Renaissance Ballroom & Casino

The Abyssinian Baptist Church is a Baptist megachurch located at 132 West 138th Street between Adam Clayton Powell Jr. Boulevard and Lenox Avenue in the Harlem neighborhood of Manhattan, New York City. It is affiliated with the National Baptist Convention, USA and American Baptist Churches USA. Its senior pastor is Johnnie D. Brooker, Jr.. The Abyssinian Baptist Church congregation traces its history to 1809, when seamen from the Ethiopian Empire (then known as Abyssinia) helped lead a protest against racially segregated church seating. Thomas Paul was an early minister. During the 20th century, prominent ministers of the church included Adam Clayton Powell Sr., Adam Clayton Powell Jr., and Samuel DeWitt Proctor. The church has served as an influential place for African-American spirituality, politics and community. The church worshiped in several places before building the present church structure Its present building was built in 1922–23 and was designed by Charles W. Bolton & Son in Gothic Revival and Tudor Revival styles – it has also been described as "Collegiate Gothic". It features stained glass windows and marble furnishings. The church and its associated community house were designated a New York City Landmark on July 13, 1993.

The Mother African Methodist Episcopal Zion Church, also known as "Mother Zion", located at 140–148 West 137th Street between Adam Clayton Powell Jr. Boulevard and Lenox Avenue in the Harlem neighborhood of Manhattan, New York City, is the oldest African-American church in New York City, and the "mother church" of the African Methodist Episcopal Zion conference.The church was designated a New York City Landmark on July 13, 1993.

The Will Marion Cook House is a historic townhouse at 221 West 138th Street, in the part of Harlem known as Strivers' Row in Manhattan, New York City. It was the home of Will Marion Cook (1869-1944), a leading African-American musician and composer of the period, from 1918 until his death in 1944. Cook was a major influence on later musicians including Sidney Bechet, Duke Ellington, and Josephine Baker. It was declared a National Historic Landmark in 1976.

The St. Nicholas Historic District, known colloquially as "Striver's Row", is a historic district located on both sides of West 138th and West 139th Streets between Adam Clayton Powell Jr. Boulevard (Seventh Avenue) and Frederick Douglass Boulevard (Eighth Avenue), in the Harlem neighborhood of Upper Manhattan, New York City. It is both a national and a New York City historic district, and consists of row houses and associated buildings designed by three architectural firms and built in 1891–93 by developer David H. King Jr. These are collectively recognized as gems of New York City architecture, and "an outstanding example of late 19th-century urban design":There are three sets of buildings: the red brick and brownstone buildings on the south (even-numbered) side of West 138th Street and at 2350–2354 Adam Clayton Powell Jr. Boulevard were designed by James Brown Lord in the Georgian Revival style; the yellow brick and white limestone with terra cotta trim buildings on the north (odd-numbered) side of 138th and on the south (even-numbered) side of 139th Street and at 2360–2378 Adam Clayton Powell Jr. Boulevard were designed in the Colonial Revival style by Bruce Price and Clarence S. Luce; the dark brick, brownstone and terra cotta buildings on the north (odd-numbered) side of 139th Street and at 2380 Adam Clayton Powell Jr. Boulevard were designed in the Italian Renaissance Revival style by Stanford White of the firm McKim, Mead & White.The district was designated by the New York City Landmarks Preservation Commission in 1967, and was listed on the National Register of Historic Places in 1975. The district's name reflects the nearby St. Nicholas Park.

The James Weldon Johnson Residence is a historic apartment house located at 187 West 135th Street, Harlem, Manhattan, New York City, New York. It is here where James Weldon Johnson (1871-1938) lived from 1925 until his death. In addition to being a composer, songwriter, and author, he was an outspoken advocate for civil rights, working in various roles at the NAACP, including as its General Secretary during his residency here. The building was declared a National Historic Landmark in 1976.

The Dark Tower was a townhouse on 108 West 136th Street in Harlem.

Florence Mills House is a house at 220 West 135th Street in Harlem, Manhattan, New York City. The house was originally believed to be the residence of Florence Mills, a leading African-American actress and entertainer during the 1920s. She lived at this address, or a similar address a few blocks away, during her most productive years from 1910 to 1927. The 220 West 135th Street building that existed in 1927 no longer stands and has been replaced. The site was designated a National Historic Landmark in 1976.The designation was withdrawn in January 2009. The actual address of her home was 220 West 133rd Street; the mistake was perpetuated because a photo of the house was mislabelled as being on West 135th Street in a New York Evening Journal article at the time of her death. The 220 West 133rd Street building has also been demolished and replaced. The mistake in landmarking the West 135th Street address is acknowledged implicitly by the National Park Service, in stating that "For a number of years, this four-story row house was thought to be Mills home for most of her tragically short life."

