Seneca One Tower

The Marin, previously the Main Seneca Building, and originally known as the Marine Midland Trust Company Building or the "Marine Trust Building," is a 17-story Renaissance Revival style highrise in downtown Buffalo, New York. The building was previously the headquarters for Marine Midland Bank before the bank constructed One Marine Midland Center at 1 Seneca Tower, the tallest building in Buffalo.

Seneca (officially Merchants Insurance @ Seneca since June 27, 2019 for sponsorship purposes) is a Buffalo Metro Rail station located in the 200 block of Main Street between Seneca and Swan Streets in the Free Fare Zone, which allows passengers free travel between Erie Canal Harbor and Fountain Plaza station. Passengers continuing northbound past Fountain Plaza are required to provide proof-of-payment. On June 27, 2019, The Buffalo News announced that Merchants Insurance, which has been located at 260 Main Street since the 1960s, bought the naming rights for $161,000 for initially five years, with the option to renew for another five years.

The Lehigh Valley Terminal was a railroad station in downtown Buffalo, New York. The Lehigh Valley Railroad opened it in 1916, replacing an older station one block east at Scott and Washington streets. Lehigh Valley trains served at the station included the Black Diamond, Maple Leaf and Star. The station handled the Lehigh Valley's passenger traffic in Buffalo until 1955, when it was demolished to make room for the Niagara Thruway (Interstate 190). The Lehigh Valley moved its operations to a smaller station outside the downtown area at Dingens and South Ogden Streets, which served until the end of all Lehigh Valley passenger service in 1961. The terminal also hosted the Erie Railroad's passenger trains from 1935 until 1951, when that railroad ceased serving Buffalo.

Erie Canal Harbor (formerly Auditorium until September 1, 2003) is a Buffalo Metro Rail station located in the 100 block of Main Street (just north of Hanover and Scott Streets) next to the South Aud Block of Canalside in the Free Fare Zone, which allows passengers free travel between this station and Fountain Plaza station. Passengers continuing past Fountain Plaza are required to provide proof-of-payment. Unless there are events occurring at KeyBank Center, in which case Special Events station will be utilized, this is the southern terminus of Metro Rail. Since Erie Canal Harbor station serves as a terminal, immediately north is a double crossover. Erie Canal Harbor station is located close to Amtrak's Buffalo–Exchange Street station and the two stations are connected by a lit pathway beneath Interstate 190 with decorative cement and signage.

Buffalo–Exchange Street station is an Amtrak station in Buffalo, New York. The station serves six Amtrak trains daily: two daily Empire Service round trips between Niagara Falls and New York City and one Maple Leaf round trip between Toronto and New York City. There is also daily Amtrak Thruway bus service (operated by Coach USA) at the station, operating between the Buffalo Metropolitan Transportation Center and Jamestown station in Jamestown, New York, via Dunkirk and Fredonia, and serving the communities along the southeast shore of Lake Erie.Local transportation is provided by the Niagara Frontier Transportation Authority (NFTA), which operates buses and the Buffalo Metro Rail. Buffalo–Exchange Street is located close to Metro Rail's Erie Canal Harbor station and the two stations are connected by a lit pathway beneath Interstate 190 with decorative cement and signage. The station is close to the KeyBank Center and Sahlen Field. The station has one high-level side platform on the north side of two tracks. It is one of two stations in the Buffalo area, the other being Buffalo–Depew station which serves the Lake Shore Limited. The current station is the fifth train station to be built at the current site, it was opened in 2020.

