28th Police Precinct Station

The 103rd Street station is a local station on the IRT Lexington Avenue Line of the New York City Subway. Located at the intersection of Lexington Avenue and 103rd Street in East Harlem, it is served by the 6 train at all times, the <6> train during weekdays in the peak direction, and the 4 train during late nights. This station was constructed as part of the Dual Contracts by the Interborough Rapid Transit Company and opened in 1918. It was renovated in 1990 and in 2015-2016.

The Taller Boricua, in Manhattan, New York is a multidisciplinary cultural space founded in 1969 by Puerto Rican artists to promote the arts and culture of the Puerto Rican community in El Barrio/East Harlem, as well as to offer a platform to underrepresented and marginalized artists.It is located at the Julia de Burgos Latino Cultural Center.Its founders were a group of activists, intellectuals and young artists such as Carlos Osorio, Rafael Tufino, Fernando Salicrup, Marcos Dimas and Nitza Tufiño. This artist-run non profit gallery offer art exhibitions, artist talks, workshops and art classes that take place throughout the year and aim to curb the economic, cultural and social disparities in the area.

The Lexington Avenue explosion was the July 4, 1914, explosion of a terrorist bomb in an apartment at 1626 Lexington Avenue in New York City. Members of the Lettish section of the Anarchist Black Cross (ABC) were constructing a bomb in a seven-story tenement when the group's large supply of dynamite exploded prematurely. The blast destroyed most of the top three floors of the building, killing three conspirators and another renter who was not part of the bomb plot, as well as injuring dozens more.

Union Settlement is one of the oldest settlement houses in New York City, providing community-based services and programs that support the immigrant and low-income residents of East Harlem since 1895. It is East Harlem’s largest social service agency and serves 10,000 people annually through programs including early childhood education, youth services, senior services, adult education, mental health, small business development and community outreach.

St. Cecilia Church is a Roman Catholic parish church in the Roman Catholic Archdiocese of New York and a historic landmark located at 120 East 106th Street between Park Avenue and Lexington Avenue, Manhattan, New York City, New York. The parish was established in 1873. It was staffed by the Redemptorist Fathers from 1939 to 2007. The church was designated a New York City landmark in 1976. The church and convent were listed on the U.S. National Register of Historic Places in 1984.

Duffy's Hill is a hill located on Lexington Avenue between 102nd and 103rd Streets in the East Harlem neighborhood of Manhattan, New York City. It was named for Michael James Duffy, a Tammany Hall Alderman who spent $250,000 to build 26 rowhouses on the south side of 101st Street between Lexington and Park Avenues in 1894. He continued building between Third Avenue and Lexington Avenue up to 104th Street, a section of the city sometimes known at the time as "Duffyville".The hill marked the site of cable car accidents by 1897, as the cars had to quickly accelerate and decelerate at this point. The New York Railways Corporation had a 24-hour guard stationed at the base of the hill at 103rd Street by 1937 to watch over streetcar incidents related to the hill. At one time, Lexington Avenue buses would detour onto Park Avenue to avoid the hill.The National Board of Fire Underwriters noted that Lexington Avenue's grade of 12.6% was the steepest of any "important localit[y]" in Manhattan. The entrances to the 103rd Street station of the New York City Subway, served by the 6 and <6>​ trains, are located at the bottom of the hill.

The Church of the Holy Agony was a Roman Catholic parish church in the Roman Catholic Archdiocese of New York, located at 1834 Third Avenue and 101st Street, in the East Harlem section of Manhattan, New York City. The parish was established in 1930 as a mission of Our Lady of the Miraculous Medal. The parish is staffed by the Vincentian Fathers. In November 2014, the Archdiocese announced that the Church of the Holy Agony was one of 31 neighborhood parishes which would be merged into other parishes. Holy Agony was to be merged into the Church of St. Cecilia at 125 East 105th Street.The church was deconsecrated on June 30, 2017.

Cristo Rey New York High School is a college preparatory, Catholic high school located in East Harlem, Manhattan, New York City, and a member of the Cristo Rey Network of schools. The school follows a unique Corporate Work Study Model, which allows students to spend one day per week interning with multinational corporations such as McKinsey, Pfizer, American Express, and JPMorgan Chase. Since its opening in 2004, Cristo Rey New York has produced 943 alumni.

The Gaylord White Houses is a New York City Housing Authority housing building with 20 stories and the southern rectangle stub in the same building is 8 stories. It is connected to a reconstructed 3-story Union Center Community Center at 237 East 104th Street from 1964 to the present. It is located in the corner of East 104th Street and 2nd Avenue in East Harlem, Manhattan.

The 105th Street station was a local station on the demolished IRT Second Avenue Line in Manhattan, New York City. It had three tracks and two side platforms. The next stop to the north was 111th Street. The next stop to the south was 99th Street. The station closed on June 11, 1940.

106th Street is a planned station along the IND Second Avenue Line of the New York City Subway. It would be located at the intersection of Second Avenue and 106th Street in East Harlem, Manhattan. Proposed since 1968, the station is expected to be built by 2027–2029 as part of Phase 2 of the Second Avenue Subway. When opened, it will initially be served by the Q train, with the T train providing service when Phase 3 of the line is built.

99th Street was a local station on the demolished IRT Third Avenue Line in Manhattan, New York City. The station was originally built by the Manhattan Railway Company on December 30, 1878, and later had two levels. The lower level serving local trains was built first, and had two tracks and two side platforms. The upper level, built as part of the Dual Contracts had one track that bypassed the station and served express trains. This station closed on May 12, 1955, with the ending of all service on the Third Avenue El south of 149th Street. South of the station were connecting tracks to the 98th Street Yard. The station was also located next to Substation 7 an old IRT substation designed not only in order to electrify the Third Avenue Line, but the Second and Ninth Avenue elevated lines as well. Later it even served as a power source for the IRT Lexington Avenue Line from 1918 until the 1970s. The substation is still owned by the MTA and has been listed on the National Register of Historic Places since February 9, 2006.