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The Brill Building is an office building at 1619 Broadway on 49th Street in the New York City borough of Manhattan, just north of Times Square and further uptown from the historic musical Tin Pan Alley neighborhood. It was built in 1931 as the Alan E. Lefcourt Building, after the son of its builder Abraham E. Lefcourt, and designed by Victor Bark Jr. The building is 11 stories high and has approximately 175,000 square feet (16,300 m2) of rentable area. The Brill Building is famous for housing music industry offices and studios where some of the most popular American songs were written. It is considered to have been the center of the American music industry that dominated the pop charts in the early 1960s. The "Brill" name comes from a haberdasher who operated a store at street level and subsequently bought the building. The Brill Building was purchased by 1619 Broadway Realty LLC in June 2013 and underwent renovation during the 2010s. A CVS Pharmacy opened on the first two floors of the building in 2019.

Jack Dempsey's Broadway Restaurant, known popularly as Jack Dempsey's, was a restaurant located in the Brill Building on Broadway between 49th Street and 50th Streets in Manhattan, New York City.Owned by world heavyweight boxing champion Jack Dempsey, the restaurant originally opened for business as Jack Dempsey's Restaurant on Eighth Avenue and 50th Street, directly across from the third Madison Square Garden, in 1935. Most nights would find Dempsey's famous proprietor on hand to greet guests, sign autographs, pose for pictures, and hold court with people from all walks of life. It was next door to Jack J. Amiel's Turf Restaurant on Times Square. Amiel became famous as the owner of the "underdog" horse Count Turf who won the 1951 Kentucky Derby. A few years after his Derby win, Amiel became a co-owner of Jack Dempsey's Restaurant. A favorite attraction of the restaurant was its famous cheesecake. In a letter to New York in 1973, Dempsey wrote, "Jack Dempsey's cheesecake has been in existence for almost 40 years. And in New York it is an institution in itself. It is baked on our premises, eaten in our restaurant, as well as airmailed all over the United States and Europe. We have had requests for our cheesecake from tourists who come to New York from faraway places; we've fulfilled requests over the years from France's late President Charles DeGaulle, who had his cheesecakes sent several times a year."The restaurant closed in 1974.

The Ambassador Theatre is a Broadway theater at 219 West 49th Street in the Theater District of Midtown Manhattan in New York City. Opened in 1921, the Ambassador Theatre was designed by Herbert J. Krapp and was constructed for the Shubert brothers. It has 1,125 seats across two levels and is operated by The Shubert Organization. The auditorium interior is a New York City designated landmark. The theater is oriented on a diagonal axis, maximizing seating capacity on its small site of 100 by 100 feet (30 by 30 m). The facade is largely made of golden brick and is simple in design. The most prominent part of the facade is a curved entrance at the southeast corner, facing Broadway, where a lobby leads to the rear of the theater's orchestra level. The auditorium contains Adam-style detailing, a large balcony, and box seats with decorated arches above them. The auditorium contains a segmental proscenium arch topped by a curved sounding board. The Shuberts developed the Ambassador, along with the neighboring O'Neill and Walter Kerr theaters, after World War I as part of a theatrical complex around 48th and 49th Streets. The Ambassador opened on February 11, 1921, with the musical The Rose Girl. The Shuberts sold the property in 1935, and it was intermittently used as a CBS broadcast studio, a movie theater, and for live theater until 1945. The Ambassador then hosted foreign films in the late 1940s and was a studio for the DuMont Television Network in the early 1950s. In 1956, the Shuberts assumed ownership again, returning it to use as a live theater. Though many of the Ambassador's productions in the 20th century were short runs, it has hosted since 2003 the musical Chicago, the second-longest-running Broadway show as of 2021.

The Theater Center (known as The Snapple Theater Center until 2016) is a multi-theater entertainment complex located on the corner of 50th Street and Broadway in New York City.

The Crowne Plaza Times Square Manhattan (originally the Holiday Inn Crowne Plaza Manhattan) is a hotel at 1601 Broadway, between 48th and 49th Streets, in the Theater District of Midtown Manhattan in New York City. Operated by Intercontinental Hotels Group as part of the Crowne Plaza chain, the hotel has 795 guest units. The hotel was designed by Alan Lapidus and is 480 feet (150 m) tall with 46 floors. The facade was designed in glass and pink granite, with a 100-foot-tall (30 m) arch facing Broadway. The hotel was designed to comply with city regulations that required deep setbacks at the base, as well as large illuminated signs. In addition to the hotel rooms themselves, the Crowne Plaza Times Square contains ground-story retail space, nine stories of office space, and a 159-space parking garage. The hotel's tenants include the American Management Association, Learning Tree International, and the New York Sports Club. Developer William Zeckendorf Jr. bought the hotel's site in 1985 and subsequently razed the existing structures there. Construction commenced in 1988, and the hotel opened on December 1, 1989. For the first several years of the hotel's operation, its office space and exterior signage was empty. Adam Tihany redesigned the interior in 1999. The City Investment Fund, a joint venture between Morgan Stanley Real Estate and Fisher Brothers, bought the Crowne Plaza in 2006 and renovated it again two years later. Vornado Realty Trust then acquired majority ownership of the hotel in 2015. The hotel rooms have been closed since 2020 due to the COVID-19 pandemic in New York City.

