John F. Cotton Corporate Wellness Center

Marco Polo Ortigas Manila (Chinese: 马尼拉奥迪加斯马哥孛罗酒店; pinyin: Mǎnílā Àodíjiāsī Mǎgē Bèiluō Jiǔdiàn) is a hotel at the Ortigas Center in Pasig, Metro Manila, Philippines.

UnionBank Plaza is an office skyscraper located in Pasig, Philippines. It rises 206 metres (676 feet) from ground level to roof, and is currently the tallest complete building in Pasig, and the 14th-tallest building in the country and Metro Manila as well. The building has 49 levels above ground, and 6 basement levels.True to its name, the bank serves as the headquarters for Union Bank of the Philippines, the seventh-largest bank in the Philippines in terms of assets. Other tenants of UnionBank Plaza include major business process outsourcing companies, like Sykes Enterprises, Branders.com, PCCW, among others. However, the building's main tenant, UnionBank, also maintains some executive offices at the SSS Building in Makati.

Robinsons Cyberscape is an office development located in Ortigas Center, Quezon City, Metro Manila, one of the oldest CBDs in the Philippines. Owned by Robinson Land Corporation, the development is composed of two buildings named Robinsons Cyberscape Alpha (Tower One) and Robinsons Cyberscape Beta (Tower Two). Expected to be fully turned over by 2016, these buildings introduce a total of 80,000 m2 (861,112.83 sq ft) square meters of additional space in Ortigas CBD.

Crowne Plaza Manila Galleria is hotel located at the Ortigas business district in Manila, Philippines. Built in 2004, Crowne Plaza Manila is the first Crowne Plaza property in Manila. The hotel has 263 deluxe and suite rooms. The current General Manager of the hotel as of 2019 is Jolly Barun.Crowne Plaza was the first hotel in the Philippines to roll out a mobile Internet solution for its Wi-Fi needs.In 2011, Crowne Plaza has undertaken a refurbishment of its ballrooms. The renovation of events space marks the facility's first make-over since it opened its doors in 2005.In 2018, the bicameral conference committee for the Bangsamoro Organic Law was held in the hotel.In 2019, the Philippine Fashion Week was held in the hotel, with it becoming its permanent home for the next three years.

O Bar is an LGBT-friendly bar and drag venue in Metro Manila. Tatler Asia has ranked O Bar among the top safe queer spaces in the Philippines.

The Medical City Ortigas is a tertiary care hospital in Pasig, Metro Manila, Philippines. It is the main hospital of The Medical City (TMC) which maintains a network of hospitals and clinics which are mostly based in the Philippines.

The Robinsons Equitable Tower, formerly known as the Robinsons PCI Bank Tower, is an office skyscraper located in Pasig, Philippines. It was completed in 1997 and stands at 175 metres (574 feet), making it the current 2nd-tallest complete building in Pasig, and is one of the highest building in the Philippines.

Wynsum Corporate Plaza is a 35-storey office skyscraper in Ortigas Center, in Pasig City. The building is equipped with a double glazed curtain wall system for additional energy and efficient cooling complemented by a combination of a polished red granite exterior wall and composite cladding. It also has 11 elevators.

Asian Development Bank Avenue, commonly referred to as simply ADB Avenue, is a short north–south thoroughfare in Ortigas Center, eastern Metro Manila, Philippines. It is an eight-lane divided road connecting Ortigas Avenue in the north to Julia Vargas Avenue in the south. It was formerly part of San Miguel Avenue, named after food and beverage giant San Miguel Corporation that is headquartered on the junction with Julia Vargas. This section of San Miguel Ave. from Julia Vargas to Ortigas Ave. was renamed in 1991 after the Asian Development Bank moved from its old building on Roxas Boulevard (now occupied by the Department of Foreign Affairs) to its present 6.5-hectare headquarters on the avenue's junction with Guadix Drive.ADB Avenue and San Miguel Avenue form the eastern city limit of Mandaluyong and the western city limit of Pasig. North of Guadix Drive, the road enters Ugong Norte, Quezon City. It is also home to the Robinsons Galleria and The Podium shopping complexes.

Robinsons Galleria, also known as Robinsons Galleria Ortigas, is a mixed-use complex and shopping mall located at EDSA corner Ortigas Avenue, Quezon City just near SM Megamall. The mall is owned by Robinsons Malls, and it is their flagship mall. It is the 1st Robinsons Mall to bear the Galleria branding. It was built on January 12, 1990 with a total gross floor area of approximately 216,000 m2 (2,330,000 sq ft).

Taipan Place is a 22-storey office building in Ortigas Center, Pasig.

The Orient Square (officially The Orient Square Building or Orient Square IT Center, acronym: OSB or use as a code: OS) is a first-class, high-rise and tallest building along Ortigas Center's main road, F. Ortigas Jr. Avenue (known as Emerald Avenue) in Pasig, Philippines. It rises 160 metres from ground level to roof, and is currently the 7th tallest complete building in Pasig, and the 76th tallest building in the Philippines. The building has 38 levels above ground, and 7 basement levels. It will be a mixed-use building, both office and residential. Orient Square Building is currently one of the modern landmarks in Ortigas Center because of its architectural design and its one-of-a-kind curtain wall that glitters at night from the lights inside the building because of its transparency. The Philippine Economic Zone Authority (PEZA) declared it an Information Technology Building in January 2006. The building has a 6-level concrete podium as its base, while its main body is fully clad with aluminium unitized curtain wall. It has a distinctive design of having multiple corners, especially on the top floors, making it easily recognizable among the buildings in Ortigas Center.