10 East 40th Street

Wood Tobé–Coburn School was a private for-profit career college in New York City. It closed in 2017.

The Stavros Niarchos Foundation Library (SNFL), popularly known as the Mid-Manhattan Library, is a branch of the New York Public Library (NYPL) at the southeast corner of 40th Street and Fifth Avenue in the Midtown Manhattan neighborhood of New York City. It is diagonally across from the NYPL's Main Branch and Bryant Park to the northwest. The Stavros Niarchos Foundation Library has space for 400,000 volumes across a basement and seven above-ground stories. Its design includes 11,000 square feet (1,000 m2) of event space and 1,500 seats for library users. The Mid-Manhattan Library opened in 1970 to house the circulating collection formerly located in the NYPL's Main Branch. The branch moved to its current building, a former Arnold Constable & Company department store, in 1981. After a failed attempt to close the Mid-Manhattan Library in the 2010s, the NYPL announced a major renovation of the branch in 2014. Between 2017 and 2020, the branch was closed for renovations funded by the Stavros Niarchos Foundation, and the library was renamed after the foundation.

461 Fifth Avenue is a 28-story skyscraper in Midtown Manhattan, New York City, at the northeast corner of Fifth Avenue and 40th Street. The building was constructed in 1988 by the Mitsui Fudosan development group and designed by Skidmore, Owings & Merrill.

Eurasia Group is a political risk consultancy founded in 1998 by Ian Bremmer.

The Macbeth Gallery was an art gallery in New York City that was the first to specialize in American art. Founded by William Macbeth in 1892, the gallery gained notoriety in 1908 when it put on an exhibition protesting the restrictive policies and conservative tastes of the existing art establishment in New York, exemplified by the National Academy of Design. The exhibition showcased the work of eight artists who were known for portraying gritty scenes of daily life, especially of poorer communities in New York: Robert Henri, William Glackens, George Luks, Everett Shinn, John Sloan, Arthur Bowen Davies, Ernest Lawson, and Maurice Prendergast. Though they had varying styles, the artists were later known collectively as "The Eight". Henri, Glackens, Luks, Shinn, and Sloan were associated with the Ashcan School, and the 1908 exhibition brought increased national attention to that movement and founded their reputations.In 1948, Andrew Wyeth's painting Christina's World was first exhibited at the Macbeth Gallery before it was purchased by the Museum of Modern Art.As the art scene in New York shifted towards abstract expressionism in the early 1950s, the gallery, which had focused on American Realism and Impressionism, started to fall out of favor. Macbeth celebrated its sixtieth anniversary with a group exhibition in April 1952 before closing its doors in 1953.

425 Fifth Avenue is a 618-foot (188-meter) residential skyscraper at 38th Street and Fifth Avenue in Midtown Manhattan, New York City. It was developed by RFR Davis and designed by Michael Graves. It has 55 floors and 197 units. The building uses air rights from two small adjoining buildings and a zoning bonus for providing a public plaza to maximize its floor area. As of July 2016, it is the 96th-tallest building in New York City. The building's site was originally home to a 5-story structure known as the Siebrecht Building which was home to Pierre Abraham Lorillard. Construction started in late 1999. The original architect of the project was Robert A. M. Stern, who was replaced by Michael Graves in 2001. The building topped-out in April 2002, and was opened that September.

452 Fifth Avenue (also the HSBC Tower and formerly the Republic National Bank Building) is an office building at the southwest corner of Fifth Avenue and 40th Street in the Midtown Manhattan neighborhood of New York City. The building includes the 30-story, 400-foot (120 m) HSBC Tower, completed in late 1985 and designed by Attia & Perkins. The 10-story Knox Building, a Beaux-Arts office building designed in 1902 by John H. Duncan, is preserved at the base of the skyscraper. 452 Fifth Avenue faces Bryant Park immediately to the north. The HSBC Tower is designed with a glass facade, which curves around the Knox Building to the north; a similar curved tower across Fifth Avenue was never built. The Knox Building's facade remains largely as it was originally designed, with decorated limestone cladding, a cornice above the sixth floor, and a mansard roof. The Knox Building is a New York City designated landmark and is on the National Register of Historic Places. Internally, the tower is tied into the stories of the Knox Building. The Knox Building was erected between 1901 and 1902 for Edward M. Knox, who operated the Knox Hat Company and leased out several stories to office tenants. In 1964, the Knox heirs sold the building to a group that founded the Republic National Bank of New York and used the building as the bank's headquarters. The bank acquired the neighboring lots in the 1970s and hired Attia & Perkins to design a tower to house its new world headquarters, which would wrap around the Knox Building. The tower was expanded in the 1990s and sold to the investment bank HSBC. In October 2009, HSBC Holdings sold the building to Midtown Equities and Israeli holding company IDB Group, the latter of which passed the building to a subsidiary, Property & Building Corporation (PBC). HSBC continued to lease back its space in the building until 2022, when the bank announced it would relocate.

