369th Regiment Armory

Harlem River Park is a portion of the Manhattan Waterfront Greenway that runs along the Harlem River from 145th Street south to 135th Street near the 369th Regiment Armory. In 1997, under Rudy Giuliani and NYC Parks Commissioner Stern, the mayor's office provided approximately $380,000 to explore the park's creation and construction began in 2001 to extend the East River Greenway north from the 125th Street terminus in what was, by 2017, called the Harlem Greenway Link.The park includes murals, including ones in tribute to Harlem's cultural history, and preservationists have discussed a so-called "Grand Harlem Park" encompassing this and others adjacent.

The 145th Street Bridge is a four-lane swing bridge across the Harlem River in New York City, connecting 145th Street and Lenox Avenue in Manhattan with 149th Street and River Avenue in the Bronx. The bridge is operated and maintained by the New York City Department of Transportation. Construction on the original 145th Street Bridge began on April 19, 1901, and the $2.75 million bridge was opened to traffic on August 24, 1905. The designer was Alfred Pancoast Boller. It once carried northbound New York State Route 22 and New York State Route 100. This bridge was also once named the "Lenox Avenue Bridge", though that name has fallen into disuse. A new swing span for the bridge was assembled in the Port of Coeymans in Coeymans, New York, in southern Albany County. The span was replaced in early November 2006.The 145th Street Bridge carries the Bx19 bus route operated by MTA New York City Transit. Between 2000 and 2014, the bridge opened for vessels 23 times.

The Cotton Club was a New York City nightclub from 1923 to 1940. It was located on 142nd Street and Lenox Avenue (1923–1936), then briefly in the midtown Theater District (1936–1940). The club operated during the United States' era of Prohibition and Jim Crow era racial segregation. Black people initially could not patronize the Cotton Club, but the venue featured many of the most popular black entertainers of the era, including musicians Fletcher Henderson, Duke Ellington, Jimmie Lunceford, Chick Webb, Louis Armstrong, Count Basie, Fats Waller, Willie Bryant; vocalists Adelaide Hall, Ethel Waters, Cab Calloway, Bessie Smith, Aida Ward, Avon Long, the Dandridge Sisters, the Will Vodery Choir, The Mills Brothers, Nina Mae McKinney, Billie Holiday, Midge Williams, Lena Horne, and dancers such as Katherine Dunham, Bill Robinson, The Nicholas Brothers, Charles 'Honi' Coles, Leonard Reed, Stepin Fetchit, the Berry Brothers, The Four Step Brothers, Jeni Le Gon and Earl Snakehips Tucker. At its prime, the Cotton Club served as a hip meeting spot, with regular "Celebrity Nights" on Sundays featuring guests such as Jimmy Durante, George Gershwin, Sophie Tucker, Paul Robeson, Al Jolson, Mae West, Richard Rodgers, Irving Berlin, Eddie Cantor, Fanny Brice, Langston Hughes, Judy Garland, Moss Hart, and Jimmy Walker, among others.

The Savoy Ballroom was a large ballroom for music and public dancing located at 596 Lenox Avenue, between 140th and 141st Streets in the Harlem neighborhood of Manhattan, New York City. Lenox Avenue was the main thoroughfare through upper Harlem. Poet Langston Hughes calls it the "Heartbeat of Harlem" in Juke Box Love Song, and he set his work "Lenox Avenue: Midnight" on the legendary street. The Savoy was one of many Harlem hot spots along Lenox, but it was the one to be called the "World's Finest Ballroom". It was in operation from March 12, 1926, to July 10, 1958, and as Barbara Englebrecht writes in her article "Swinging at the Savoy", it was "a building, a geographic place, a ballroom, and the 'soul' of a neighborhood". It was opened and owned by white entrepreneur Jay Faggen and Jewish businessman Moe Gale. It was managed by African-American businessman and civic leader Charles Buchanan. Buchanan, who was born in the British West Indies, sought to run a "luxury ballroom to accommodate the many thousands who wished to dance in an atmosphere of tasteful refinement, rather than in the small stuffy halls and the foul smelling, smoke laden cellar nightclubs ..."

