Beth Israel Deaconess Medical Center

The Medical Area Total Energy Plant, in Boston, Massachusetts, is a gas-fired co-generation power plant providing steam, chilled water, and electricity to the Longwood Medical Area. Proposed in 1974 and completed in 1986, the facility encountered fierce community opposition and cost $350 million‍—‌$310 million more than the originally projected $40 million.

The Massachusetts Mental Health Center is a historic psychiatric hospital complex at 75 Fenwood Road in the Longwood medical area of Boston, Massachusetts. The center was founded in 1912 as the Boston Psychopathic Hospital. Its original main building and power plant were built that year, with additions in later decades including a therapeutic wing (1954) and research building (1957). The entire property was surrounded by an iron picket fence. It was listed on the National Register of Historic Places in 1994, representing one of the nation's oldest psychiatric hospitals. In 2009 the center's historic campus at 74 Fenwood Road was acquired by Partners HealthCare and demolished the following year. The center continues to operate in modern facilities at 75 Fenwood Road.

The House of the Good Samaritan (sometimes called the Boston Good Samaritan Hospital) was a charitable, Boston hospital founded by Anne Smith Robbins in 1860. It accepted its first patients in 1861 and was established to care for destitute, chronically ill women and children. The hospital became affiliated in 1946 with Boston Children's Hospital. It was legally incorporated into Boston Children's Hospital in March 1967.

The Boston Psychopathic Hospital, established at 74 Fenwood Road in 1912, was one of the first mental health hospitals in Massachusetts, United States. The building was listed on the National Register of Historic Places in 1994. The name was changed to Massachusetts Mental Health Center in the late 1960s. The building at 74 Fenwood Road was closed in 2010 and demolished in 2011. The Massachusetts Mental Health Center continues to operate at 75 Fenwood Road.

Dana–Farber Cancer Institute is a comprehensive cancer treatment and research institution in Boston, Massachusetts. Dana–Farber is the founding member of Dana–Farber/Harvard Cancer Center, Harvard's Comprehensive Cancer Center designated by the National Cancer Institute, and one of the 15 clinical affiliates and research institutes of Harvard Medical School. As of 2023, Dana–Farber is ranked the #4 cancer hospital in the world. Two Nobel laureates in Physiology or Medicine are among its past and present faculty. Dana–Farber's research discoveries include the development of the highly successful Gleevec to treat chronic myeloid leukemia.

Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two founding members of Mass General Brigham, the largest healthcare provider in Massachusetts. Robert Higgins, MD, MSHA serves as the hospital's current president.Brigham and Women's Hospital conducts the second largest (behind MGH) hospital-based research program in the world, with an annual research budget of more than $630 million. Pioneering achievements at BWH have included the world's first successful heart valve operation and the world's first solid organ transplant. In the 2022 U.S. News & World Report hospital rankings, BWH was ranked fourteenth nationally.

Joslin Diabetes Center is the world's largest diabetes research center, diabetes clinic, and provider of diabetes education. It is located in the Longwood Medical and Academic Area in Boston, Massachusetts, United States. Among the Harvard Medical School affiliated institutions, Joslin is unique in its sole focus on diabetes. Joslin has the world's largest team of board-certified physicians treating diabetes and its complications, as well as the largest staff of Certified Diabetes Educators anywhere in the world. Joslin also supports the world's largest diabetes research team with more than 40 faculty investigators and more than 300 researchers.Roberta Herman, M.D., is currently President and CEO of Joslin Diabetes Center.

The Dutch House is a historic multi-unit residential building at 20 Netherlands Road in Brookline, Massachusetts. This four-story brick building was originally built as an exhibition hall at the 1893 World's Fair in Chicago, where it served as the Dutch Cocoa House. It is a close copy of the Franeker City Hall in Franeker, Netherlands. The door frame, embellished with stone animals, is a replica of the Enkhuizen Orphanage. The building's interior is highly ornate, with massive ceiling beams and Flemish wooden panels. The original dining room included classic blue and white Delftware tiles, some more than 300 years old. The exterior has a high mansard roof that extends over two floors, and has stepped gables. The windows include more than 12,000 individual lights of leaded green glass.The building was erected at the World's Fair by the Van Houten Cocoa Company, and was one of the few privately built fair buildings to win a medal. After the fair ended, the building was purchased by Brookline resident Charles Brooks Appleton, who had seen it there. The building was dismantled brick by brick and reconstructed at its present location, although some of its brickwork was covered by cement in imitation of stonework. It was placed on the National Register of Historic Places in 1986. Netherlands Road was named in honor of the house. Because it was built by the Netherlands and is a copy of a Dutch building, it is considered one of the finest examples of Dutch High Renaissance styling in the nation.

Mission Park station is a light rail stop on the MBTA Green Line E branch, located on Huntington Avenue in the Mission Hill neighborhood of Boston, Massachusetts. The station is located on a street running segment of the E branch; trains run in mixed traffic rather than a dedicated median. The station has no platforms; riders wait on the sidewalks (shared with bus stops for the route 39 and 66 buses) and cross the street to reach trains. Because of this, the station is not accessible. In 2021, the MBTA indicated plans to modify the Heath Street–Brigham Circle section of the E branch with accessible platforms to replace the existing non-accessible stopping locations.

Boston Children's Hospital formerly known as Children's Hospital Boston until 2013 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical School, and to Dana–Farber Cancer Institute. Dana–Farber and Children's jointly operate the Dana–Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital-based pediatric research program in the world. The hospital features 485 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an ACS verified level I pediatric trauma center, one of three in Boston. The hospital features a regional pediatric intensive-care unit and an American Academy of Pediatrics verified level IV neonatal intensive care unit. Boston Children's Hospital has been ranked as best pediatric medical center by U.S. News & World Report more times than any other hospital and is currently ranked as the best children's hospital in the United States. Its research enterprise is the world's largest and most highly funded pediatric hospital. In FY2022, Children's received more funding from the National Institutes of Health than any other children's hospital in the nation.

The Francis Street–Fenwood Road Historic District encompasses a small but cohesive early 20th-century residential area and streetcar suburb in the Longwood area of Boston, Massachusetts. Bounded by Huntington Avenue, Francis Street, Vining Avenue, Fenwood Road, and St. Albans Road, it includes a collection of two and three-family houses, as well as two apartment houses, a school, and one commercial building, all of which predate the large medical complexes that dominate the Longwood area. The district was listed on the National Register of Historic Places in 2016.

The Massachusetts School of Art is an historic academic building at 364 Brookline Avenue in the Longwood Medical Area of Boston, Massachusetts. The four-story Gothic/Art Deco building was designed by the architectural firm of Henry & Richmond, and was built in 1929-30 for the Massachusetts College of Art. The school occupied the building until 1983, when it moved to its present campus on Huntington Avenue. The building is now part of the Beth Israel Deaconess Medical Center. The building was listed on the National Register of Historic Places in 1989 and is currently under study for landmark status by the Boston Landmarks Commission.