, and of Southampton Football Club, who played there from 1887 to 1896 as "Southampton St. Mary's F.C." The ground was situated on the east side of St Mary's Road at the corner of the present-day Brinton's Terrace and extended south to Clovelly Road and east to Exmoor Road. The ground took its name from the Antelope Hotel, which was situated on the opposite side of St Mary's Road.

The Royal South Hants Hospital, known locally as "The RSH", is a community hospital in Southampton. It is managed by NHS Property Services.

Solent University (formerly Southampton Solent University) is a public university based in Southampton, United Kingdom. It has approximately 10,500 students (2019/20). Its main campus is located on East Park Terrace near the city centre and the maritime hub of Southampton. Solent University students are represented by Solent Students' Union, which is based on the East Park Terrace campus.

Nicholstown-Newtown (usually called Nicholstown or Newtown) is a small area to the north-east of Southampton's city centre. To the north is Bevois Valley, to the east Northam and to the west and south is St Mary's. In the north of Newtown is the Mount Pleasant area, which spills over into the north of Northam. Black signs saying "Welcome to Nicholstown-Newtown" [1] demarcate the district on the roads running east from St. Mary's Rd – hence the district is bordered on the west by St. Mary's Road, the south by Six Dials road, and the east by the railway lines. The area is formed of residential streets with a typical parade of small shops and services; the exception is its central feature, Royal South Hampshire Hospital, established in 1843–1844.

The Franciscan Friary of Southampton was founded c. 1233. It occupied a south-eastern area of the city, within the walls and adjacent to God's House Tower. The friary was notable for its water supply system, which supplied water for use by the friars themselves and by the other inhabitants of Southampton. The friary was dissolved in 1538 and the last remains were swept away in the 1940s. The site is now occupied by Friary House. Elsewhere, remnants of the extensive water supply system still survive today.

The former offices of Ordnance Survey are situated in London Road, Southampton, close to the junction with The Avenue, and are now part of the city's court complex and are occupied by Government agencies. The buildings are Grade II listed.

The Southampton Courts of Justice is a Crown Court venue, which deals with criminal cases, as well as a County Court venue, which deals with civil cases, in London Road, Southampton, England.

The Southampton Central Parks are a set of five parks, which collectively make a central public park, in the heart of the city of Southampton. Created between 1854 and 1866, they have gained Grade II* listed status, as well as being part of the National Register of Historic Parks and Gardens. The parks are legally Common Land.

The Titanic Engineers' Memorial is a memorial in East (Andrews) Park, Southampton, United Kingdom, to the engineers who died in the Titanic disaster on 15 April 1912. The bronze and granite memorial was originally unveiled by Sir Archibald Denny, president of the Institute of Marine Engineers on 22 April 1914. The event was attended by an estimated 100,000 Southampton residents.

St Edmund's Church is a Roman Catholic parish church in Southampton, Hampshire. It is situated on the corner of The Avenue and Rockstone Place. It was built in 1889 and is a Grade II listed building.

Surge Radio is an English student radio station based at the University of Southampton. Founded in 1976 as Radio Heffalump, the station was renamed Radio Glen the following year and originally broadcast from the university's Glen Eyre Halls complex.

The Simon Flavell Leukaemia Research Laboratory is based at Southampton General Hospital and named after ten-year-old Simon Flavell who died in 1990 from an aggressive form of T-cell acute lymphoblastic leukemia (ALL). The laboratory specialises in researching and developing antibody type treatments for adults and children with currently incurable types of leukaemia. The laboratory was opened officially on 21 February 1993 by Gary Lineker and his former wife Michelle and in 2008 underwent a complete refurbishment. Originally part of the University of Southampton Medical School, The Simon Flavell Laboratory became independent in 2005 though still affiliated to the School of Medicine but now funded by the children’s leukaemia research charity Leukaemia Busters and other charitable sources. The Simon Flavell laboratory focuses on translational research designed to bring benefits to patients directly. In the early years the laboratory was involved in the development and manufacture of two different immunotoxins for treating patients with lymphoma, acute lymphoblastic leukaemia (ALL) and multiple myeloma in phase I clinical trials. This continues and now the laboratory is involved in developing the next generation of genetically engineered immunotoxins that should prove safer to use and cheaper to manufacture. A main theme of the laboratory’s current research work is to devise ways of improving the therapeutic window for immunotoxins to make them safer and more effective to use clinically. The laboratory is currently headed by Simon’s parents David Flavell and Sopsamorn (Bee) Flavell . The purpose of this Laboratory is to ensure that patients do not have to experience as much chemotherapy. The reason why this laboratory even opened was to support Simon Flavell and other people who have high potential for Leukemia, to make sure they would not have to experience as much pain.