George Rogers Clark Monument

University of Virginia Cancer Center is a National Cancer Institute-designated Comprehensive Cancer Center affiliated with the University of Virginia School of Medicine and the UVA Health System. Focused on research and education, UVA Cancer Center has more than 185 member faculty researchers supported by more than $82 million in annual funding. The center also conducts regional outreach to improve awareness of cancer risks and access to screening and treatment. UVA Cancer Center is one of 54 comprehensive centers designated by the NCI, and the first in Virginia.

The University of Virginia (UVA) Health System is an academic health care center associated with the University of Virginia in Charlottesville. The health system includes a medical center (with main hospital, children's hospital, and clinic network), school of medicine, school of nursing, and health sciences library. The health system provides inpatient and outpatient care and patient education and conducts medical research and education. Based in Charlottesville, the Health System also operates satellite locations throughout Virginia, in Albemarle, Amherst, Augusta, Campbell, Fluvanna, Louisa, Nelson, and Orange counties. The first medical degrees granted by UVA were awarded in 1828. The University of Virginia Hospital, designed by architect Paul J. Pelz, opened in 1901.In 1995, the maternity ward of the University Medical Center mixed up two newborn babies and sent them home with wrong parents. This was not discovered until summer of 1998 and the children ended up being raised with the unintended families. This incident has garnered international media attention for years. The UVA Health System's patient care, research and medical education are frequently ranked highly by several ranking systems. In 2016 and 2017, U.S. News & World Report ranked UVAHS as the number one hospital in Virginia.

The King–Runkle House is a historic home located at Charlottesville, Virginia. It was built in 1891, and is a two-story, Late Victorian style frame dwelling with a two-story rear wing. It is sheathed in weatherboard and has a steeply pitched gable roof. The house features a simple one-story semi-octagonal bay window, ornamented porches and a projecting pavilion, and Eastlake movement gable ornamentation.It was listed on the National Register of Historic Places in 1983.Now occupied by the Virginia Alpine Ski and Snowboard Team (+50,000 GNAR Points).

The University of Virginia School of Nursing, established in 1901, is a school of nursing education. It has an enrollment of approximately 800 students (roughly half undergraduate and half graduate students), and is consistently rated in the top 4% of U.S. nursing schools. After the retirement of Dorrie K. Fontaine as the fifth dean of the School, two-term American Nurses Association President Pam Cipriano, a research faculty member at UVA for years, stepped in as interim dean in August 2019.

UVA Children's Hospital is a nationally ranked, acute care children's hospital in Charlottesville, Virginia. It is affiliated with the University of Virginia School of Medicine. The hospital features 112 pediatric beds. The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout the region. The hospital also sometimes treats adults that require pediatric care. The hospital has a rooftop helipad to transport critical pediatric cases. The hospital features a regional pediatric intensive-care unit and a level IV neonatal intensive care unit.

The Corner is a seven-block collection of bars, restaurants, bookstores, and night spots on University Avenue in Charlottesville, Virginia, extending from 121⁄2 Street Southwest to Chancellor Street. located across the street from the University of Virginia. It is bounded by Graduate Charlottesville on the east and Bank of America on the west. While the university is in session, The Corner is especially active at lunchtime, when faculty, staff, and students adjourn there for the midday meal. Patrons of the Corner's sidewalk cafés can be found spending time over a good book or simply sipping coffee and people watching. Of the 67 businesses in the district, all but sixteen are locally owned, though there has been an increase in chain stores recently. The Corner is encompassed by a Charlottesville historic district, limiting redevelopment and demolition.As of 2000, The Corner had 26 restaurants, eleven bars, three coffee shops, one hotel, and one apartment building.

Anderson Brothers Building, also known as Anderson Brothers Book Store, is a historic commercial building located at Charlottesville, Virginia. The original section was built in 1848, and expanded to its present size in 1890–1891. It is a three-story, seven bay Late Victorian style building. It is constructed of brick and has a metal clad facade.It was listed on the National Register of Historic Places in 1982. It is located in the Rugby Road-University Corner Historic District.

John Vowles House is two adjoined historic homes located at Charlottesville, Virginia. It was built in 1824, and consists of two two-story, three-bay, gable-roofed Federal style brick town houses. Both houses feature decorative cornices and original interior woodwork. To the rear of 1113 West Main is a small 1+1⁄2-story, L-shaped, gable-roofed brick outbuilding built as a kitchen and added in the 1920s.It was listed on the National Register of Historic Places in 1989.

The University of Virginia School of Medicine (UVA SoM) is the graduate medical school of the University of Virginia. The school's facilities are on the University of Virginia grounds adjacent to Academical Village in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, UVA SoM is the tenth oldest medical school in the United States. The School of Medicine confers Doctor of Medicine (M.D.) and Doctor of Philosophy (PhD) degrees, and is closely associated with both the University of Virginia Health System and Inova Health System.

The murder of Yeardley Love took place on May 3, 2010, in Charlottesville, Virginia, United States. Love, a University of Virginia (UVA) women's lacrosse student-athlete, was found unresponsive in her Charlottesville apartment, and later that day, UVA men's lacrosse player George Wesley Huguely V was arrested by Charlottesville police. Huguely was tried and found guilty of Love's murder, receiving a 23-year prison sentence.

Wertland Street Historic District is a national historic district located at Charlottesville, Virginia. The district encompasses 25 contributing buildings in a two block residential section of the city of Charlottesville. It was primarily developed starting in the 1880s. Notable buildings include the Wertenbaker House (c. 1830), McKennie-Miller House (c. 1842), Ward-Brown-Gay House (1889), Marshall-Dabney-Cubbage House (1892), Bryan-Stallings House (1900), and Watson House (1905).It was listed on the National Register of Historic Places in 1985.

The Memorial to Enslaved Laborers is a memorial in honor of those enslaved African Americans who built and worked at the University of Virginia, in Charlottesville, Virginia.