Lefcourt Colonial Building

Library Hotel by Library Hotel Collection is a 60-room boutique hotel in New York City, located at 299 Madison Avenue (at 41st Street), near the New York Public Library Main Branch, Bryant Park, and Grand Central Terminal. The hotel was designed by architect Stephen B. Jacobs.Library Hotel by Library Hotel Collection boasts a unique organizing principle: each of its ten guest floors has a theme, designated after a major category of the Dewey Decimal Classification (the 5th floor, for example, is the 500s, the Sciences), with each room as a subcategory or genre, such as Mathematics (Room 500.001) or Botany (Room 500.004). (Dewey categories 000, 100, and 200 are placed on the 10th, 11th, and 12th floors, respectively.) Other room themes include Erotic Literature (Room 800.001), Poetry (Room 800.003), and Music (Room 700.005). All rooms have a small complement of 50–100 books and decorations that accompany the theme, with 6,000 books overall throughout the hotel.Because of this classification scheme, the hotel owners were sued in 2003 by the OCLC (owners of the Dewey Decimal Classification system). OCLC reached an agreement with the hotel enabling the hotel to continue using the Dewey system.The Library Hotel is owned and operated by Henry Kallan, whose Library Hotel Collection includes Manhattan's Casablanca Hotel, Hotel Giraffe and Hotel Elysee.

Hills Learning is an Asian language school in New York City. It is located near Grand Central Terminal and has been recognized by several television stations, websites, and publications, such as PBS, TBS, CBS New York, and Chopsticks NY.

One Grand Central Place, originally the Lincoln Building, is a 53-story, 673 feet (205 m) tall neo-Gothic office building at 60 East 42nd Street in Midtown Manhattan, New York City. It is bounded by Madison Avenue to the west, East 41st Street to the south, and Park Avenue to the east. One Grand Central Place is near other skyscrapers such as the Chrysler Building, MetLife Building, and One Vanderbilt. It has direct in-building access to Grand Central Terminal to the north. As of 2021, it is the 91st-tallest building in the city, tied with the 277 Fifth Avenue, Barclay Tower, and One Court Square. The building is assigned its own ZIP Code, 10165; it was one of 41 buildings in Manhattan that had their own ZIP Codes as of 2019.

275 Madison Avenue (also known as the Johns-Manville Building, American Home Products Building, and 22 East 40th Street) is a 43-story office building in the Murray Hill neighborhood of Manhattan in New York City. It is along the southeast corner of Madison Avenue and 40th Street, near Grand Central Terminal. The building, constructed from 1930 to 1931, was designed by Kenneth Franzheim in a mixture of the Art Deco and International styles. 275 Madison Avenue's three-story base is made of polished granite and contains large openings. On all the other floors, the facade contains vertical pilasters of white brick, as well as dark spandrels between windows, which were intended to give a vertical emphasis to the exterior. The 4th through 23rd floors contain several setbacks to comply with the 1916 Zoning Resolution. The building tapers to a rectangular cross-section on the 24th through 43rd floors. The interior of the base is designed with a main entrance lobby on 40th Street, as well as storefronts. Floor areas above the base range from 2,300 to 10,000 square feet (210 to 930 m2). 275 Madison Avenue was developed by Houston Properties, a firm headed by Texas entrepreneur Jesse H. Jones. It was originally known as 22 East 40th Street. The skyscraper opened at the onset of the Great Depression, and Houston Properties sold the skyscraper in 1933 to the New York Trust Company. In the mid-20th century, 275 Madison Avenue had several owners and was also known for major tenants Johns Manville and American Home Products. It has been owned by the RPW Group since 2016. The New York City Landmarks Preservation Commission designated 275 Madison Avenue as an official landmark in 2009.

The Belmont Hotel was an early 20th-century skyscraper-like hotel at Park Avenue and 42nd Street in Midtown Manhattan, New York City. The Belmont Hotel was built between 1904 and 1908. At 308 feet (94 m), it was the tallest hotel in the world when built and was demolished in 1939. The 42nd Street Airlines Terminal was built in its place.

The Church of the Holy Trinity is an Episcopal parish church located at 316 East 88th Street between First and Second Avenues in the Yorkville neighborhood of Manhattan, New York City.

Grand Central Madison is a commuter rail terminal for the Long Island Rail Road (LIRR) currently under construction in the Midtown East neighborhood of Manhattan in New York City, being built as part of the East Side Access project. The new terminal, sometimes referred to as the LIRR's East Side station, started construction in 2008 and is planned to open in December 2022. It is located beneath Grand Central Terminal, which serves the MTA's Metro-North Railroad.The Long Island Rail Road has terminated on the west side of Manhattan, at Penn Station and its predecessor, since 1910. The new terminal aims to ease congestion at Penn Station and decrease travel times for passengers going to and from the east side of Manhattan. The new terminal will provide transfers to the Metro-North Railroad's Harlem, Hudson, and New Haven Lines, as well as the New York City Subway at Grand Central–42nd Street station.

The Williams Club is in residence at the Penn Club of New York for alumni of Williams College. Until 2010, it had its own private clubhouse at 39th Street, which today operates as an unaffiliated boutique hotel.The Williams Club was founded in 1913 by Williams alumni in New York City as a place to socialize. The club was originally located at 291 Madison Avenue in a building donated by Mary Clark Thompson, wife of Williams alumnus Frederick Ferris Thompson. In 1921, it moved to 24 East 39th Street in Manhattan, which it then renovated in 1988. On June 1, 2010, however, the Williams Club ceased operating on its own and moved its membership program and related activities to the Princeton Club. After the permanent closure of the Princeton Club in fall 2021, the Williams Club moved to the Penn Club in March 2022. Today, members and their guests can use the Penn Club's facilities.

The 42nd Street Airlines Terminal, on the southwest corner of Park Avenue and 42nd Street in Midtown Manhattan, was the first of three airline terminals constructed in New York City. It was located at the site of the former Hotel Belmont. During this period of aviation, reservations, ticketing and baggage handling took place at this facility for the airlines American, Eastern, TWA, United and Pan Am. Passengers would be transferred by bus to Newark Airport, and later to the New York International Airport. The changing economics and increasing popularity of air travel eventually led to the creation of new air terminals: the East Side Airline Terminal near the Queens Midtown Tunnel and the West Side Airline Terminal near the Lincoln Tunnel. In 1954 this facility, which had become restricted to ticketing only, was renamed the Airlines Building. The declining importance of the facility led to its demolition in 1978, to become the site of the Philip Morris Building at 120 Park Avenue.

Hotel Manhattan (also known as Manhattan Hotel) was a "railroad hotel" on the northwest corner of Madison Avenue and 42nd Street in Manhattan, New York City, New York.

101 Park Avenue is a 629-foot (192 m) tall skyscraper at 41st Street and Park Avenue in the Murray Hill neighborhood of Manhattan, New York City, New York. It was completed in 1979 to 1982 and has 49 floors. Eli Attia Architects designed the tower. The building contains the Museum of the Dog. The building is assigned its own ZIP Code, 10178; it was one of 41 buildings in Manhattan that had their own ZIP Codes as of 2019.

Le Pavillon is a restaurant in Midtown Manhattan, New York City. The restaurant is owned by the Dinex Group, a restaurant company led by chef and restaurateur Daniel Boulud. Le Pavillon opened in May 2021 in One Vanderbilt, a skyscraper completed in 2020 in Midtown East.