American Grain Complex

SS Columbia is the last remaining excursion steamship from the turn of the 20th century in existence, the second to last being her running mate and sister ship SS Ste. Claire which burned in 2018. Both were designed by Frank E. Kirby and Louis O. Keil. Columbia was listed on the National Register of Historic Places in 1979, and was designated a National Historic Landmark in 1992. As of 2019, the vessel is docked at Silo City in Buffalo, New York while work is being done to rehabilitate it.

Queen City Landing was an approved residential tower proposal by developer Gerald Buchheit on the Outer Harbor of Buffalo, New York. Preparation work included the demolition of a 6-story warehouse formerly operated by Freezer Queen Foods and the project was planned to have approximately 200 apartment units. Upon completion, it would have been the 6th tallest building in Buffalo and the 13th tallest in Upstate New York, with a height of 324 feet and 23 floors. The tower was targeted in a lawsuit by local environmentalists out of concern that it posed a danger to bird migration, given its immediate proximity to the Tifft Nature Preserve, and also that the city board did not conduct a full environmental study on the site. However, on multiple occasions, a state Supreme Court judge upheld the city board's decision to build the tower and also ruled that the city acted properly in its environmental study. Bucheit completed the environmental cleanup of the site in late 2018.On November 18, 2019, Bucheit announced a slight change in the tower's design. The building would be reduced to 20 stories and would be moved farther away from the water, in addition to occupying 30 percent less land. The new finish date was tentatively projected to 2021. In addition, Bucheit also added plans for a surrounding neighborhood around the main tower complete with two 6-story apartment buildings, a cluster of 3-story townhouses, and more public space. However, in light of the COVID-19 pandemic, continued resistance from the plaintiffs, and an inability to secure public funding from the city, the project was "suspended indefinitely" in March 2020 and presumably cancelled for good the following year when the developer listed the property for sale.

The Great Northern Elevator is a grain storage facility at 250 Ganson Street in Buffalo, New York. The elevator is located along Buffalo's "elevator alley" and at the time of its completion in 1897, the elevator was the world's largest. The mill was also one of the first to run on electricity.

E. & B. Holmes Machinery Company Building, also known as The Cooperage, is a historic factory building located at Buffalo in Erie County, New York. It is a roughly rectangular brick building composed of three primary sections of four-, three-, and two-stories, which encircle a central courtyard. The three sections are the Mill Building (ca. 1870), Forge Building (ca. 1910-1912), and Pattern Building (1913). The E. & B. Holmes Machinery Company revolutionized the barrel making industry by patenting the design and manufacturing of machinery used for mass-producing barrels. The company operated from 1840 until 2002.Plans announced in January 2010 are for the complex to be converted to "live and work" apartments and commercial space by Newark Niagara LLC in partnership with Clinton Brown Company Architecture. More information about the project can be found at River Lofts Buffalo. It was listed on the National Register of Historic Places in 2009.

Concrete-Central Elevator is a historic grain elevator located on the Buffalo River at 175 Buffalo River (750 Ohio St.) Buffalo in Erie County, New York.

Buffalo RiverWorks is a multipurpose indoor venue and restaurant located on the shore of the Buffalo River in Buffalo, New York.

DL&W station is a Buffalo Metro Rail light rail indoor station currently under construction. It is planned for the first floor on the Buffalo River side of the former Delaware, Lackawanna and Western Railroad terminal, which currently serves as the NFTA Rail Maintenance Yard. This station will eliminate the Special Events station and provide commuters access to parking and Metro Rail service to the city, and a direct pedestrian walkway to Canalside areas.

The Metro Rail Maintenance Yard or "South Park Terminal" houses Buffalo Metro Rail's cars in a train shed at the former Delaware, Lackawanna and Western Railroad terminal in the Cobblestone District of Buffalo, New York. The property is located at the southernmost fringe of the Central Business District. The station was built in 1917, and was designed to handle both steam trains and steamships. The storage and maintenance facility was converted to its present condition in 1982, following the demolition of the former main terminal concourse building "headhouse" of the DL&W Terminal in 1979. The lower level of the sheds are used to store the rail cars when they are not in use. The upper level is mostly empty space, consisting of the concrete troughs where tracks once stood and their platforms. However, some of it is used for offices, a train operators' lounge and storage. Numerous proposals for adaptive reuse of the unused portion of the upper level of the terminal sheds have been floated publicly by various parties, including: a casino, a farmers market and loft apartments, while the lower floor is currently undergoing reconstruction to accommodate a new Metro Rail station. In 1982, an addition was built on the east end of the terminal building, which has a modern rail maintenance shop for servicing the rail fleet. This addition also contains some administrative offices.

Buffalo Harbor State Park is a 190-acre (0.77 km2) state park and marina on the shore of Lake Erie in the city of Buffalo in Erie County, New York. The park encompasses Gallagher Beach, the former NFTA Small Boat Harbor, and the waterfront land in between.

The Tifft Nature Preserve is a 264-acre nature preserve in Buffalo, New York, and one of the largest municipal nature preserves in New York.

KeyBank Center is a multipurpose indoor arena located in Buffalo, New York. Originally known as Marine Midland Arena, the venue has since been named HSBC Arena and First Niagara Center. Home to the Buffalo Sabres of the National Hockey League since 1996, is the largest indoor arena in Western New York, seating 19,070. It replaced the Sabres' former home, Buffalo Memorial Auditorium, where the team played from 1970 to 1996. The venue is also home to the Buffalo Bandits of the National Lacrosse League. KeyBank Center was previously home to the Canisius Golden Griffins (NCAA), Buffalo Blizzard (NPSL), Buffalo Wings (RHI) and Buffalo Destroyers (AFL). In addition to concerts and professional wrestling, the venue has hosted major events including the NCAA Division I Men's Basketball Tournament, 1999 Stanley Cup Finals, 2003 Frozen Four and UFC 210.

The Helene Fuld Health Trust is the largest charitable trust in the United States devoted exclusively to supporting student nurses and nursing education. The trust — which began as a foundation in 1935, but transferred its assets to the trust in 1969 — has provided grants, scholarships, and financial aid for the education, health, and welfare of student nurses.