Virginia Tech Carilion School of Medicine and Research Institute

Mountain View, also known as the Fishburn Mansion, is a historic home in the Mountain View neighborhood in Roanoke, Virginia. It is a 2+1⁄2-story, rectangular Georgian Revival-style house that was built in 1907. It features a colossal portico consisting of two clusters of three fluted Ionic order columns supporting an Ionic entablature topped by a pediment containing a lunette. It also has a series of one-story porches, a conservatory, and a porte cochere.It was listed on the National Register of Historic Places in 1980.

Mountain View is a Roanoke, Virginia neighborhood located in central Roanoke north of the Roanoke River. It borders the neighborhoods of Norwich on the west, West End on the east, Hurt Park on the north and Raleigh Court and Wasena on the south.In March 2011, This Old House, America’s most respected home improvement authority, selected Mountain View as Virginia’s “Best Old House Neighborhood 2011” in its annual list of “North America’s most timeless neighborhoods—places where lovingly crafted old houses have extraordinary pasts and unarguably promising futures.”Mountain View was one of 64 neighborhoods in the U.S. and Canada recognized by This Old House, which distributed nomination forms to more than 14,000 historical societies, neighborhood groups, and preservation nonprofits to compile its “biggest-ever list of off-the-beaten-path places that are worth eyeing for a great old home.”

The Roanoke City Health Center is a historic health care facility at 515 8th Street SW in Roanoke, Virginia. It is a modest single-story brick building in a U-shaped plan. It was built in 1951, and exemplifies trends of the period in the provision of health care to rural communities. It also exhibits features distinctive to the Jim Crow era of segregated facilities, as it was originally designed with separate areas for whites and African Americans.The building, now vacant, was listed on the National Register of Historic Places in 2016.

Southwest Historic District is a national historic district located at Roanoke, Virginia. It encompasses 1,547 contributing buildings constructed between 1882 and 1930 in the Roanoke neighborhoods of Old Southwest, Mountain View, and Hurt Park. It is a primarily residential district with houses in a variety of popular late-19th and early-20th century architectural styles. The district also includes a small number of commercial structures, churches, and two schools.It was listed on the National Register of Historic Places in 1985.

Wasena is a Roanoke, Virginia (United States) neighborhood located in south, central Roanoke bisected by U.S. Route 221 (Main Street), immediately to the south of the Roanoke River. It borders the neighborhoods of Raleigh Court on the west, Old Southwest on the north and east and Mountain View via the Wasena Bridge across the Roanoke River on the north, and Franklin-Colonial on the south. As of the 2000 U.S. Census, Wasena has a population of 1,633 residents.

The Salvation Army Citadel is a historic religious building in Roanoke, Virginia. Built in 1941 in the Colonial Revival style, the site was the headquarters for the Salvation Army's operations in Roanoke, including church services, social services, and outreach. After the church constructed a new primary location in 1980, the building served as the Red Shield Lodge, a men's homeless shelter, until closing in 2018. It was listed to the National Register of Historic Places in 2020, and reopened that year as an apartment building.

Wasena Historic District is a national historic district located in the Wasena neighborhood of Roanoke, Virginia. It encompasses 574 contributing buildings, 1 contributing site, 3 contributing structures, and 3 contributing objects. It is a primarily residential district with single-family dwellings. Also in the district are a few commercial buildings, several industrial buildings, a park along the river and the Wasena Bridge.

The Memorial Bridge is a two-lane, 785-foot-long (239 m) bridge spanning the Roanoke River along U.S. Route 11 (Memorial Avenue) in Roanoke, Virginia. The bridge serves as a connection between the southwestern areas of the city (including the Grandin Village area) with central Roanoke. Built by contractor W.W. Boxley, the bridge consists of five 120 feet (37 m) spans, with construction commencing in summer 1925. The bridge officially opened to traffic on May 6, 1926, at a final cost of $282,750.Although officially open to traffic for over four months, its official dedication occurred on August 30 with U.S. Representative Clifton Woodrum in attendance. The delay in its dedication was attributed to delays involving the creation of the bronze, dedication plaques. It is officially dedicated to Roanoke's veterans of World War I.The bridge features five plaques, with their contents determined by the Roanoke City Council. Four of them feature quotations from notable historic figures: Patrick Henry, Theodore Roosevelt, Stonewall Jackson and Thomas Jefferson; with the fifth containing the names of all the soldiers from Roanoke who died in World War I. Although dedicated to the veterans who fought in World War I, many did not attend the dedication ceremony due to its not being originally conceived as a monument to former servicemen. The bridge was officially rededicated on November 11, 1991, sixty-five years after its original dedication.Due to its deteriorating state as a result of corrosion from salt used for deicing in the winter, in April 2002 a major restoration of the span commenced. Costing $1.17 million and completed by spring 2003, the restoration included the replacement of corroded elements, removal of the original Roanoke Street Railway Company streetcar tracks from the roadbed and a resurfacing of the pavement. Additionally, the restoration project incorporated traffic calming principles in reducing the number of vehicular travel lanes from four to two. In addition to the removal of a pair of lanes, both a median and two bike lanes were incorporated onto the bridge.

The Roanoke Apartments, also known as the Terrace Apartments, is an apartment complex listed on the National Register of Historic Places located at 1402 Maiden Lane in the Raleigh Court neighborhood of the independent city of Roanoke, Virginia, U.S.A. Designed by James F. Mactier and constructed by Paul A. Wood, the complex features seven separate buildings, each with brick facades, and is Roanoke's best example of the streamline moderne style developed in the early 1950s. Today the complex is noted for its ethnic diversity with its residents representing a wide array of religious and ethnic groups.

Fire Station No. 5 in Roanoke, Virginia is a former fire station at 216 12th Street NW, in the independent city of Roanoke. The neighborhood fire station was one of three built in 1911, and was designed to look like a house, blending into its residential neighborhood. It housed one of the city's first fire trucks to be powered by an internal combustion engine. It served the city as a fire station until 2010, when it was turned over to a local nonprofit organization.The building was listed on the National Register of Historic Places in 2011 as City of Roanoke Fire Station No. 5.

West End is a Roanoke, Virginia neighborhood located in central Roanoke south of the Norfolk Southern railyard. It borders the neighborhoods of Hurt Park and Mountain View on the west, Downtown on the east, Gilmer on the north across the Norfolk Southern railyard and Old Southwest on the south.

Hurt Park is a Roanoke, Virginia neighborhood located in central Roanoke between the Norfolk Southern railyard and the Roanoke River. It borders the neighborhoods of Cherry Hill on the west, West End on the east, Gilmer, Loudon-Melrose and Shenandoah West on the north across the Norfolk Southern railyard and Norwich across the Roanoke River and Mountain View on the south.