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Simon Flavell Leukaemia Research Laboratory

1993 establishments in EnglandLeukemiaMedical research institutes in the United KingdomOrganisations based in Southampton

The Simon Flavell Leukaemia Research Laboratory is based at Southampton General Hospital and named after ten-year-old Simon Flavell who died in 1990 from an aggressive form of T-cell acute lymphoblastic leukemia (ALL). The laboratory specialises in researching and developing antibody type treatments for adults and children with currently incurable types of leukaemia. The laboratory was opened officially on 21 February 1993 by Gary Lineker and his former wife Michelle and in 2008 underwent a complete refurbishment. Originally part of the University of Southampton Medical School, The Simon Flavell Laboratory became independent in 2005 though still affiliated to the School of Medicine but now funded by the children’s leukaemia research charity Leukaemia Busters and other charitable sources. The Simon Flavell laboratory focuses on translational research designed to bring benefits to patients directly. In the early years the laboratory was involved in the development and manufacture of two different immunotoxins for treating patients with lymphoma, acute lymphoblastic leukaemia (ALL) and multiple myeloma in phase I clinical trials. This continues and now the laboratory is involved in developing the next generation of genetically engineered immunotoxins that should prove safer to use and cheaper to manufacture. A main theme of the laboratory’s current research work is to devise ways of improving the therapeutic window for immunotoxins to make them safer and more effective to use clinically. The laboratory is currently headed by Simon’s parents David Flavell and Sopsamorn (Bee) Flavell . The purpose of this Laboratory is to ensure that patients do not have to experience as much chemotherapy. The reason why this laboratory even opened was to support Simon Flavell and other people who have high potential for Leukemia, to make sure they would not have to experience as much pain.

Excerpt from the Wikipedia article Simon Flavell Leukaemia Research Laboratory (License: CC BY-SA 3.0, Authors).

Simon Flavell Leukaemia Research Laboratory
Carlton Place, Southampton The Polygon

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N 50.913236111111 ° E -1.4045166666667 °
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Carlton House

Carlton Place
SO15 2EA Southampton, The Polygon
England, United Kingdom
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Southampton Cenotaph
Southampton Cenotaph

Southampton Cenotaph is a First World War memorial designed by Sir Edwin Lutyens and located in Watts Park in the southern English city of Southampton. The memorial was the first of dozens by Lutyens to be built in permanent form and it influenced his later designs, including the Cenotaph in London. It is a tapering, multi-tiered pylon which culminates in a series of diminishing layers before terminating in a sarcophagus (or cenotaph, 'empty tomb') which features a recumbent figure of a soldier. In front is an altar-like Stone of Remembrance. The cenotaph contains multiple sculptural details including a prominent cross, the town's coat of arms, and two lions. The names of the dead are inscribed on three sides. Although similar in outline, later cenotaphs by Lutyens were much more austere and featured almost no sculpture. The design uses abstract, ecumenical features and lifts the recumbent soldier high above eye level, anonymising him. The memorial was unveiled at a public ceremony on 6 November 1920. Shortly afterwards, concerns emerged that the list of names on the cenotaph was incomplete. After a newspaper campaign, more than 200 further names were identified and these were eventually added to the cenotaph. The names of most Jewish casualties were omitted, the Jewish community being unhappy that the memorial featured a Christian cross. By the beginning of the 21st century, the engravings on the memorial had deteriorated noticeably. Rather than re-cut them and damage the stonework, they were supplemented by a series of glass panels that bear all the names from the cenotaph, as well as names from the Second World War and later conflicts. The panels were unveiled in 2011. The memorial is a Grade I listed building, having been upgraded in 2015 when Lutyens's war memorials were declared a national collection.