Southwest Historic District (Roanoke, Virginia)

The Roanoke City Health Center is a historic health care facility at 515 8th Street SW in Roanoke, Virginia. It is a modest single-story brick building in a U-shaped plan. It was built in 1951, and exemplifies trends of the period in the provision of health care to rural communities. It also exhibits features distinctive to the Jim Crow era of segregated facilities, as it was originally designed with separate areas for whites and African Americans.The building, now vacant, was listed on the National Register of Historic Places in 2016.

The Virginia Tech Carilion School of Medicine is a public medical school of Virginia Tech and located in Roanoke, Virginia. The medical school is associated with the Fralin Biomedical Research Institute. Formed as a public–private partnership with the Carilion Clinic, the medical school grants the Doctor of Medicine (M.D.) degree to its graduates. Initially a private institution from 2008-2018, the medical school became an official college of Virginia Tech in 2018.

Wasena is a Roanoke, Virginia (United States) neighborhood located in south, central Roanoke bisected by U.S. Route 221 (Main Street), immediately to the south of the Roanoke River. It borders the neighborhoods of Raleigh Court on the west, Old Southwest on the north and east and Mountain View via the Wasena Bridge across the Roanoke River on the north, and Franklin-Colonial on the south. As of the 2000 U.S. Census, Wasena has a population of 1,633 residents.

The Salvation Army Citadel is a historic religious building in Roanoke, Virginia. Built in 1941 in the Colonial Revival style, the site was the headquarters for the Salvation Army's operations in Roanoke, including church services, social services, and outreach. After the church constructed a new primary location in 1980, the building served as the Red Shield Lodge, a men's homeless shelter, until closing in 2018. It was listed to the National Register of Historic Places in 2020, and reopened that year as an apartment building.

Wasena Historic District is a national historic district located in the Wasena neighborhood of Roanoke, Virginia. It encompasses 574 contributing buildings, 1 contributing site, 3 contributing structures, and 3 contributing objects. It is a primarily residential district with single-family dwellings. Also in the district are a few commercial buildings, several industrial buildings, a park along the river and the Wasena Bridge.

Salem Avenue–Roanoke Automotive Commercial Historic District is a national historic district located of Roanoke, Virginia. It encompasses 59 contributing buildings in the southwestern part of the City of Roanoke. The district includes a variety of buildings having automotive, warehouse, light industrial and residential uses. Most of the buildings are small-scale, one or two-story brick or concrete block buildings, with the majority built between about 1920 and 1954. Notable buildings include the former Enfield Buick Dealership (c. 1930), Lindsay-Robinson & Co. Building (1918), Fulton Motor Company Auto Sales & Service (1928), Lacy Edgerton Motor Company (c. 1927), Roanoke Motor Car Company (c. 1946), and Fire Department No. 3 (1909).It was listed on the National Register of Historic Places in 2007, with boundary increases in 2008 and 2014.

Mountain View, also known as the Fishburn Mansion, is a historic home in the Mountain View neighborhood in Roanoke, Virginia. It is a 2+1⁄2-story, rectangular Georgian Revival-style house that was built in 1907. It features a colossal portico consisting of two clusters of three fluted Ionic order columns supporting an Ionic entablature topped by a pediment containing a lunette. It also has a series of one-story porches, a conservatory, and a porte cochere.It was listed on the National Register of Historic Places in 1980.

Mountain View is a Roanoke, Virginia neighborhood located in central Roanoke north of the Roanoke River. It borders the neighborhoods of Norwich on the west, West End on the east, Hurt Park on the north and Raleigh Court and Wasena on the south.In March 2011, This Old House, America’s most respected home improvement authority, selected Mountain View as Virginia’s “Best Old House Neighborhood 2011” in its annual list of “North America’s most timeless neighborhoods—places where lovingly crafted old houses have extraordinary pasts and unarguably promising futures.”Mountain View was one of 64 neighborhoods in the U.S. and Canada recognized by This Old House, which distributed nomination forms to more than 14,000 historical societies, neighborhood groups, and preservation nonprofits to compile its “biggest-ever list of off-the-beaten-path places that are worth eyeing for a great old home.”

Norfolk and Western 1218 is a preserved four-cylinder simple articulated 2-6-6-4 steam locomotive, built in June 1943 by the Norfolk and Western's (N&W) Roanoke (East End) Shops in Roanoke, Virginia as part of the N&W's class "A" fleet of fast freight locomotives. It was retired from regular revenue service in July 1959, and was later restored by Norfolk Southern for excursion service for their steam program, pulling excursions throughout the eastern United States from 1987 to 1991. It is currently on display at the Virginia Museum of Transportation in Roanoke, Virginia.

Beth Israel Synagogue (Hebrew: בית ישראל) is a Conservative synagogue located at 920 Franklin Road in Roanoke, Virginia, in the United States. The synagogue was founded in 1900, and as of 2009, it had a membership of approximately 160 families and individuals.The 1925 building, designed by Frye and Stone, combines Classical Revival features in an unusual and rather severe design. A two-story Ionic portico, with an entablature, is engaged with and centered on the stepped gabled and parapeted façade. Doors and windows occupy each of the bays between the columns. A small Star of David occupies the gable.In 2007 the synagogue completed an expansion and renovation of its building, carefully planned so that the original facade, part of Roanoke's Old Southwest historic district, was unaltered.Rabbi Fabian Werbin commenced in 2008.

The Robert E. Lee Memorial was a monument commemorating Robert E. Lee, formerly installed in Roanoke, Virginia's Lee Plaza. The stone memorial was approximately 10 feet (3.0 m) tall, and was erected by the United Daughters of the Confederacy in the fall of 1960, just as the first two black students were enrolled in the all-white school system. The monument's erection coincided with the run up to the centennial of the Civil War in 1961. In June 2020, the Roanoke City Council voted to start the legal process to remove the monument and rename Lee Plaza after the July 1, 2020 date when a new state law did away with the prohibition against removing monuments to the Confederate States of America. On just before midnight July 22, 2020, the monument was found to be torn down and broken into two pieces. A 70-year-old man named William Foreman, who was caught vandalizing the monument the night before it was torn down, was arrested on July 24, 2020, and eventually pleaded guilty to a misdemeanor. Lee Plaza was renamed Lacks Plaza after Henrietta Lacks, an African-American woman whose cells are the source of the first immortalized human cell line, and who was born in Roanoke. A statue of Lacks was unveiled in the plaza on October 4, 2023. Evergreen Burial Park submitted a proposal to the Roanoke City Council, to relocate the monument to the burial park that was accepted by the council. The proposed location for the re-erecting the statue is at the east end of the park adjacent to the flagpole dedicated to the Space Shuttle Challenger Disaster.

A statue of Henrietta Lacks was installed in Roanoke, Virginia, in 2024. The artwork was designed by Bryce Cobbs and completed by Lawrence Bechtel.