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UnionBank Plaza is an office skyscraper located in Pasig, Philippines. It rises 206 metres (676 feet) from ground level to roof, and is currently the tallest complete building in Pasig, and the 14th-tallest building in the country and Metro Manila as well. The building has 49 levels above ground, and 6 basement levels.True to its name, the bank serves as the headquarters for Union Bank of the Philippines, the seventh-largest bank in the Philippines in terms of assets. Other tenants of UnionBank Plaza include major business process outsourcing companies, like Sykes Enterprises, Branders.com, PCCW, among others. However, the building's main tenant, UnionBank, also maintains some executive offices at the SSS Building in Makati.

Marco Polo Ortigas Manila (Chinese: 马尼拉奥迪加斯马哥孛罗酒店; pinyin: Mǎnílā Àodíjiāsī Mǎgē Bèiluō Jiǔdiàn) is a hotel at the Ortigas Center in Pasig, Metro Manila, Philippines.

The John F. Cotton Corporate Wellness Center or John F. Cotton Hospital Center for Corporation Wellness, formerly known only as the John F. Cotton Hospital (JFCH), is a privately owned hospital located inside the compound of Meralco, a major electric company in the Philippines.Being a private facility, it is situated inside the Meralco Center at Ortigas Avenue in Pasig. The transformation of the JFCH into an integrated corporate wellness center made the Manila Electric Company the first corporation in the Philippines to institutionalize the implementation of such a program.

O Bar is an LGBT-friendly bar and drag venue in Metro Manila. Tatler Asia has ranked O Bar among the top safe queer spaces in the Philippines.

Meralco Theater is a theater located at the compound of Meralco, Ortigas Avenue in Pasig, Philippines. It used to be known as the Meralco Auditorium. It seats over 1,500 people and is a popular venue for various concerts, plays, musicals and events. Meralco Theater had completed it's interior renovation. Rumors and heavy speculations from news sources said that the Philippines longest running noontime variety show, Eat Bulaga! will move to the theater soon.

Taipan Place is a 22-storey office building in Ortigas Center, Pasig.

Wynsum Corporate Plaza is a 35-storey office skyscraper in Ortigas Center, in Pasig City. The building is equipped with a double glazed curtain wall system for additional energy and efficient cooling complemented by a combination of a polished red granite exterior wall and composite cladding. It also has 11 elevators.

One Corporate Centre is an office skyscraper in Pasig, Metro Manila, Philippines. It is the 13th-tallest building in the country and Metro Manila as well with a height of 202 metres (662.73 feet) from ground to tip of architectural antenna. The building has 45 floors above ground including 7 floors for commercial purposes, and 9 basement levels for parking.One Corporate Centre was designed by Philip H. Recto Architects, and is developed and owned by Amberland Corporation.

Robinsons Cyberscape is an office development located in Ortigas Center, Quezon City, Metro Manila, one of the oldest CBDs in the Philippines. Owned by Robinson Land Corporation, the development is composed of two buildings named Robinsons Cyberscape Alpha (Tower One) and Robinsons Cyberscape Beta (Tower Two). Expected to be fully turned over by 2016, these buildings introduce a total of 80,000 m2 (861,112.83 sq ft) square meters of additional space in Ortigas CBD.

The Orient Square (officially The Orient Square Building or Orient Square IT Center, acronym: OSB or use as a code: OS) is a first-class, high-rise and tallest building along Ortigas Center's main road, F. Ortigas Jr. Avenue (known as Emerald Avenue) in Pasig, Philippines. It rises 160 metres from ground level to roof, and is currently the 7th tallest complete building in Pasig, and the 76th tallest building in the Philippines. The building has 38 levels above ground, and 7 basement levels. It will be a mixed-use building, both office and residential. Orient Square Building is currently one of the modern landmarks in Ortigas Center because of its architectural design and its one-of-a-kind curtain wall that glitters at night from the lights inside the building because of its transparency. The Philippine Economic Zone Authority (PEZA) declared it an Information Technology Building in January 2006. The building has a 6-level concrete podium as its base, while its main body is fully clad with aluminium unitized curtain wall. It has a distinctive design of having multiple corners, especially on the top floors, making it easily recognizable among the buildings in Ortigas Center.

Julia Vargas Avenue is a central east–west arterial road that passes through Ortigas Center in Metro Manila, Philippines. It is a four-lane divided road with one-way protected bike lanes that runs parallel to Ortigas Avenue to the north and Shaw Boulevard to the south. The avenue stretches 2.3 kilometers (1.4 mi) from Eulogio Rodriguez Jr. Avenue (C-5 Road) in Ugong, Pasig in the east to Epifanio de los Santos Avenue (EDSA) in Wack-Wack Greenhills, Mandaluyong in the west. It was named for philanthropist Doña Julia Vargas y Camus vda. de Ortigas, wife of Ortigas & Company Limited Partnership founder Don Francisco Ortigas y Barcinas who owned the Hacienda de Mandaloyon estate on which Ortigas Center was built.

The One Galleon Place is a planned skyscraper that will rise in Pasig, Philippines. The building will be the flagship project of developer Ortigas & Co. Ltd. Partnership (OCLP), one of the oldest real estate developers in the Philippines. It will be a mixed use building, the upper half will accommodate a 5-star luxury hotel, and the lower half will be for office units. In commemoration of OCLP's 75th anniversary in 2009, it is projected to be 75 storeys and at least 400 metres high.