Park and Tilford Building

Sylvia's Restaurant of Harlem, often called Sylvia's Soul Food or just Sylvia's, is a soul food restaurant located at 328 Lenox Avenue, between 126th and 127th Streets, in Harlem, Manhattan, New York City. It was founded in 1962 by Sylvia Woods. It has since expanded to a much larger space at its present location, and an adjacent building. The restaurant also sells a line of prepared foods, beauty and skin care items, cookbooks, and a children's book written by Woods. Woods purchased the original luncheonette by borrowing money from her mother, who had to mortgage her farm to provide it. The restaurant attracts a clientele that ranges from Harlem locals to visiting celebrities. Whoopi Goldberg, Bill Clinton, Nelson Mandela, Caroline Kennedy, Jesse Jackson, Al Sharpton, Magic Johnson, Barack Obama, Bernie Sanders and Bruno Mars are among those who have dined there. Sylvia's was also featured on a Manhattan-themed episode of the Travel Channel's Man v. Food in early 2009. On September 19, 2007, commentator Bill O'Reilly received criticism regarding comments he made on his syndicated radio show, about having lunch at Sylvia's with Al Sharpton. O'Reilly concluded that stereotypes regarding African Americans were not true based on observations he had made at the restaurant.In response to the COVID-19 pandemic, Sylvia's Restaurant participated in relief efforts by donating fifty meals to Harlem Hospital. The restaurant announced plans to open a pop-up pantry featuring meal kits to serve the community.

Lenox Lounge was a long-standing bar in Harlem, New York City. It was located in 288 Lenox Avenue, between 124th and 125th. The bar was founded in 1939 by Ralph Greco and served as a venue for performances by many great jazz artists, including Billie Holiday, Miles Davis, and John Coltrane. Harlem Renaissance writers James Baldwin and Langston Hughes were both patrons, as was Malcolm X.The bar deteriorated through the middle of the 20th century. Alvin Reid, Sr. purchased it in 1988 and restored the original Art Deco interior from September 1999 to March 2000, during the only closure in the bar's history.The Lenox Lounge was voted "Best of the Best" by the 2002 Zagat Survey Nightlife Guide and by the 2001 New York Magazine. In 2012, a rent increase threatened to shutter the establishment. In December 2012, it was announced that it would close at the end of the year. However in January 2013 Reid said he was reopening at 333 Lenox Avenue and that it would have its iconic neon sign there. Richard Notar, who owned the Nobu Restaurant chain and who took over the lease on the original 288 Lenox location, said he would maintain the decor of the original 288 lounge which does not yet have a name. In May 2017 the building was demolished. The Zebra Room was used for a key scene in the Mad Men pilot, "Smoke Gets In Your Eyes".

The 125th Street station is a station on the IRT Lenox Avenue Line of the New York City Subway. Located at the intersection of 125th Street (also known as Dr. Martin Luther King Jr Boulevard) and Lenox Avenue (also known as Malcolm X Boulevard) in Harlem, it is served by the 2 and 3 trains at all times. The 125th Street station was constructed for the Interborough Rapid Transit Company (IRT) as part of the city's first subway line, which was approved in 1900. Construction on the tunnel segment that includes the 125th Street station started on October 2 of the same year. The station opened on November 23, 1904. The station platforms were lengthened in 1910. The 125th Street station contains two side platforms and two tracks. The station was built with tile and mosaic decorations. The platforms contain exits to Lenox Avenue's intersection with 125th Street and are not connected to each other within fare control.

Rice High School was a private, Roman Catholic, college preparatory high school in the Harlem neighborhood of New York City, United States. It is located within the Roman Catholic Archdiocese of New York. The school closed in 2011 due to financial difficulties.

ATLAH World Missionary Church (formerly Bethelite Missionary Baptist Church) is a Christian church and ministry located in Harlem, New York. James David Manning is the chief pastor. The church campus is the site of the unaccredited ATLAH Theological Seminary, where classes are offered on preaching and prophecy. The church also has a studio that Manning uses for his Internet radio program The Manning Report. The church's YouTube channel had over 72,000 subscribers as of March 2018 but was shut down by YouTube later that year.

