San Juan River Bridge

Santa Mesa is a district in Manila, Philippines. It is surrounded by Pasig River on the southwestern side, and by the San Juan River on its southern and eastern side. Land borders include the districts of San Miguel to the west and Sampaloc to the north; and to the northeast is Quezon City. Santa Mesa was formerly a part of the Sampaloc district, from which it was partitioned and separated after it had its own parish in 1911. The parish is now known as Old Sta. Mesa (Poblacion), which extends from Victorino Mapa Street to Magsaysay Boulevard. (formerly known as Santa Mesa Boulevard and Calle Santa Mesa)

V. Mapa station is a station on the Manila Light Rail Transit System Line 2. It is one of the many elevated stations that can be found on the line and also one of the four stations in the line with a reserve track nearby (in front of the UERMMC) together with Santolan, Anonas and Araneta Center–Cubao. The station during its inception was formerly called as "G. Araneta Station" but was renamed into the current name due to the minor realignment of some stations (the other being Betty Go-Belmonte) that has caused the change of proximity to the V. Mapa Street. The station serves the areas of Santa Mesa, Manila, Quezon City, and San Juan. The station is located at Ramon Magsaysay Boulevard, near its intersection with Victorino Mapa Street in Santa Mesa, Manila. The station is the tenth station for trains headed to Recto and the fourth station for trains headed to Antipolo. The station has a standard layout, with a concourse level and a platform level. The concourse is below the platform, with stairs, escalators, and elevators leading up to the platform level. The levels are separated by fare gates. The station is also sometimes referred to as Santa Mesa Station. It is named after its location near the junction with V. Mapa Street, which was in turn named after Victorino Mapa, the second Chief Justice of the Supreme Court of the Philippines.

Unciano Colleges (UC), Inc. is a private school with branches in Sta. Mesa, Manila and in Antipolo. The institution is known for its medical science programs and is affiliated the Unciano Colleges and General Hospital in Manila (45years). The Antipolo campus has been providing tertiary education for 29 years now. It provides undergraduate courses in Medical Technology, Nursing, Physical Therapy, and Radiologic Technology. Aside from these allied health courses, the campus also has a Hospitality and Tourism Management department with BS Hotel and Restaurant Management and BS Tourism Management. Additionally, the school currently offers basic education, including Senior High School (SHS). Interested SHS students have the option of choosing between the ABM strand and the STEM strand.

The Central Colleges of the Philippines, Inc. (Filipino: Sentral Kolehiyo ng Pilipinas) also known as CCP is a coeducational educational institution located in Doña Imelda, Quezon City, Metro Manila, Philippines. Formerly known as the Polytechnic Colleges of the Philippines, Inc. (PCP), CCP was established on January 18, 1954, with an enrollment of 300 students. CCP has eleven academic programs or colleges at present.

Victorino Mapa Street, also known by its short form V. Mapa Street, is the main north–south road in the district of Santa Mesa in Manila, Philippines. The street, including its eastern extension, runs for 1.6 kilometers (0.99 mi) from the junction with Magsaysay Boulevard in the north to Pat Antonio Street in the southeast by the San Juan River that serves as the district's border with San Juan and Mandaluyong. It is home to Don Bosco School, Manila, Unciano Colleges and General Hospital, and several new condominiums and a few motels. A portion of the street forms part of Radial Road 5 (R-5) of Manila's arterial road network where it links with Padre Sanchez Street (named after Jesuit priest Francisco de Paula Sanchez from the Ateneo Municipal de Manila) and eventually connects to Shaw Boulevard in Mandaluyong. It is served by V. Mapa LRT Station along Magsaysay Boulevard. Its section from its northern terminus at Magsaysay Boulevard to Valenzuela Street is designated as part of National Route 183 (N183), while its section from Valenzuela Street to P. Sanchez Street is designated as part of National Route 141 (N141); both numbered routes are part of the Philippine highway system. The rest of the route up to Pat Antonio Street is an unnumbered street.

Immaculate Heart of Mary College is a private, Filipino Catholic school administered by the Philippine Province of the Daughters of Charity of St. Vincent De Paul in Quezon City. It was established in June 1949. The school offers Preschool, Primary and Secondary Education for boys and girls (Coed).

Don Bosco School Manila (full school name: Don Bosco School (Salesian Sisters), Inc. - Manila, also known as DBS), is an educational institution owned and operated by the Daughters of Mary Help of Christians (FMA) in the National Capital Region of the Philippines. Established in 1989, Don Bosco School Manila offers co-educational education for primary (elementary) and secondary education (high-school and senior high school). Don Bosco School also offers night school (Alternative Learning System).

The Philippine Chung Hua School (PCHS) is located at 3217 Reposo Street, Santa Mesa, Manila, Philippines. The school teaches Chinese and Filipino, as well as English.

The Battle of Manila (Filipino: Labanan sa Maynila; Spanish: Batalla de Manila), the first and largest battle of the Philippine–American War, was fought on February 4–5, 1899, between 19,000 American soldiers and 15,000 Filipino armed militiamen. Armed conflict broke out when American troops, under orders to turn away insurgents from their encampment, fired upon an encroaching group of Filipinos. Philippine President Emilio Aguinaldo attempted to broker a ceasefire, but American General Elwell Stephen Otis rejected it and fighting escalated the next day. It ended in an American victory, although minor skirmishes continued for several days afterward.

Regina Apostolorum Academy is a private non-sectarian school located in Santa Mesa, Manila,.The school's name is named after their Queen of Apostles. The school was formerly known as Angelicum School. The director of the school is the Ms. Teresa Tuason and the principal is Ms. Janette Liwanag.

Our Lady of Lourdes Hospital (abbreviated as OLLH) is a private non-profit tertiary hospital with 230-bed capacity located in Santa Mesa, Manila, in the Philippines. It is a part of the East Manila Hospital Managers Corporation, a subsidiary of Metro Pacific Investments Corporation. Our Lady of Lourdes Hospital was founded in 1958 by the Missionary Sisters Servants of the Holy Spirit congregation through Our Lady of Lourdes Hospital Inc., a non-stock, non-profit corporation. The hospital is currently managed by Metro Pacific Investments Corporation after the OLLHI agreed on a 20-year lease starting on November 2010.

St. John the Baptist Catholic School, formerly Holy Child Parochial School (1963–2005) is an institution owned and administered by the Archdiocese of Manila, under the Manila Archdiocesan and Parochial Schools Association System, run by the St. John the Baptist Parish, the parish priest and the school director.