Carolines on Broadway is a venue for stand-up comedy located at 750 Seventh Avenue, on Broadway between 49th and 50th Streets, in the Midtown Manhattan neighborhood of New York City.

The 50th Street station is a local station on the IRT Broadway–Seventh Avenue Line of the New York City Subway. Located at the intersection of 50th Street and Broadway at the northwest corner of the Theater District, it is served by the 1 train at all times and by the 2 train during late nights. The 50th Street station was constructed for the Interborough Rapid Transit Company (IRT) as part of the city's first subway line, which was approved in 1900. Construction of the line segment that includes the 50th Street station began on September 19 of the same year. The station opened on October 27, 1904, as one of the original 28 stations of the New York City Subway. The station's platforms have been lengthened since opening. The 50th Street station contains two side platforms and four tracks; express trains use the inner two tracks to bypass the station. The station was built with tile and mosaic decorations. The platforms contain exits to 50th Street and Broadway and are not connected to each other within fare control.

750 Seventh Avenue is a 36-story office building in the Midtown Manhattan neighborhood of New York City. The building was designed by Kevin Roche of Roche-Dinkeloo and developed by David and Jean Solomon. 750 Seventh Avenue occupies a site on the north side of 49th Street between Broadway and Seventh Avenue. Since 1994, the building has mostly been occupied by the offices of financial-services company Morgan Stanley. The building contains a black-glass facade with large signs as well as etched-glass panels. On the upper stories, the exterior has setbacks in a spiral pattern, which terminate in an offset glass pinnacle. Solomon Equities had developed 750 Seventh Avenue as a speculative development in 1989 on the site of the Rivoli Theatre, a movie theater. When the building was completed, it had no tenants until the law firm Olwine, Connelly, Chase, O'Donnell & Wehyer leased space in April 1990. Olwine Connelly disbanded in 1991 without ever paying rent, and the Solomons placed the building into bankruptcy shortly afterward. The building was taken over by a consortium of banks, who leased some space to law firm Mendes & Mount and accounting firm Ernst & Young. Morgan Stanley bought the building in 1994 to supplement its space at nearby 1585 Broadway. Real-estate firm Hines and the General Motors Pension Fund bought 750 Seventh Avenue in 2000 and resold it in 2011 to Fosterlane Management.

The Studebaker Building is a former structure at 1600 Broadway on the northeast corner at 48th Street in Manhattan, New York City. It was erected by the Juilliard Estate, in 1902, between Broadway and 7th Avenue, in the area north of Times Square. It was demolished in 2004 to make room for an apartment tower, a twenty- five story, 136 unit, luxury condominium designed by architect Einhorn Yaffee Prescott.The Studebaker Building was ten stories high and occupied the entire block front between Broadway and 7th, facing Broadway for 113 feet (34 m). It was built from the Juilliard estate, "seeking a thoroughly safe income upon what was doubtless a very modest appraisal of the property's value." The structure covered the southern end of the block at Broadway and 49th Street. It was fireproof and fronted 48th Street for 104 feet (32 m).

The Walter Kerr Theatre, previously the Ritz Theatre, is a Broadway theater at 219 West 48th Street in the Theater District of Midtown Manhattan in New York City. The theater was designed by Herbert J. Krapp and was constructed for the Shubert brothers in 1921. The venue, renamed in 1990 after theatrical critic Walter Kerr, has 975 seats across three levels and is operated by Jujamcyn Theaters. The facade is made of plain patterned brick, with fire escapes in front of it. The auditorium contains Adam-style detailing, two balconies, and murals. The Shuberts developed the Ritz Theatre after World War I as part of a theatrical complex around 48th and 49th Streets. The Ritz Theatre opened on March 21, 1921, with the play Mary Stuart, and it was leased to William Harris Jr., who operated it for a decade. After many unsuccessful shows, the theater was leased to the Works Progress Administration's Federal Theatre Project from 1936 to 1939, then served as a CBS and NBC broadcasting studio. The Ritz briefly hosted legitimate shows in 1942 and 1943, and it again functioned as a studio for ABC until 1965. The Ritz was abandoned for several years until Eddie Bracken took over in 1970, renovating it and hosting several short-lived shows from 1971 to 1973. During the 1970s, the Ritz variously operated as a pornographic theater, vaudeville house, children's theater, and poster-storage warehouse. Jujamcyn took over in 1981 and reopened it two years later following an extensive restoration. The theater was renovated again in 1990 and renamed after Kerr.

The 49th Street station is a local station on the BMT Broadway Line of the New York City Subway. Located at West 49th Street and Seventh Avenue in Midtown Manhattan, it is served by the N train at all times, the R train at all times except late nights, the W train on weekdays, and the Q train during late nights.

St. Malachy Roman Catholic Church is a parish church of the Roman Catholic Archdiocese of New York, located in Manhattan on West 49th Street, between Broadway and Eighth Avenue. The parish has served the theatre community in a special way since 1920, and its parishioners have included many actors, such as Bob Hope and Gregory Peck.