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Julia Vargas Avenue is a central east–west arterial road that passes through Ortigas Center in Metro Manila, Philippines. It is a four-lane divided road with one-way protected bike lanes that runs parallel to Ortigas Avenue to the north and Shaw Boulevard to the south. The avenue stretches 2.3 kilometers (1.4 mi) from Eulogio Rodriguez Jr. Avenue (C-5 Road) in Ugong, Pasig in the east to Epifanio de los Santos Avenue (EDSA) in Wack-Wack Greenhills, Mandaluyong in the west. It was named for philanthropist Doña Julia Vargas y Camus vda. de Ortigas, wife of Ortigas & Company Limited Partnership founder Don Francisco Ortigas y Barcinas who owned the Hacienda de Mandaloyon estate on which Ortigas Center was built.

UnionBank Plaza is an office skyscraper located in Pasig, Philippines. It rises 206 metres (676 feet) from ground level to roof, and is currently the tallest complete building in Pasig, and the 14th-tallest building in the country and Metro Manila as well. The building has 49 levels above ground, and 6 basement levels.True to its name, the bank serves as the headquarters for Union Bank of the Philippines, the seventh-largest bank in the Philippines in terms of assets. Other tenants of UnionBank Plaza include major business process outsourcing companies, like Sykes Enterprises, Branders.com, PCCW, among others. However, the building's main tenant, UnionBank, also maintains some executive offices at the SSS Building in Makati.

Marco Polo Ortigas Manila (Chinese: 马尼拉奥迪加斯马哥孛罗酒店; pinyin: Mǎnílā Àodíjiāsī Mǎgē Bèiluō Jiǔdiàn) is a hotel at the Ortigas Center in Pasig, Metro Manila, Philippines.

One Corporate Centre is an office skyscraper in Pasig, Metro Manila, Philippines. It is the 13th-tallest building in the country and Metro Manila as well with a height of 202 metres (662.73 feet) from ground to tip of architectural antenna. The building has 45 floors above ground including 7 floors for commercial purposes, and 9 basement levels for parking.One Corporate Centre was designed by Philip H. Recto Architects, and is developed and owned by Amberland Corporation.

The John F. Cotton Corporate Wellness Center or John F. Cotton Hospital Center for Corporation Wellness, formerly known only as the John F. Cotton Hospital (JFCH), is a privately owned hospital located inside the compound of Meralco, a major electric company in the Philippines.Being a private facility, it is situated inside the Meralco Center at Ortigas Avenue in Pasig. The transformation of the JFCH into an integrated corporate wellness center made the Manila Electric Company the first corporation in the Philippines to institutionalize the implementation of such a program.

St. Paul College, Pasig, also referred to as SPCP or SPC Pasig, is a private, Roman Catholic school exclusively for girls in Pasig, Philippines run by the Congregation of Sisters of Saint Paul of Chartres, a teaching order founded as the Daughters of the School. St. Paul College, Pasig, is located in St. Paul Road, Brgy. Ugong, Pasig, Philippines. It was established in 1970 when Saint Paul University Manila (then St. Paul College, Manila) decided to relocate their kindergarten, grade school and high school departments to a different area.

The Medical City Ortigas is a tertiary care hospital in Pasig, Metro Manila, Philippines. It is the main hospital of The Medical City (TMC) which maintains a network of hospitals and clinics which are mostly based in the Philippines.

Taipan Place is a 22-storey office building in Ortigas Center, Pasig.

The Benpres Building (Tagalog: Gusaling Benpres), originally known as the Chronicle Building, was a six-story Filipino modernist heritage building built in 1969 and inaugurated in 1971, located in Ortigas Center, Pasig.The building was designed by architect Gabriel Formoso and built in 1969 to serve as the new headquarters of the Manila Chronicle. The newspaper formally transferred to the building in February 1971 and the building was formally dedicated on April 2, 1971. However, President Ferdinand Marcos' declaration of Martial Law less than two years later saw the closure of the Chronicle, and the newspaper did not return to the building even after Marcos was deposed. After the People Power Revolution of 1986, the building was returned to the Lopez family and was renamed the Benpres Building after Eugenio Lopez, Sr.'s parents—former Iloilo governor Benito López, and Presentación Hofileña López.In 2016, the Lopez group of companies announced its intentions to redevelop the property on which the Benpres building stood, with two buildings planned to rise on the property. The building was demolished in 2019.

Wynsum Corporate Plaza is a 35-storey office skyscraper in Ortigas Center, in Pasig City. The building is equipped with a double glazed curtain wall system for additional energy and efficient cooling complemented by a combination of a polished red granite exterior wall and composite cladding. It also has 11 elevators.

Meralco Avenue is a north-south thoroughfare located in Ortigas Center in Pasig, Metro Manila, Philippines. It links Ortigas Avenue in the north and Shaw Boulevard in the south and borders the western edge of Valle Verde in Ugong. It is named for the Manila Electric Company, also known as Meralco, which is headquartered on the avenue's junction with Ortigas Avenue. Other notable businesses on Meralco Avenue include UnionBank Plaza, Marco Polo Ortigas Manila, Ayala Malls The 30th, Metrowalk, and the mixed-use development called Capitol Commons at the former Rizal Provincial Capitol lot on Meralco and Shaw Boulevard.

The López Museum and Library, also known as simply the Lopez Museum, is a Philippine art and history museum and library located in Pasig, Philippines at the ground floor of the Benpres Building, Exchange Road corner Meralco Avenue, Ortigas Center.