Church of St. John Nepomucene

James Ewing Hospital was a 300-bed Manhattan hospital notable for helping cancer patients. Memorial Sloan Kettering took over running James Ewing Hospital in 1968.

Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute–designated Comprehensive Cancer Centers. Memorial Sloan Kettering is affiliated with Cornell University's medical school. Its main campus is located at 1275 York Avenue, between 67th and 68th streets, in Manhattan. According to U.S. News & World Report 2021-2022 Best Hospitals, Memorial Sloan Kettering Cancer Center (MSK) has been ranked as the number two hospital for cancer care in the nation.

Maxwell's Plum was a bar at 1181 First Avenue (64th and 1st Avenue) in Manhattan. A 1988 New York Times article described it as a "flamboyant restaurant and singles bar that, more than any place of its kind, symbolized two social revolutions of the 1960s – sex and food". Owned by Warner LeRoy, it closed abruptly on July 10, 1988. It opened on April Fool’s Day, April, 1, 1966 by Warner LeRoy, son of Mervyn LeRoy the Hollywood producer (Wizard of Oz, Mister Roberts, Quo Vadis), it was initially part of his theater, providing a cafe with good wine lists and hamburgers for the 1960s swinging singles crowd. It became a favorite gathering spot and within a few years the theater was closed in 1969 to expand the cafe with a luxury dining room reminiscent of Maxim’s in Paris. Patrons enjoyed Maxwell’s Plum mixed experience of a boulevard café or a second floor majestic restaurant that overlooked the first floor singles' bar. Maxwell's Plum rose rapidly to be one of the city's top venues grossing over $5 million by the 1970s, equivalent to $20 million when adjusted for inflation, with alcohol sales contributing more than a third.It was famous for its eclectic menu ranging from chili and hamburgers to wild boar and caviar, along with its first class service without snobbery and "outlandish Art Nouveau decor – kaleidoscopic stained-glass ceilings and walls, Tiffany lamps galore, a menagerie of ceramic animals, etched glass and cascades of crystal."Warner Leroy had two original Toulouse Lautrec paintings in frames screwed into the hall wall leading from mezzanine to upstairs toilets. Two large Tiffany lamps hung over the 2 large tables on the mezzanine level, three steps up from the floor level bar & sitting area. This was during the 1st phase of Maxwell’s Plum. It soon served over 1,200 customers a day, including such celebrities as Richard Rodgers, Cary Grant, Bill Blass, Barbra Streisand and Warren Beatty, and becoming what The New York Times called "a favorite watering hole for the 'swinging singles' set." Other celebrities included: Myrna Loy, Buddy Hackett, NY Giants football players (who sat on 2nd floor area), and Vince Edwards (who played Dr Ben Casey). A second location opened in 1981 San Francisco, California, at a cost of $7 million, then soon closed. LeRoy built Potomac, a similarly themed 850-seat restaurant in Washington, D.C., the largest in the city's history, which also closed soon after opening at a cost of $9 million.LeRoy closed the Plum in 1988 when he sold the First Avenue building. In January 1989 the furnishings and contents of Maxwell's Plum were auctioned off. At the auction, the Tribeca Grill acquired the Plum’s large island bar.

The Church of St. Catherine of Siena is a Roman Catholic parish church in the Roman Catholic Archdiocese of New York, located at 411 East 68th Street, Manhattan, New York City. The parish was developed from that of St. Vincent Ferrer in 1896. It is staffed by the Dominican Fathers. The church built a two-story convent and penthouse at 416 East 69th Street, built 1957 to designs by Starrett & Van Vleck of 267 Fifth Avenue for $100,000 ($1,040,000 in current dollar terms).On May 8, 2015, the Archdiocese of New York announced the merger of parishes between St Vincent Ferrer and St. Catherine of Siena Church. Both churches remain open.

