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Union Race Course was a horse racing track opened in the 1850s in San Francisco, California located in the Mission District. There were two horse race courses in the Mission District at this time, the other being Pioneer Race Course which was located a few blocks away. At the time it was planned to be built, no streets existed in this neighborhood but later it appears to be bound by 19th St to 23rd St and Capp St to Harrison St.The half mile track was renovated in 1862, moved slightly to softer ground and renamed 'Willows Trotting Park' but the increasing value of the land for housing proved too much. The final horse race was run at Union Race Course on July 18, 1863.The positioning of this race course, as well as the earlier built race course called Pioneer Race Course appear to have affected the placement of the San Francisco-San Jose Railway.

Henry Geilfuss House is an 1882 Italian Villa style home built by architect Henry Geilfuss. The home is in San Francisco California and is on the National Register of Historic Places listings in California.

Neuralink Corporation is a neurotechnology company that develops implantable brain–machine interfaces (BMIs). Co-founded by Elon Musk, the company's headquarters is in the Pioneer Building in San Francisco sharing offices with OpenAI. Neuralink was launched in 2016 and was first publicly reported in March 2017.Since its founding, the company has hired several high-profile neuroscientists from various universities. By July 2019, it had received $158 million in funding (of which $100 million was from Musk) and was employing a staff of 90 employees. At that time, Neuralink announced that it was working on a "sewing machine-like" device capable of implanting very thin (4 to 6 μm in width) threads into the brain, and demonstrated a system that read information from a lab rat via 1,500 electrodes. They had anticipated starting experiments with humans in 2020; but have since moved that projection to 2022.Several neuroscientists and publications, including the MIT Technology Review, have criticized claims made by Musk in relation to the technology.

The Pioneer Building is a historic building in San Francisco, California. It was listed on the National Register of Historic Places in 1987, as "Pioneer Trunk Factory--C. A. Malm & Co.".The building is located at 2185-2199 Folsom and 3180 18th Streets. It previously housed the office of Stripe. As of 2020, it houses the offices of OpenAI and Neuralink.

OpenAI is an artificial intelligence (AI) research laboratory consisting of the for-profit corporation OpenAI LP and its parent company, the non-profit OpenAI Inc. The company, considered a competitor to DeepMind, conducts research in the field of AI with the stated goal of promoting and developing friendly AI in a way that benefits humanity as a whole. The organization was founded in San Francisco in late 2015 by Elon Musk, Sam Altman, and others, who collectively pledged US$1 billion. Musk resigned from the board in February 2018 but remained a donor. In 2019, OpenAI LP received a US$1 billion investment from Microsoft.

Folsom Street is a street in San Francisco which begins perpendicular to Alemany Boulevard in San Francisco's Bernal Heights district and ends perpendicular to the Embarcadero on the San Francisco Bay. For its southern half, Folsom Street runs north–south, but it turns northeasterly at 13th street. It runs through San Francisco's Bernal Heights district, Mission District, SoMa District, Yerba Buena District, and South Beach district. When the Stud, along with Febe's, opened up on Folsom Street in 1966, other gay leather bars and establishments catering to this subculture followed creating a foundation for the growing gay leather community.Since 1984, the street is home to the Folsom Street Fair, an annual BDSM and leather subculture street fair held in September in the South of Market portion of Folsom Street, which, from approximately 1975–84, was the center of San Francisco's gay and lesbian BDSM community.In 2008 and 2012, Folsom Street Events received the Large Nonprofit Organization of the Year award as part of the Pantheon of Leather Awards, although in 2012 it tied with Cleveland Leather Awareness Weekend. Then in 2015 Folsom Street Events received the Nonprofit Organization of the Year award as part of the Pantheon of Leather Awards.The San Francisco South of Market Leather History Alley consists of four works of art along Ringold Alley honoring leather culture; it opened in 2017. One of the works of art is metal bootprints along the curb which honor 28 people (including Alan Selby, founder of the store Mr. S Leather and known as the "Mayor of Folsom Street") who were an important part of the leather communities of San Francisco.

San Ho Won is a Korean restaurant in San Francisco's Mission District, in the U.S. state of California.The restaurant has received a Michelin star.

Mutiny Radio is an internet radio station operating from the Mission District of San Francisco, California. The station has an eclectic talk format, hosting local shows with interviews, as well as live performances of comedy, music, hip-hop, theater, storytelling, philosophy and poetry. Shows are streamed live online and made available in podcast form on ITunes and other platforms. Mutiny radio reports on progressive, alternative, independent news through their site. Their in-station gallery is available to local visual artists showcasing their work.

Arroyo Dolores (Spanish for Our Lady of Sorrow Creek) is a river in San Francisco, California that has been largely culverted. The only remaining portion above ground is in the Mission Creek Channel that drains into China Basin.

Osito is a restaurant in San Francisco, California. Established in late 2021, the restaurant serves American cuisine and has received a Michelin star.

The Girls Club in San Francisco, California, also known as Mission Neighborhood Capp St. Center, was built in 1911 in the Bay Area Tradition version of Shingle Style architecture. It was listed on the National Register of Historic Places in 1979. According to its NRHP nomination:"The Mission Neighborhood Capp Street Center is significant for the quality of its design and its role in the history of social movements in San Francisco. Built in 1911, the building is an excellent example of the First Bay Tradition. This regional interpretation of the Shingle Style was characterized by the use of shingles and stained wood and picturesque changes in spatial and axial arrangement. Its major practitioners were Ernest Coxhead, Willis Polk, Bernard Maybeck and Julia Morgan. The skillful execution of the design of the Mission Neighborhood Capp Street Center makes it a significant expression of this genre." The building is a two-and-a-half-story wood-frame structure. The 1911-built building with theatre was expanded by 1923 addition of a gymnasium, making a U-shaped complex. There is an inner courtyard and a brick alley way. The main entrance porch is capped with a Georgian-style broken pediment. The upper stories' surface is dark brown shingles. The theatre has small stage, a beamed ceiling and a balcony level. After a fire in the 1940s a sprinkler system was added.

El Capitan Theatre and Hotel, or The Cap, is a historic 1928 building containing a hotel, shops, and a former luxury vaudeville and movie theater in the Mission District of San Francisco, California. It has been listed by the city as a San Francisco Designated Landmark (no. 214), since March 3, 1996.