Wesley Union African Methodist Episcopal Zion Church

Camp Curtin is a historic neighborhood in Harrisburg, Pennsylvania's northern end, located in Uptown and named for the American Civil War camp of the same name. It is bordered currently by landmarks of Fifth Street to the west, the railroad tracks next to the Pennsylvania Farm Show Complex to the east, Maclay Street to the south, and Reels Lane to the North.

The Camp Curtin Fire Station is a historic fire station located at Harrisburg, Dauphin County, Pennsylvania and named for the Civil War camp of the same name. It was added to the National Register of Historic Places in 1981, and was decommissioned the year prior because it was no longer large enough to accommodate standard fire trucks.

William Donaldson House is a historic home located at Harrisburg, Dauphin County, Pennsylvania. It was designed by Smith & Warner and built in 1887, and is a 3+1⁄2-story Queen Anne style dwelling funded by William Mayne Donaldson, president of the Donaldson Paper Company. A rear addition was constructed about 1910. It has a stone foundation, brick first story, and wood shingle second and third stories. It features irregular massing, a variety of surface textures, multiple intersecting roofs, bay windows, porch and balconies, and a turret with spindle. The house was converted to apartments in 1925.It was added to the National Register of Historic Places in 1990.

Sheffield Apartments is a historic apartment building located at Harrisburg, Dauphin County, Pennsylvania. It was built in 1925, and is a three-story, rectangular brick building in the Mission Revival style. The facade is three bays wide, and it features three story bay windows on each side of the center entrance bay. It has 14 apartments.It was added to the National Register of Historic Places in 1990.

Uptown is a section of Harrisburg, Pennsylvania located North of the Midtown and Downtown neighborhoods. Bordered by the Susquehanna River to the West, Maclay Street to the South, North 7th Street to the East and Susquehanna Township to the North, the neighborhood is home to many ornate mansions along Front Street and Italian Lake, as well as moderately sized homes exemplifying character of early 20th-century architecture. After being devastated in 1972 by the flooding of Hurricane Agnes, the neighborhood slipped into a moderate decline. Since then, new homeowners have made improvements, causing property values to increase dramatically through the beginning of the 21st century. With the Susquehanna River's Riverfront Park and Capital Area Greenbelt within walking distance—as well as Italian Lake—Uptown Harrisburg is an example of relaxed urban living. Much of Uptown's development (post-automobile) lends itself to having longer blocks, rear alleys with detached garages, and shopping plazas/large surface parking lots.Uptown contains three Historic Places on the National Register: Camp Curtin Fire Station, Camp Curtin Memorial Methodist Episcopal Church, and Polyclinic Medical Center.

The Pennsylvania National Fire Museum is a museum devoted to fire fighter heritage in Harrisburg, Pennsylvania, United States. The museum has an outstanding collection of artifacts from the hand-drawn equipment, extensive collection of vintage fire apparatus, artifacts, pictures and information about the history of fire fighting in Pennsylvania and throughout the United States.The museum is housed in the former 1899 Victorian firehouse Reily Hose Company No. 10, of the Harrisburg Bureau of Fire.

Kesher Israel Congregation is an Orthodox synagogue in the Uptown neighborhood of Harrisburg, Pennsylvania, United States. Founded in 1902, it is officially affiliated with the Orthodox Union.

Simon Cameron School is a historic school building located at Harrisburg, Dauphin County, Pennsylvania. It was built in 1896, and is a two-story, brick and frame building, with a hip roof covered in slate shingles. It sits on a brownstone foundation. It is 12 bays wide and 8 bays deep, with an 8 bay wide, 6 bay deep rear section added in 1900. It is named for Pennsylvania politician Simon Cameron (1799–1889).It was added to the National Register of Historic Places in 1986.

Polyclinic Medical Center, also known as Polyclinic Hospital, is a polyclinic in Harrisburg, Pennsylvania, and part of UPMC Pinnacle, a regional system of the University of Pittsburgh Medical Center (UPMC) that serves South Central Pennsylvania. Originally opening in 1909. Most of the building is occupied by Pennsylvania Psychiatric Institute. On other floors are other programs, including two addiction clinics, physical and occupational therapy, audiology and hearing center, HIV clinic, outpatient laboratory, primary care office, and surgery optimization. The original building housing the first hospital at this location, dates to 1925–1926, with expansions in 1949–1952, 1955, 1959, and 1960. Its architecture is that of the Colonial Revival period. It was listed on the National Register of Historic Places in 2004.

Capitol Heights is a community of nearly 200 townhouse and single-family duplexes in the Midtown neighborhood of Harrisburg, Pennsylvania. Most of the new homes are located east of Third between Kelker and Reily and along Fulton, 4th and 5th street. The neighborhood is known for its generic suburban-style architecture fitted to the existing street grid. The area was previously referred to informally as "Lottsville" due to its many abandoned and vacant lots, so the City and private developers worked together in the 2000s as it was a targeted area for demolition and urban renewal.

Temple Ohev Sholom, established in 1853, is the oldest Jewish synagogue in Harrisburg, Pennsylvania, United States and its surrounding area. It was established as an Orthodox congregation. In 1867, it became a Reform congregation.

The Old Uptown Historic District is a historic district in the Midtown neighborhood of Harrisburg, Pennsylvania. The district stretches from Reily to Maclay between Second and Third street. It consists of large Queen Anne and Italianate architecture built in the late 19th century and very early 20th century. The northern part of the historic district is currently being aggressively renovated by real estate investors.