Sahlen Field is a baseball park in Buffalo, New York, United States. Originally known as Pilot Field, the venue has since been named Downtown Ballpark, North AmeriCare Park, Dunn Tire Park, and Coca-Cola Field. Home to the Buffalo Bisons of the International League, it opened on April 14, 1988 and can seat up to 16,600 people, making it the highest-capacity Triple-A ballpark in the United States. It replaced the Bisons' former home, War Memorial Stadium, where the team played from 1979 to 1987. The stadium was the first retro-classic ballpark built in the world, and was designed with plans for Major League Baseball (MLB) expansion. Buffalo had not had an MLB team since the Buffalo Blues played for the Federal League in 1915. However, Bisons owner Robert E. Rich Jr. was unsuccessful in his efforts to bring an MLB franchise to the stadium between 1988 and 1995. The stadium was a temporary home to the Toronto Blue Jays of MLB in 2020 and 2021 when they were displaced by the COVID-19 pandemic. Sahlen Field was previously home to the Buffalo Nighthawks of the Ladies Professional Baseball League in 1998, the Buffalo Bulls of the National Collegiate Athletic Association in 2000, and the Empire State Yankees of the International League in 2012. In addition to concerts and professional wrestling, the stadium has hosted major events including the National Old-Timers Baseball Classic (1988–1990), Triple-A All-Star Game (1988, 2012), StarGaze (1992–1993), World University Games (1993) and National Buffalo Wing Festival (2002–2019).

Buffalo Memorial Auditorium, colloquially known as The Aud, was a multipurpose indoor arena in downtown Buffalo, New York. Opened on October 14, 1940, it was home to the Canisius Golden Griffins (NCAA), the Buffalo Bisons (AHL), the Buffalo Bisons (NBL), the Buffalo Braves (NBA), the Buffalo Sabres (NHL), the Toronto-Buffalo Royals (WTT), the Buffalo Stallions (MSL), the Buffalo Bandits (MILL), the Buffalo Blizzard (NPSL) and the Buffalo Stampede (RHI). It also hosted events such as college basketball, concerts, professional wrestling and boxing. The venue was closed in 1996 after the construction of Marine Midland Arena, and remained vacant until being demolished in 2009.

The Fidelity Trust Building, also known as Swan Tower, is a 160,000-square-foot (15,000 m2) commercial Renaissance Revival office building located at 284 Main Street in the Joseph Ellicott Historical District (also called the Downtown Historic District) in downtown Buffalo, New York.

The Ellicott Square Building is a historic office complex, completed in 1896, located in Buffalo, New York.

Explore & More - The Ralph C. Wilson, Jr. Children's Museum is a museum in Buffalo, New York. The museum is for and about Buffalo - with seven play zones and three educational studios that are used to tell the unique story of Western New York. Designed for children from birth - 12 years of age, these hands-on play zones encourage children to explore their interests through the power of play. It was founded in 1994 in East Aurora, New York. In 2019, the museum moved from East Aurora to the Canalside district of Buffalo. Many of the former exhibits from the East Aurora location were donated to the Children's Activity Corner of Jamestown. On February 14, 2018, the Ralph C. Wilson Jr. Foundation awarded a $6 million grant to the museum and the then-under construction Canalside museum was re-named in honor of Wilson.The museum is located at 130 Main St. Buffalo, NY 14202.

LECOM Harborcenter is an American mixed-use development in Buffalo, New York developed by Pegula Sports and Entertainment. The building occupies a full 1.7 acre city block formerly known as the Webster Block, directly across from and connected to the KeyBank Center and Canalside. The building is also near the southern terminus of the Erie Canal Harbor (Metro Rail) station. The development features retail and restaurant space, a 205-room Buffalo Marriott Harborcenter Hotel, as well as two hockey rinks that are the home of the Buffalo Jr. Sabres of the Ontario Junior Hockey League, the Canisius Golden Griffins of the NCAA, and the Erie Kats of the National Junior College Athletic Association. The rinks are also the Buffalo Sabres practice facility.

The Helene Fuld Health Trust is the largest charitable trust in the United States devoted exclusively to supporting student nurses and nursing education. The trust — which began as a foundation in 1935, but transferred its assets to the trust in 1969 — has provided grants, scholarships, and financial aid for the education, health, and welfare of student nurses.