106th Street station (Second Avenue Subway)

The 105th Street station was a local station on the demolished IRT Second Avenue Line in Manhattan, New York City. It had three tracks and two side platforms. The next stop to the north was 111th Street. The next stop to the south was 99th Street. The station closed on June 11, 1940.

Union Settlement is one of the oldest settlement houses in New York City, providing community-based services and programs that support the immigrant and low-income residents of East Harlem since 1895. It is East Harlem’s largest social service agency and serves 10,000 people annually through programs including early childhood education, youth services, senior services, adult education, mental health, small business development and community outreach.

St. Lucy's Church is a former parish church of the Parish of St. Lucy, which operated under the authority of the Archdiocese of New York in the East Harlem section of the Borough of Manhattan in New York City. The parish address was 344 East 104th Street; the parochial school occupied 336 East 104th Street. The parish merged with St. Ann's Church in 2015, and Masses and other sacraments are no longer offered regularly at this church. The church was deconsecrated on June 30, 2017.

St. Ann's Church is a Roman Catholic parish church in the Roman Catholic Archdiocese of New York, located at 312 East 110th Street, in the East Harlem section of the Borough of Manhattan in New York City.

St. Ann, The Personal School is a Catholic pre-kindergarten and K–8 school in Upper Manhattan, located in East Harlem at 314 East 110th Street, New York City. It was founded in 1926. The principal is Mrs. Teresa Letizia.

The 111th Street station was a local station on the demolished IRT Second Avenue Line in Manhattan, New York City. It had three tracks and two side platforms. The next stop to the north was 117th Street. The next stop to the south was 105th Street. The station closed on June 11, 1940.

Metropolitan Park is a former baseball ground located in East Harlem, Manhattan, New York. The ground was the part-time home to the New York Metropolitans of the American Association in 1884. The wooden ballpark was built a few blocks east and south from their first home, the original Polo Grounds, on a piece of land bounded by 109th Street (north), the Harlem River (east), 107th Street (south), and First Avenue (west). It was built a block east and north of the site of the Red House hotel and grounds, which had hosted trotting, cricket and baseball from 1833 until its demise in about 1867. The park had been built on a former dumping ground, a fact which contributed to its quick demise. It also suffered from the various swamp-related unpleasantries, such as mosquitoes, which had led to the shutdown of the Red House grounds. The Mets played their first game at Metropolitan Park on May 13, 1884, amid a degree of publicity. However, the park proved unsatisfactory, and was soon labeled "The Dump" by players and other observers (especially sports reporters working for the Brooklyn Eagle). The Mets returned to the Polo Grounds for games starting on July 17, 1884, except when the New York Giants were playing at home. The final Mets game played at Metropolitan Park was on August 23, 1884. The Mets then returned to their original Polo Grounds venue, in time to win the American Association pennant. The park continued to be used for occasional amateur baseball and football for a year or two after the Mets abandoned it. The block is now occupied by a complex of residential, commercial and school buildings.

The Taller Boricua, in Manhattan, New York is a multidisciplinary cultural space founded in 1969 by Puerto Rican artists to promote the arts and culture of the Puerto Rican community in El Barrio/East Harlem, as well as to offer a platform to underrepresented and marginalized artists.It is located at the Julia de Burgos Latino Cultural Center.Its founders were a group of activists, intellectuals and young artists such as Carlos Osorio, Rafael Tufino, Fernando Salicrup, Marcos Dimas and Nitza Tufiño. This artist-run non profit gallery offer art exhibitions, artist talks, workshops and art classes that take place throughout the year and aim to curb the economic, cultural and social disparities in the area.

The 110th Street station is a local station on the IRT Lexington Avenue Line of the New York City Subway. Located in East Harlem at the intersection of 110th Street and Lexington Avenue, it is served by the 6 train at all times, the <6> train during weekdays in the peak direction, and the 4 train during late nights. This station was constructed as part of the Dual Contracts by the Interborough Rapid Transit Company and opened in 1918. It was renovated from 2002 to 2004.

The 1199 Plaza is a housing project in East Harlem. Located on First Avenue, on the western bank of the East River, the 1199 Plaza consists of four 31-story towers, joined by mid-rise units which extend toward the riverbank. 1199 Plaza opened in 1974, as a low-to-middle income housing project. The 1199 Plaza traces its origin to the 1199 union, which consisted mainly of female lower-income hospital workers. The 1199 union members wanted housing that was safe, affordable, and socially inclusive. Hodne/Stageberg Partners, Inc served as the architects of the project, while Ruberoid supplied building materials. In the 1990s, the 1199 Plaza began offering housing for non-HUD applicants. A new title, East River Landing, was adopted. The 1199 Plaza has thus become a hybrid project, housing both middle-income and higher-income applicants, in addition to poorer residents. The 1199 Plaza has been described as a "city within a city", owing to its sheer scale and unique design.

Our Lady Queen of Angels Catholic Elementary School, commonly referred to as Queen of Angels School, is a Catholic elementary school located in the East Harlem neighborhood of Manhattan, New York City. The school was founded by the parish friars in 1892 and was originally staffed by the Sisters of St. Agnes. Today it is run by lay teachers and is administered by the Partnership for Inner-City Education in conjunction with the Archdiocese of New York. On 25 September 2015, Pope Francis visited Queen of Angels School as part of his New York stop in his papal visit to Cuba and the United States.

St. Cecilia Church is a Roman Catholic parish church in the Roman Catholic Archdiocese of New York and a historic landmark located at 120 East 106th Street between Park Avenue and Lexington Avenue, Manhattan, New York City, New York. The parish was established in 1873. It was staffed by the Redemptorist Fathers from 1939 to 2007. The church was designated a New York City landmark in 1976. The church and convent were listed on the U.S. National Register of Historic Places in 1984.