The Frederick Douglass Book Center served as a bookshop and meeting place for the minorities of New York City. The center contained literature that specialized in African, Afro-American, and Caribbean history and culture. The center remained in Harlem until it was torn down in 1968.

Greater Bethel AME Church is located at 32 West 123rd Street in Harlem. It is one of the oldest black churches in New York City. The Greater Bethel African Methodist Episcopal Church was founded in Lower Manhattan in 1819 and moved into the Harlem Library building in the early twentieth century. Edgar K. Bourne, architect of this limestone and brick building constructed from 1891–1892, was also a member of the library's board of trustees. The church moved into the structure on West 123rd Street when the Harlem Library was moved to 9-11 West 124th Street after being added to the New York Public Library system in 1901. Greater Bethel is within the Mount Morris Park historic district and as such is a designated New York City Landmark.

St. Andrew's Episcopal Church is a historic Episcopal church located at 2067 Fifth Avenue at 127th Street in the neighborhood of Harlem in Manhattan, New York City. Built in 1872, it was designed by noted New York City architect Henry M. Congdon (1834–1922) in the Gothic Revival style. It features a 125 foot tall clock tower surmounted by a slate covered spire surrounded by four towerlets.On March 18, 1980, it was added to the National Register of Historic Places. The church was designated as a city landmark by the New York City Landmarks Preservation Commission in 1967. It is still an active parish in the Episcopal Diocese of New York.In 2020, it reported 138 members, average attendance of 32, and $192,540 in plate and pledge income.

The Studio Museum in Harlem is an American art museum devoted to the work of artists of African descent. The museum's galleries are currently closed in preparation for a building project that will replace the current building, located at 144 West 125th Street between Adam Clayton Powell Jr. Boulevard and Lenox Avenue in Harlem, Manhattan, New York City, with a new one on the same site. Founded in 1968, the museum collects, preserves and interprets art created by African Americans, members of the African diaspora, and artists from the African continent. Its scope includes exhibitions, artists-in-residence programs, educational and public programming, and a permanent collection. Since opening in a rented loft at Fifth Avenue and 125th Street, the Studio Museum has earned recognition for its role in promoting the works of artists of African descent. The museum's Artist-in-Residence program has supported over one hundred graduates who have gone on to highly regarded careers. A wide variety of educational and public programs include lectures, dialogues, panel discussions and performances, as well as interpretive programs, both on- and off-site, for students and teachers. The exhibitions program has also expanded the scope of art historical literature through the production of scholarly catalogues, brochures, and pamphlets.

The Frequency Exhibition was a contemporary exhibition at the Studio Museum in Harlem from November 9, 2005 - March 12, 2006. Curated by Thelma Golden and associate curator Christine Y. Kim, the exhibition featured the works of 35 emerging Black artists. Frequency, following the 2001 exhibition "Freestyle," is one of five "F" themed exhibitions alongside Flow, Fore, and Fictions. While curators Golden and Kim point out that Frequency was not "Freestyle II," the organization of artists under the umbrella of Black identity engages with "Post-Black" art similarly to the Freestyle exhibition.

Sushi Inoue is a Japanese restaurant in New York City. The restaurant has received a Michelin star.

The Adam Clayton Powell Jr. State Office Building, originally the Harlem State Office Building, is a nineteen-story, high-rise office building located at 163 West 125th Street at the corner of Adam Clayton Powell Jr. Boulevard in the Harlem neighborhood of Manhattan, New York City. It is named after Adam Clayton Powell Jr, the first African-American elected to Congress from New York. It was designed by the African-American architecture firm of Ifill Johnson Hanchard in the shape of an African mask in the Brutalist style. It is the tallest building in Harlem, overtaking the nearby Hotel Theresa.