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Columbia International University (CIU) founded in 1923, is a private Christian university in Columbia, South Carolina.

Eau Claire is a community in Columbia, South Carolina.

The Midlands region of South Carolina is the middle area of the state. The region's main center is Columbia, the state's capital. The Midlands is so named because it is halfway point between the Upstate and the Lowcountry. The main area code is 803. The area has become a major business center in the state, for its growing production of paper products, textile, medical supplies and steel. It is also a center for farming and medical care. The area is also involved in attractions and tourism, featuring shopping, fishing and amusement. As of the 2020 census the Midlands population was 1,019,439.

Camille Griffin Graham Correctional Institution is a South Carolina Department of Corrections (SCDC) state prison for women in Columbia, South Carolina. The Women's Reception and Evaluation Center, which processes all females entering SCDC, is in the prison.The prison opened in 1973, as "Women's Correctional Institution". It was renamed in 2002 in honor of the first female warden of a maximum-security male prison in South Carolina, Camille Griffin Graham. In October 2019, health care staff at the prison reported that women who reported mental health symptoms were punished with nutraloaf and were denied hygiene items. The warden, Marian Boulware, resigned in January 2020 after the reports. The prison houses the State of South Carolina death row for women.In January 2011, a young female prisoner with a history of mental illness succeeded in committing suicide. The death is under investigation. In February 2019, another prisoner killed herself. In 2012, an inmate went into labor and was not aided by staff. One of her twins was delivered into a toilet where he died. The state reached a settlement for over a million dollars seven years later.The prison is one of 40, and the only prison in South Carolina, participating in Girl Scouts of the USA Beyond Bars program, allowing Girl Scouts visitation/bonding with their incarcerated mothers.

The Broad River Correctional Institution (BRCI) is a South Carolina Department of Corrections state prison for men located in Columbia, South Carolina. South Carolina's execution chamber is located in Broad River. The adjacent Kirkland Correctional Institution lies just to its south side. The prison opened in 1988. In January 1990, death row inmates were moved from the Central Correctional Institution to Broad River. In 1990, executions began at BRCI. On April 12, 1997, death row inmates were moved to the Lieber Correctional Institution. In September 2017, death row inmates were moved to Kirkland Correctional Institution. On July 11, 2019, death row inmates were moved from Kirkland Correctional Institution to the housing unit that was originally built for them at Broad River.

Kirkland Correctional Institution is a state prison for men located in Columbia, Richland County, South Carolina, United States, owned and operated by the South Carolina Department of Corrections.Kirkland has a special role in South Carolina's prison system as the point of intake and assessment for all male state prisoners, the site of the state's Maximum Security Unit, and a health care facility. The prison was first opened in 1975, and houses a maximum of 1707 inmates, plus another 50 in the Max unit and 24 in the infirmary. In September 2017, death row inmates were moved to Kirkland Correctional Institution. It is the prison in which Alex Murdaugh is serving his life sentence. The state's Broad River Correctional Institution is adjacent to the north.

Columbia High School a public high school in the St. Andrews area of Columbia, South Carolina, United States. Columbia High School was originally housed in the former Columbia Female Academy (established 1816) at 1323 Washington Street at the corner with Marion Street. This building was leased to the Richland County Commissioners of Schools in 1884. The school became Columbia's first public high school in 1895 as the Washington Street School. The original Columbia High School building was constructed in 1915 on that site. The current building was constructed in 1975.

WMFX (102.3 MHz) is a commercial FM radio station licensed to St. Andrews, South Carolina, and serving the Columbia metropolitan area. The Alpha Media outlet broadcasts a classic rock radio format, with a few alternative rock artists also in the playlist. The station goes by the name Fox 102.3 and its current slogan is "Columbia's Rock Station." Its radio studios and offices are located on Pineview Drive in Columbia. WMFX has an effective radiated power (ERP) of 6,000 watts. Its transmitter is on Winterwood Road near Monticello Road.

St. Andrews is a census-designated place (CDP) in Richland County, South Carolina, United States. The population was 20,493 at the 2010 census. It is part of the Columbia, South Carolina Metropolitan Statistical Area.

WBAJ (890 kHz) is an AM radio station licensed to Blythewood, South Carolina, and serving the Columbia metropolitan area. WBAJ carries a Christian radio format and is owned by Bible Clarity, a Seventh-day Adventist organization. WBAJ is a daytimer station. By day it is powered at 50,000 watts, using a non-directional antenna. But because AM 890 is a clear channel frequency reserved for Class A WLS Chicago, WBAJ must sign off at night to avoid interference. During critical hours, WBAJ is powered at 8,500 watts. Programming is also heard on 85 watt FM translator 105.9 W290CY in Columbia.

Dutch Square is an enclosed shopping mall located in the city of Columbia, South Carolina. Currently, it features more than forty stores and restaurants, as well an AMC movie theater. Its anchor stores are Burlington Coat Factory and Office Depot.

Lutheran Theological Southern Seminary (LTSS) is a theological seminary of the Evangelical Lutheran Church in America (ELCA) and located in Columbia, South Carolina. It offers theological degrees. In 2012, it merged with Lenoir-Rhyne University, also affiliated with the ELCA. Although Lenoir-Rhyne is based in Hickory, North Carolina, LTSS operates as a satellite campus in Columbia.