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St Mary's is an inner city area of Southampton in England. It consists of two areas separated by Six Dials junction. The northern section of the district is bounded by St Mary's Road and some streets to the west and the area to the east is Nicholstown-Newtown. The northern section is home to the fire station.The majority of St Mary's is in the southern portion, to the east of St Mary Street. This is where St Mary's church is located, from which the suburb's name originates. The southern section is also home to the Golden Grove area. It is bordered on the east by the rail lines (the other side of these lines is the district of Chapel). It gives its name to St Mary's Stadium, where Southampton Football Club play, although the stadium itself is in the neighbouring suburb of Northam.

Nation Radio South Coast is a classic hits radio station broadcasting on 106 MHz & 106.6 MHz FM, on DAB on the South Hampshire multiplex across the South Coast of England and on DAB+ across a limited area on the Portsmouth small scale trial multiplex. The station is owned by Nation Broadcasting which was under a licensing agreement with operator Bauer Radio. In September 2022, the agreement ended and the station has become part of the Nation Radio network.As of December 2022, the station broadcasts to a weekly audience of 136,000, according to RAJAR.

The Joiners is a small music venue in a former pub (The Joiners Arms) on St Mary Street, St Mary's, Southampton, England. It has played host to many up-and-coming bands. The pub started having live acts in the back room in 1968. The maximum capacity is 200 people.In 2013, the venue was named Britain's best small music venue in a competition run by NME.In December 2006, writer Oliver Gray published a book entitled Access One Step: The Official History of the Joiners Arms, which documents the history of the venue and includes a foreword by Razorlight drummer Andy Burrows.

City College Southampton is a general further education college located in Southampton, Hampshire, England. The college has around 1000 full-time, 2500 part-time students and 450 apprentices each year. It offers a wide choice of full-time vocational courses including art & design, beauty, hairdressing, media, hospitality and catering, IT, performing arts, construction, engineering, business studies, care, travel & tourism, childcare, marine technology, boat building and technical theatre. The college teaches career-focused courses for young people and adults, both students and apprentices from 16 years old and further (no one is ever too old to learn). There are courses at all levels to prepare students for work or university and to improve key life skills. These include HNDs and HNCs, Access to Higher Education, BTEC Extended Diplomas and many other types of vocational course to give students the qualifications they need. The college trains apprentices. All of its apprentices are employed by a local business and train some of the time at college. Major local firms such as Griffon Hoverworks have high quality apprenticeship schemes. It runs other training courses for businesses and other organisations such as the local hospitals and City Council. Since September 2017 Solent University's Warsash Maritime School has been located at the campus.

St. Mary's Church, Southampton is a Church of England parish church, and the largest church in the port city of Southampton on the south coast of England. It is the mother church of this city with its forerunners spanning back to the first Saxon settlements of the 7th century, including a major collegiate church of the European Middle Ages dedicated to the same patron saint. Its name has been used nearby for major street names and in St Mary's Stadium, the city's largest sports stadium. Parts of the church date to the 1880s. In 1914 the sound of its church bells inspired the song, "The Bells of St. Mary's", originally recorded in 1919 by Frances Alda and later sung by Bing Crosby in a film of the same name.

Northam railway station served the suburb of Northam in Southampton, England.

The Franciscan Friary of Southampton was founded c. 1233. It occupied a south-eastern area of the city, within the walls and adjacent to God's House Tower. The friary was notable for its water supply system, which supplied water for use by the friars themselves and by the other inhabitants of Southampton. The friary was dissolved in 1538 and the last remains were swept away in the 1940s. The site is now occupied by Friary House. Elsewhere, remnants of the extensive water supply system still survive today.

Inspire Enterprise Academy (formerly Southampton Studio School) was a Studio school located in Southampton, designed for students aged 14–19 who intended to pursue a career in business and enterprise. It was founded in 2013 as part of the Studio Schools Trust. The school combined project-based learning and business experiences, with academic achievement, aimed at equipping students with a diverse range of skills. In September 2014 Inspire Enterprise Academy's sister, the Isle of Wight Studio School, opened on the Isle of Wight. On 6 July 2015 the school announced that it would close at the end of the academic year. The school formally closed in August 2015. Children in Year 10 were offered a transfer to the Isle of Wight Studio School.

St Mary's Stadium is an all-seater football stadium in Southampton, England, which has been the home stadium of Premier League club Southampton F.C. since 2001. The stadium has a capacity of 32,384 and is currently the largest football stadium in South East England. the Taylor Report on 29 January 1990 required all First and Second Division clubs to have all-seater stadiums by August 1994, Southampton's directors initially decided to upgrade The Dell into an all-seater stadium (which was completed in 1993) but speculation about relocation continued, especially as an all-seater Dell had a capacity of just over 15,000; despite this, Southampton continued to defy the odds and survive in the new FA Premier League after 1992. After a lengthy and ultimately unsuccessful attempt to build a new 25,000-seater stadium and leisure complex at Stoneham, on the outskirts of Southampton, the city council offered the club the chance to build a new ground on the disused gas work site in the heart of the city, about one and half miles from The Dell. The move was cited as the club returning home, because the club was formed by members of the nearby St. Mary's Church, as the football team of St. Mary's Church Young Men's Association before becoming Southampton St. Mary's F.C., and eventually Southampton F.C. Construction started in December 1999 and was completed at the end of July 2001, with work on the 32,689 seat stadium itself and improvements to local infrastructure cost a total of £32 million. The Saints have been in residence since August 2001 when they moved from The Dell, which for the final years of its life, held just over 15,000 spectators – less than half the size of the new stadium. The first match was played on 1 August 2001 against RCD Espanyol, with the Spanish side winning 4–3. The first competitive hat trick at the stadium was scored by Stafford Browne for Aldershot Town in a 3–1 victory over Havant & Waterlooville in the Hampshire Senior Cup final on 1 May 2002.In 2022, the stadium was used one of the venues to host the UEFA Women's Euro 2022. It was used to host Group A matches, which had the hosts England.

Nicholstown-Newtown (usually called Nicholstown or Newtown) is a small area to the north-east of Southampton's city centre. To the north is Bevois Valley, to the east Northam and to the west and south is St Mary's. In the north of Newtown is the Mount Pleasant area, which spills over into the north of Northam. Black signs saying "Welcome to Nicholstown-Newtown" [1] demarcate the district on the roads running east from St. Mary's Rd – hence the district is bordered on the west by St. Mary's Road, the south by Six Dials road, and the east by the railway lines. The area is formed of residential streets with a typical parade of small shops and services; the exception is its central feature, Royal South Hampshire Hospital, established in 1843–1844.

Solent University (formerly Southampton Solent University) is a public university based in Southampton, United Kingdom. It has approximately 10,500 students (2019/20). Its main campus is located on East Park Terrace near the city centre and the maritime hub of Southampton. Solent University students are represented by Solent Students' Union, which is based on the East Park Terrace campus.

The St Mary's Road drill hall is a former military installation in Southampton. It is a Grade II listed building.