Hollenden Hotel

Fifth Third Center is a skyscraper located in downtown Cleveland, Ohio along Superior Avenue. The building has 27 stories and rises to a height of 446 ft (136 m) with 515,000 square feet (47,800 m2). It is currently the sixth tallest building in Cleveland. It was designed by RTKL Associates and was originally constructed as Bank One Center in 1991. It was renamed in 2003, when Fifth Third Bank of Cincinnati relocated to the structure.

The Leader Building is a 15-story high-rise building located at the southwest corner of Superior Avenue and East 6th Street in Downtown Cleveland's Historic Gateway District. Completed in 1913, the 199-foot (61 m), 322,600-square-foot (29,970 m2) building was built by industrialist Dan Hanna to house The Cleveland Leader, a Cleveland newspaper he had recently acquired.The limestone-clad building was designed by architect Charles Adams Platt in the Beaux-Arts style, and features high-quality interior materials. The Leader Building was also home to the Cleveland News, which Hanna also owned. While The Cleveland Leader closed in 1917, the News continued to occupy a portion of the Leader Building until 1926. Its upper stories were rented out as office space, and were popular among lawyers. For 60 years, the building's basement was home to the Colonnade Cafeteria.In 2014, the K & D Group acquired the building for $5.4 million. At the time of the purchase, the Leader Building was operated as office space, and had a 60% occupancy rate. The K & D Group announced plans for a mixed-use renovation, and said they would convert a portion of the building to apartments. When the renovations were completed in 2017, the company had converted the top 12 floors to apartments they named the Residences at the Leader. The ground floor remained as retail space and the second and third floors remained as offices.

The Federal Reserve Bank of Cleveland is the Cleveland-based headquarters of the U.S. Federal Reserve System's Fourth District. The district is composed of Ohio, western Pennsylvania, eastern Kentucky, and the northern panhandle of West Virginia. It has branch offices in Cincinnati and Pittsburgh. The check processing center in Columbus, Ohio, was closed in 2005. The chief executive officer and president is Loretta Mester.The bank building is a 13-story 203 foot high-rise, located at Superior Avenue and East 6th Street in downtown Cleveland. It was designed by the Cleveland firm of Walker and Weeks and completed in 1923. Its exterior architecture emulates an Italian Renaissance palazzo, and is clad in Georgia pink marble. An extension to the building designed by HOK was completed in 1998, providing new facilities for check processing and cash handling. The building is listed on the National Register of Historic Places. The building's entrances feature allegorical sculptures by Henry Hering representing Security and Integrity flanking the East Sixth Street entrance, while his Energy watches the Superior Avenue entry. Its original 100 short tons (91 t) bank vault door is the largest in the world and was designed by Frederick S. Holmes. The door casting itself was 20 short tons (18 t). It incorporates the largest hinge ever built. The hinge has an overall height of 19 feet (5.8 m) and weighs over 47 short tons (43 t) fully assembled. The vault's use was discontinued in 1997, though it is preserved intact for posterity.

The Superior Building, originally known as the Cleveland Discount Building, is a high-rise building in Cleveland, Ohio. The building rises 265 feet (81 m) in Downtown Cleveland. It contains 22 floors, and was completed in 1922. The Superior Building currently stands as the 28th-tallest building in the city. The architectural firm who designed the building was Walker & Weeks. The building's design incorporates a set of Doric columns in its base.The Superior Building was one of the earliest skyscrapers to be completed in Cleveland. However, it never stood as the tallest structure in the city; the Keith Building, also completed in 1922, rose only 7 feet (2.1 m) taller, and thus captured the title of tallest building in Cleveland. The Superior Building was added to the National Register of Historic Places in 1991.

AmTrust Financial Building, formerly known as McDonald Investment Center, Key Center and the Central National Bank Building, is a commercial high-rise building in Cleveland, Ohio. The building rises 308 feet (94 m) in Downtown Cleveland. It contains 23 floors, and was completed in 1969. The building currently stands as the 18th-tallest building in the city. When first constructed, the tower stood as the 5th-tallest building in Cleveland. The architect who designed the building was Charles Luckman.

The Beacon is a luxury, residential skyscraper in downtown Cleveland that began construction at 515 Euclid Avenue in late 2017 and was completed in late 2019. The tower rises 350 feet (110 m) tall, with approval from the city council to exceed the city's 250 feet (76 m) limit. The Beacon sits at 29 floors; 8 floors of parking garage, 19 floors of one and two bedroom residential suites and rooftop lounge.Part of the need for the tower is due to the two decade old resurgence of interest in downtown Cleveland. Residential population has up ticked, spearheaded by a 77% increase of new housing units and 95% occupancy rate from 2000 to 2015. This surge in residential growth has seen nearly 15,000 people living in the Cleveland neighborhood as of 2017. That makes downtown Cleveland the largest populated downtown in Ohio (far ahead of Columbus, Cincinnati, and Akron) which illustrates the need for more housing capacity in the central location of Cleveland. It is the third-tallest residential building in the city behind the Terminal Tower, which is slated to be converted into apartments, and The 9 Cleveland.

The Garfield Building is a high-rise building on the corner of Euclid Avenue and E. 6th Street in Cleveland, Ohio, in the United States. It was the first steel frame skyscraper constructed in the city.

The Guardian Bank Building (originally known as the New England Building and later known as the National City Bank Building) is a high-rise building on Euclid Avenue in downtown Cleveland, Ohio.

The Arcade in downtown Cleveland, Ohio, is a Victorian-era structure of two nine-story buildings, joined by a five-story arcade with a glass skylight spanning over 300 feet (91 m), along the four balconies. Erected in 1890, at a cost of $867,000 ($26,100,000 in 2021 dollars), the Arcade opened on Memorial Day (May 30, 1890), and is identified as one of the earliest indoor shopping arcades in the United States. The Arcade was modified in 1939, remodeling the Euclid Avenue entrance and adding some structural support. It was designated a National Historic Landmark in 1975.

The Cathedral of St. John the Evangelist (commonly referred to locally as St. John's Cathedral) is a historic Roman Catholic church building located at 1007 Superior Avenue in Cleveland, Ohio, in the United States. Completed and consecrated in 1852, it is the cathedral of the Roman Catholic Diocese of Cleveland. Numerous renovations have enlarged and changed some aspects of the cathedral, but it remains essentially the same since its construction.

St. John's College in Cleveland, Ohio, originally known as Sisters' College, was a school for teachers and nurses established in 1928 by the Roman Catholic Diocese of Cleveland. In fall 1974, enrollment included 619 women and 51 men. The school closed in 1975. The facilities were then merged with the adjacent St. John's Cathedral. A school of the same name in Cleveland was founded by Bishop Louis Rappe in 1854.Notable alumni include Judy Robson, Majority Leader of the Wisconsin State Senate (2007-), Michael Pennock (1945-2009), Catholic author.

Cleveland Public Library, located in Cleveland, Ohio, operates the Main Library on Superior Avenue in downtown Cleveland, 27 branches throughout the city, a mobile library, a Public Administration Library in City Hall, and the Ohio Library for the Blind and Physically Disabled. The library replaced the State Library of Ohio as the location for the Ohio Center for the Book in 2003.