275 Madison Avenue (also known as the Johns-Manville Building, American Home Products Building, and 22 East 40th Street) is a 43-story office building in the Murray Hill neighborhood of Manhattan in New York City. It is along the southeast corner of Madison Avenue and 40th Street, near Grand Central Terminal. The building, constructed from 1930 to 1931, was designed by Kenneth Franzheim in a mixture of the Art Deco and International styles. 275 Madison Avenue's three-story base is made of polished granite and contains large openings. On all the other floors, the facade contains vertical pilasters of white brick, as well as dark spandrels between windows, which were intended to give a vertical emphasis to the exterior. The 4th through 23rd floors contain several setbacks to comply with the 1916 Zoning Resolution. The building tapers to a rectangular cross-section on the 24th through 43rd floors. The interior of the base is designed with a main entrance lobby on 40th Street, as well as storefronts. Floor areas above the base range from 2,300 to 10,000 square feet (210 to 930 m2). 275 Madison Avenue was developed by Houston Properties, a firm headed by Texas entrepreneur Jesse H. Jones. It was originally known as 22 East 40th Street. The skyscraper opened at the onset of the Great Depression, and Houston Properties sold the skyscraper in 1933 to the New York Trust Company. In the mid-20th century, 275 Madison Avenue had several owners and was also known for major tenants Johns Manville and American Home Products. It has been owned by the RPW Group since 2016. The New York City Landmarks Preservation Commission designated 275 Madison Avenue as an official landmark in 2009.

Reuben's Restaurant and Delicatessen was a restaurant and Jewish deli in Manhattan, New York City founded by Arnold Reuben.

The Williams Club is in residence at the Penn Club of New York for alumni of Williams College. Until 2010, it had its own private clubhouse at 39th Street, which today operates as an unaffiliated boutique hotel.The Williams Club was founded in 1913 by Williams alumni in New York City as a place to socialize. The club was originally located at 291 Madison Avenue in a building donated by Mary Clark Thompson, wife of Williams alumnus Frederick Ferris Thompson. In 1921, it moved to 24 East 39th Street in Manhattan, which it then renovated in 1988. On June 1, 2010, however, the Williams Club ceased operating on its own and moved its membership program and related activities to the Princeton Club. After the permanent closure of the Princeton Club in fall 2021, the Williams Club moved to the Penn Club in March 2022. Today, members and their guests can use the Penn Club's facilities.

The New York Public Library (NYPL) is a public library system in New York City. With nearly 53 million items and 92 locations, the New York Public Library is the second largest public library in the United States (behind the Library of Congress) and the fourth largest in the world. It is a private, non-governmental, independently managed, nonprofit corporation operating with both private and public financing.The library has branches in the boroughs of the Bronx, Manhattan, and Staten Island and affiliations with academic and professional libraries in the New York metropolitan area. The city's other two boroughs, Brooklyn and Queens, are not served by the New York Public Library system, but rather by their respective borough library systems: the Brooklyn Public Library and the Queens Public Library. The branch libraries are open to the general public and consist of circulating libraries. The New York Public Library also has four research libraries, which are also open to the general public. The library, officially chartered as The New York Public Library, Astor, Lenox and Tilden Foundations, was developed in the 19th century, founded from an amalgamation of grass-roots libraries and social libraries of bibliophiles and the wealthy, aided by the philanthropy of the wealthiest Americans of their age. The "New York Public Library" name may also refer to its Main Branch, which is easily recognizable by its lion statues named Patience and Fortitude that sit either side of the entrance. The branch was declared a National Historic Landmark in 1965, listed on the National Register of Historic Places in 1966, and designated a New York City Landmark in 1967.

The Stephen A. Schwarzman Building, commonly known as the Main Branch or the New York Public Library, is the flagship building in the New York Public Library system in the Midtown Manhattan neighborhood of New York City. The branch, one of four research libraries in the library system, contains nine separate divisions. The structure contains four stories open to the public. The main entrance steps are at Fifth Avenue at its intersection with East 41st Street. As of 2015, the branch contains an estimated 2.5 million volumes in its stacks. The building was declared a National Historic Landmark, a National Register of Historic Places site, and a New York City designated landmark in the 1960s. The Main Branch was built after the New York Public Library was formed as a combination of two libraries in the late 1890s. The site, along Fifth Avenue between 40th and 42nd Streets, is located directly east of Bryant Park, on the site of the Croton Reservoir. The architectural firm Carrère and Hastings constructed the structure in the Beaux-Arts style, and the structure opened on May 23, 1911. The marble facade of the building contains ornate detailing, and the Fifth Avenue entrance is flanked by a pair of stone lions that serve as the library's icon. The interior of the building contains the Main Reading Room, a space measuring 78 by 297 feet (24 by 91 m) with a 52-foot-high (16 m) ceiling; a Public Catalog Room; and various reading rooms, offices, and art exhibitions. The Main Branch became popular after its opening, and saw 4 million annual visitors by the 1920s. It formerly contained a circulating library, though the circulating division of the Main Branch moved to the nearby Mid-Manhattan Library in 1970. Additional space for the library's stacks was constructed under adjacent Bryant Park in 1991, and the branch's Main Reading Room was restored in 1998. A major restoration from 2007 to 2011 was underwritten by a $100 million gift from philanthropist Stephen A. Schwarzman, for whom the branch was subsequently renamed. Since 2018, the branch has been undergoing an additional expansion. The Main Branch has been featured in many television shows and films.