Smalls Paradise (often called Small's Paradise and Smalls' Paradise, and not to be confused with Smalls Jazz Club), was a nightclub in Harlem, New York City. Located in the basement of 2294 Seventh Avenue at 134th Street, it opened in 1925 and was owned by Ed Smalls (né Edwin Alexander Smalls; 1882–1976). At the time of the Harlem Renaissance, Smalls Paradise was the only one of the well-known Harlem night clubs to be owned by an African-American and integrated. Other major Harlem night clubs admitted only white patrons unless the person was an African-American celebrity. The entertainment at Smalls Paradise was not limited to the stage; waiters danced the Charleston or roller-skated as they delivered orders to customers. Waiters were also known to vocalize during the club's floor shows. Unlike most of the Harlem clubs which closed between 3 and 4 am, Smalls was open all night, offering a breakfast dance which featured a full floor show beginning at 6 am. After 23 years as the owner of the night club, Ed Smalls sold the club to Tommy Smalls (no relation) in 1955. It was later owned by Harlem businessman Pete McDougal and Wilt Chamberlain, and renamed Big Wilt's Smalls Paradise. Many well known musicians, both white and African-American, appeared at the club over the years and often came to Smalls after their evening engagements to jam with the Smalls Paradise band. The club was responsible for promoting popular dances such as the Charleston, the Madison and the Twist. Smalls Paradise was the longest-operating club in Harlem before it closed in 1986. The building has been the site of Thurgood Marshall Academy since 2004.

The Schomburg Center for Research in Black Culture is a research library of the New York Public Library (NYPL) and an archive repository for information on people of African descent worldwide. Located at 515 Malcolm X Boulevard (Lenox Avenue) between West 135th and 136th Streets in the Harlem neighborhood of Manhattan, New York City, it has, almost from its inception, been an integral part of the Harlem community. It is named for Afro-Puerto Rican scholar Arturo Alfonso Schomburg. The resources of the center are broken up into five divisions, the Art and Artifacts Division, the Jean Blackwell Hutson General Research and Reference Division, the Manuscripts, Archives and Rare Books Division, the Moving Image and Recorded Sound Division, and the Photographs and Prints Division. In addition to research services, the center hosts readings, discussions, art exhibitions, and theatrical events. It is open to the general public.

Thurgood Marshall Academy for Learning and Social Change is a public middle and high school in New York City serving grades 6 to 12. It is named for United States Supreme Court Justice Thurgood Marshall. The school is at 200-214 W 135th Street in Harlem. The school opened in 1993 with Harriet Pitts as principal.The school's student body is 70 percent African American and 26 percent Hispanic. About 70 percent are from economically disadvantaged families.After moving four times in its first 11 years, it moved into a new $38 million 6-story 90,000 square foot school building in 2004. Thurgood Marshall's wife Cecilia Marshall was among the dignitaries to attend opening ceremonies for the new school building.Calvin Butts III and the Abyssinian Development Corporation (ADC) were involved in founding the school.Retailer Burlington helped fund a 2017 renovation of the school's library. In 2017, a teacher at the school was charged with assault after allegedly grabbing a 17-year-old female student by the neck.

The Church of St. Charles Borromeo is a parish in the Archdiocese of New York, located at 211 West 141st Street in Manhattan, New York City. It was part of the Harlem Vicariate. The parish was established in 1888.On May 8, 2015, the parish was merged with that of All Saints Church.

The Harlem YMCA is located at 180 West 135th Street between Lenox Avenue and Adam Clayton Powell Jr. Boulevard in the Harlem neighborhood of Manhattan, New York City. Built in 1931-32, the red-brown brick building with neo-Georgian details was designed by the Architectural Bureau of the National Council of the YMCA, with James C. Mackenzie Jr. as the architect in charge. It replaced the building from 1919 across the street. Inside the building is a mural by Aaron Douglas titled "Evolution of Negro Dance." The building was declared a National Historic Landmark in 1976, and was designated a New York City Landmark in 1998.