National Museum and Art Gallery, Trinidad

Memorial Park is an urban park in upper Downtown, Port of Spain, Trinidad and Tobago. Memorial Park is a public city park in commemoration of the Trinidadian veterans that served in World War I and World War II. It is one of the most visited urban parks in the city.

Bishop Anstey High School (BAHS), also known as Bishop Anstey or St. Hilary's, is a government-assisted all-girls secondary school in Port of Spain, Trinidad and Tobago. It was founded by the Anglican Bishop Arthur Henry Anstey and opened on January 13, 1921. The school is governed by a Board of Management appointed and chaired by the Bishop of Trinidad and Tobago. Its assets are controlled and managed by The Bishop Anstey Association.

Holy Name Preparatory School is a private primary school located in Port of Spain, Trinidad and Tobago. Originally associated with Holy Name Convent secondary school and Sacred Heart Boys, the school became an independent entity in 1965. It currently has around 600 students enrolled.

Port of Spain General Hospital is a public hospital in Port of Spain, Trinidad and Tobago. The main building was once a Colonial hospital that began construction in 1854, using local stone and imported brick facing to provide a Classical style facade. The official opening of the hospital was in 1858. The exterior has been maintained while the interior has been adapted for modern medical practice, mostly in work around 1960 directed by the UK architects Devereux and Davies and including murals by the Trinidadian artist Althea McNish.The hospital is located on Upper Charlotte Street in the city and serves as the main hospital for the North West Region of Trinidad, the most densely populated region in the island. Among its services are obstetric and gynecological care, outpatient medical care, surgical specialties such as orthopaedics and plastic surgery, therapeutic support and emergency care. It also serves as a teaching hospital to medical students from the University of the West Indies, St. Augustine campus. This Institution falls under the North West Regional Health Authority (NWRHA).

The College of Science, Technology and Applied Arts of Trinidad and Tobago (COSTAATT) is a public, multi-campus college in Trinidad and Tobago, established in 2000.

St. Joseph's Convent, Port of Spain is a government-assisted all-girls Roman Catholic secondary school in Port of Spain, Trinidad and Tobago. It was founded in 1836 by Sisters of St. Joseph of Cluny, and is the oldest continuous secondary school in Trinidad and Tobago. It celebrated its 180th anniversary in 2016. The school is one of the best performing schools in the Caribbean in both the Caribbean Secondary Education Certificate (CSEC) examinations and Caribbean Advanced Proficiency Examinations (CAPE) examinations. The school is governed by a Board of Management appointed and chaired by the Archbishop of Port of Spain.

St. Mary's College (CIC, which stands for College of the Immaculate Conception) is a government-assisted selective Catholic secondary school located in Port of Spain, Trinidad and Tobago.

The National Academy for the Performing Arts (NAPA) is a cultural and performing arts complex located in Port of Spain, Trinidad and Tobago. Established in 2009, NAPA serves as a hub for the development and promotion of the performing arts in the country, providing facilities for education, rehearsals, and performances. NAPA’s contribution to the cultural landscape of Trinidad and Tobago has been recognized with multiple awards. It has garnered praise not only for its architectural design but also for its impact on the local arts scene.

The Embassy of the United States in Port of Spain is the diplomatic mission of the United States of America in Trinidad and Tobago. Since the inception of diplomatic ties in 1962, Trinidad and Tobago has become one of the most industrialized nations in the English-speaking Caribbean. The embassy processes about 36,000 visa applications per year.

Port of Spain, officially the City of Port of Spain (also stylized Port-of-Spain), is the capital of Trinidad and Tobago and the third largest municipality, after Chaguanas and San Fernando. The city has a municipal population of 49,031 (2022 census), an urban population of 545,045 (2023 estimate) and a transient daily population of 250,000. It is located on the Gulf of Paria, on the northwest coast of the island of Trinidad and is part of a larger conurbation stretching from Chaguaramas in the west to Arima in the east with an estimated population of 600,000.The city serves primarily as a retail and administrative centre and it has been the capital of the island since 1757. It is also an important financial services centre for the Caribbean and is home to two of the largest banks in the region. The Piarco International Airport is the main airport on the island, connecting the capital to various major global destinations. Port of Spain was also the de facto capital of the short-lived West Indies Federation, which united the Caribbean. The city is also home to the largest container port on the island and is one of several shipping hubs of the Caribbean, exporting both agricultural products and manufactured goods. Bauxite from Guyana is trans-shipped via facilities at Chaguaramas, about 8 kilometres (5 mi) west of the city. The pre-lenten Carnival is the city's main annual cultural festival and tourist attraction. Today, Port of Spain is a leading city in the Caribbean region. Trinidad and Tobago hosted the Fifth Summit of the Americas in 2009, whose guests included US President Barack Obama and US Secretary of State Hillary Clinton.Port of Spain is also home to the biggest and most successful stock exchange in the Caribbean, the Trinidad and Tobago Stock Exchange (TTSE). The Nicholas Tower, as well as other skyscrapers, are well known throughout the region. These buildings dominate the city's skyline. Some of the tallest skyscrapers in the Caribbean are located in Port of Spain.

Saint James is a district of Port of Spain, Trinidad and Tobago. Port of Spain's last major municipal expansion occurred in 1938, when the St. James district north of Woodbrook and west of St. Clair was incorporated into the city limits. In the late 19th century, Indian indentured labourers on nearby sugar estates established houses here, and St. James gradually became the centre of Port of Spain's Indian population, with many streets named after cities and districts in British India. Western Main Road, the area's major thoroughfare, has long been the city's main nightlife district, sometimes nicknamed "the city that never sleeps". Long Circular Road, which curves north from Western Main Road then east to meet Maraval Road, forms part of the city boundary. Its "circle" encloses Flagstaff Hill, a small rise with the US ambassador's residence at its summit, which lends its name to an area of apartment buildings at its southern foot. South of St. James and near the seashore at Invaders Bay is Mucurapo, a mostly residential district which also contains the city's second-largest cemetery.

The Trinidad Regional Virus Laboratory (T.R.V.L.) was established in Port of Spain, in 1953 by the Rockefeller Foundation in co-operation with the Government of Trinidad and Tobago. It was originally housed in an old wooden army barracks near the docks in Port of Spain. A large wired-in "animal house" was built out back to house the many wild animals brought in for study. The Virus lab's first Director was the renowned epidemiologist, Dr Wilbur Downs who served in that role until 1961. In that year the laboratory was moved to new buildings at Federation Park, Port of Spain and, in 1964, became part of the Department of Microbiology of the University of the West Indies under the direction of Dr Leslie Spence, who had been with the laboratory since 1954. It is now part of the Caribbean Epidemiology Center (Carec) in Port of Spain.