The 145th Street station is a station on the IRT Lenox Avenue Line of the New York City Subway. Located at the intersection of 145th Street and Lenox Avenue in Harlem, Manhattan, it is served by the 3 train at all times. Built for the Interborough Rapid Transit Company (IRT), the 145th Street station contains two side platforms that can only fit six and a half train cars, unlike almost all other IRT stations, which are able to fit full-length ten-car trains. The station opened in 1904 as one of the northern termini of the original subway line operated by the IRT. With the construction of the Harlem–148th Street station to the north in the 1960s, the 145th Street station was planned to be closed, but due to community opposition, and passengers' protests, the station remained open. Since the 145th Street station is the second-to-last stop on the line, entry is provided only to the southbound platform, although northbound customers are allowed to exit from this station. The station was added to the National Register of Historic Places in 2005, and was closed from July to November 2018 for extensive renovations. The 145th Street station contains two side platforms and two tracks. The station was built with tile and mosaic decorations. The platforms contain exits to Lenox Avenue's intersection with 145th Street and are not connected to each other within fare control.

The Madison Avenue Bridge is a four-lane swing bridge crossing the Harlem River in New York City, connecting Madison Avenue in Manhattan with East 138th Street in the Bronx. It was designed by Alfred P. Boller and built in 1910, doubling the capacity of an earlier swing bridge built in 1884. The bridge is operated and maintained by the New York City Department of Transportation. For 2011, the NYCDOT reported an average daily traffic volume in both directions of 41,423; having reached a peak of 49,487 in 2002. Between 2000 and 2014, the bridge opened for vessels 69 times.

The Church of St. Mark the Evangelist is a Roman Catholic parish church in the Roman Catholic Archdiocese of New York, located at West 138th Street, near Lenox Avenue in northern Harlem, Manhattan, New York City. The address is 59-61 West 138th Street and 195 East Lenox Avenue. The parish was established in 1907 and has been staffed by the Holy Ghost Fathers since 1912. The Rev. Charles J. Plunkett, pastor, had a brick church built in 1914 to designs by Nicholas Serracino of 1170 Broadway for $12,000.

The Riverton Houses is a large (originally 1,232 unit) residential development in Harlem, Manhattan, New York City.

Harlem Hospital School of Nursing was a training school for African-American women, which was established at Harlem Hospital in Harlem, New York City in 1923. It was founded due to the lack of nursing schools in New York that accepted African American women. Until 1923, the Lincoln Hospital School for Nurses in The Bronx was the only school that allowed the enrollment of Black women. When Mayor Hylan sought reelection in 1921, the NAACP and other community organizations lobbied the mayor to improve healthcare access. Around the same time, Lurline Vassall of Brooklyn, was denied entry to the Bellevue Hospital School of Nursing because of her race. Lurline's father William Vassall launched a campaign to open a school for black nurses. In response, Hylan's administration supported the creation of the Harlem Hospital School of Nursing.The school opened on January 3, 1923, with a class of twenty black women. It was a two and a half year program.The Harlem Hospital School of Nursing closed in 1977.

Bronx Terminal Market, formerly known as Gateway Center at Bronx Terminal Market, is a shopping mall along the Major Deegan Expressway in Concourse, Bronx, New York. The center encompasses just under one million square feet of retail space built on a 17-acre (69,000 m2) site that formerly held a wholesale fruit and vegetable market (also named the Bronx Terminal Market) as well as the former Bronx House of Detention, south of Yankee Stadium. The US$500 million shopping center, which was completed in 2009, saw the construction of new buildings and two smaller buildings, one new and the other a renovation of an existing building that was part of the original market. The two main buildings are linked by a six-level garage for 2,600 cars. The center's design has earned a Leadership in Energy and Environmental Design (LEED) Silver award.

The Greater Hood Memorial AME Zion Church was the first black church in Harlem, New York. It now receives notoriety as the "Oldest Continuing" church in Harlem. The church’s first house of worship was erected on East 117th Street, between 2nd and 3rd Avenues in 1843.

Mill Pond Park is a public park in the New York City borough of the Bronx. It was built to compensate for the loss of parkland resulting from the construction of new Yankee Stadium between 2006 and 2009. The park's name was inspired by a dam near the site of a creek that emptied into the Harlem River.