Brigham and Women's Hospital

The House of the Good Samaritan (sometimes called the Boston Good Samaritan Hospital) was a charitable, Boston hospital founded by Anne Smith Robbins in 1860. It accepted its first patients in 1861 and was established to care for destitute, chronically ill women and children. The hospital became affiliated in 1946 with Boston Children's Hospital. It was legally incorporated into Boston Children's Hospital in March 1967.

Boston Children's Hospital formerly known as Children's Hospital Boston until 2013 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical School, and to Dana–Farber Cancer Institute. Dana–Farber and Children's jointly operate the Dana–Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital-based pediatric research program in the world. The hospital features 485 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an ACS verified level I pediatric trauma center, one of three in Boston. The hospital features a regional pediatric intensive-care unit and an American Academy of Pediatrics verified level IV neonatal intensive care unit. Boston Children's Hospital has been ranked as best pediatric medical center by U.S. News & World Report more times than any other hospital and is currently ranked as the best children's hospital in the United States. Its research enterprise is the world's largest and most highly funded pediatric hospital. In FY2022, Children's received more funding from the National Institutes of Health than any other children's hospital in the nation.

The Francis Street–Fenwood Road Historic District encompasses a small but cohesive early 20th-century residential area and streetcar suburb in the Longwood area of Boston, Massachusetts. Bounded by Huntington Avenue, Francis Street, Vining Avenue, Fenwood Road, and St. Albans Road, it includes a collection of two and three-family houses, as well as two apartment houses, a school, and one commercial building, all of which predate the large medical complexes that dominate the Longwood area. The district was listed on the National Register of Historic Places in 2016.

The Medical Area Total Energy Plant, in Boston, Massachusetts, is a gas-fired co-generation power plant providing steam, chilled water, and electricity to the Longwood Medical Area. Proposed in 1974 and completed in 1986, the facility encountered fierce community opposition and cost $350 million‍—‌$310 million more than the originally projected $40 million.

Paris-Saclay Medical School, also Faculté de médecine Paris-Saclay in French, is the graduate medical school of Paris-Saclay University and is located in the Bicêtre Medical Area of Le Kremlin-Bicêtre, Val-de-Marne, France and founded in 1968. It is the medical school of the first university in France according to its dean.

The Boston Psychopathic Hospital, established at 74 Fenwood Road in 1912, was one of the first mental health hospitals in Massachusetts, United States. The building was listed on the National Register of Historic Places in 1994. The name was changed to Massachusetts Mental Health Center in the late 1960s. The building at 74 Fenwood Road was closed in 2010 and demolished in 2011. The Massachusetts Mental Health Center continues to operate at 75 Fenwood Road.

Dana–Farber Cancer Institute is a comprehensive cancer treatment and research institution in Boston, Massachusetts. Dana–Farber is the founding member of Dana–Farber/Harvard Cancer Center, Harvard's Comprehensive Cancer Center designated by the National Cancer Institute, and one of the 15 clinical affiliates and research institutes of Harvard Medical School. As of 2023, Dana–Farber is ranked the #4 cancer hospital in the world. Two Nobel laureates in Physiology or Medicine are among its past and present faculty. Dana–Farber's research discoveries include the development of the highly successful Gleevec to treat chronic myeloid leukemia.

The Longwood Medical and Academic Area (also known as Longwood Medical Area, LMA, or simply Longwood) is a medical campus in Boston, Massachusetts. Flanking Longwood Avenue, LMA is adjacent to the Fenway–Kenmore, Audubon Circle, and Mission Hill neighborhoods, as well as the town of Brookline.It is most strongly associated with Harvard Medical School, the Harvard T.H. Chan School of Public Health, the Harvard School of Dental Medicine, and other medical facilities such as Harvard's teaching hospitals, but prominent non-Harvard institutions are located there as well. Long known as a global center of research, institutions in the Longwood Medical Area secured over $1.2 billion in NIH funds alone, in FY 2018 which exceeds funding received by 44 states.

Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School. It was formed out of the 1996 merger of Beth Israel Hospital (founded in 1916) and New England Deaconess Hospital (founded in 1896). Among independent teaching hospitals, Beth Israel Deaconess Medical Center consistently ranks in the top three recipients of biomedical research funding from the National Institutes of Health. Research funding totals nearly $200 million annually. BIDMC researchers run more than 850 active sponsored projects and 200 clinical trials. The Harvard-Thorndike General Clinical Research Center, the oldest clinical research laboratory in the United States, has been located on this site since 1973.

Fenwood Road station is a light rail stop on the MBTA Green Line E branch, located on Huntington Avenue at Fenwood Road in the Mission Hill neighborhood of Boston, Massachusetts. Fenwood Road is the third-least-used stop on the Green Line (after Back of the Hill and South Street), with 221 daily boardings by a 2011 count.The station is located on a street running segment of the E branch; trains run in mixed traffic rather than a dedicated median. The station has no platforms; riders wait on the sidewalks (shared with bus stops for the route 39 and 66 buses) and cross the street to reach trains. Because of this, the station is not accessible. In 2021, the MBTA indicated plans to modify the Heath Street–Brigham Circle section of the E branch with accessible platforms to replace the existing non-accessible stopping locations.

The Massachusetts School of Art is an historic academic building at 364 Brookline Avenue in the Longwood Medical Area of Boston, Massachusetts. The four-story Gothic/Art Deco building was designed by the architectural firm of Henry & Richmond, and was built in 1929-30 for the Massachusetts College of Art. The school occupied the building until 1983, when it moved to its present campus on Huntington Avenue. The building is now part of the Beth Israel Deaconess Medical Center. The building was listed on the National Register of Historic Places in 1989 and is currently under study for landmark status by the Boston Landmarks Commission.

Brigham Circle is located at the intersection of Tremont Street and Huntington Avenue in the Mission Hill neighborhood of Boston, Massachusetts. The commercial center of Mission Hill, it forms the southern tip of the Longwood Medical Area.The area is named for the Peter Bent Brigham Hospital (now a wing of the larger Brigham and Women's Hospital), which stands at one side of the circle and is approached through Stoneman Plaza. The intersection was never a true traffic circle like other circles in Boston. Huntington Avenue has had through lanes since at least the early 20th century; a small rotary was present at the junction of Francis Street on the northwest side. Near MBTA stops is a street-level park with metal benches that sites farmers' markets, and entrances to Kevin W. Fitzgerald Park (formerly Puddingstone Park) and other parks are nearby.