The New York Blood Center (NYBC) is a community, nonprofit blood bank based in New York City. Established in 1964 by Dr. Aaron Kellner, NYBC supplies blood to approximately 200 hospitals in the Northeast United States. NYBC and its operating divisions also provide transfusion-related medical services to over 500 hospitals nationally. NYBC, along with its operating divisions Community Blood Center of Kansas City, Missouri (CBC), Innovative Blood Resources (IBR), Blood Bank of Delmarva (BBD), and Rhode Island Blood Center (RIBC), collect approximately 4,000 units of blood products each day and serve local communities of more than 75 million people in the Tri-State area (NY, NJ, CT), Mid Atlantic area (PA, DE, MD, VA), Missouri and Kansas, Minnesota, Nebraska, Rhode Island, and Southern New England. In addition to serving the New York City metropolitan area, New Jersey, Connecticut and Pennsylvania, in May 2014, NYBC merged its operations with Community Blood Center of Greater Kansas City (CBC). In February 2016, NYBC and CBC announced the creation of the Kansas City-based National Center for Blood Group Genomics, a new laboratory that will focus on precision testing of blood donor samples.NYBC maintains close relationships with both New York City's Police Department (NYPD) and Fire Department (FDNY). Among NYBC's largest donor groups is the NYPD, which donated more than 11,000 pints of blood through November 2015. At the same time, the FDNY participates with NYBC in the "Be The Match Program" operated by the National Marrow Donor Program (NMDP). More than 8,000 FDNY members are on the potential donor list, and 179 members have already given this life saving gift to those in need. FDNY members represent more than 10% of all NYBC bone marrow donors. Each year, at an annual induction ceremony hosted by FDNY and NYBC at FDNY headquarters, donors and their recipients meet for the first time. In 2016, Firefighter Mike Wilson was introduced to a recipient from Erie, Pennsylvania, who received his lifesaving bone marrow to treat her acute myeloid leukemia (AML), while Firefighter Frank Perdue met a recipient diagnosed with essential thrombocythemia, a rare chronic blood disorder. In 2015, firefighter Michael McCauley of Staten Island met his recipient, a United States Marine Sergeant who saw combat in Iraq, and who was subsequently diagnosed with acute myeloid leukemia (AML). Through FDNY’s participation in NYBC’s program, McCauley’s bone marrow is credited with saving the recipient's life.NYBC houses Lindsley F. Kimball Research Institute and the Howard P. Milstein National Cord Blood Center, a public cord blood bank named after board member Howard Milstein. The National Cord Blood Program (NCBP), directed by Dr. Pablo Rubinstein, is the oldest and largest in the world. In August 2015, the NCBP announced a new collaboration with the University of California, Davis Health System to manufacture specialized lines of highly adaptable stem cells for potential new therapies for diseases that include anemia, leukemia, lymphoma, sickle cell disease and severe combined immunodeficiency.The Lindsley F. Kimball Research Institute (LFKRI) has been awarded grants to conduct research in such areas as epidemiology and the development of HIV self-testing interventions, cellular therapy and transfusion medicine, in vitro platelet production, blood genomics, immunology, the development of infectious disease screening techniques and preventions for diseases like severe acute respiratory syndrome, Hepatitis B and Hepatitis C.

The Julia Richman Education Complex (JREC) is an educational multiplex located in the Upper East Side neighborhood of Manhattan, New York City. Named after the district superintendent of schools, Julia Richman, it houses six autonomous small schools for approximately 1,800 Pre-K through 12th grade students in the former building of Julia Richman High School, a comprehensive high school that operated until 1995. The schools are operated by the New York City Department of Education.

The First Hungarian Reformed Church of New York (Hungarian: New York-i Első Magyar Református Egyház) is located on East 69th Street in the Upper East Side of the New York City borough of Manhattan. It is a stucco-faced brick building, completed in 1916 in a Hungarian vernacular architectural style, housing a congregation established in 1895. It is the only Christian religious building designed by Hungarian-born architect Emery Roth, later known for his apartment buildings on Central Park West. As one of two Hungarian Reformed Churches in Manhattan, it has been a focal point for the city's Hungarian-American community since its construction. In 1983, its parsonage was listed on the National Register of Historic Places as a contributing property to the Rowhouses at 322–344 East 69th Street historic district to its immediate west. The parsonage was listed in its own right along with the church in 2000. Following the demolition of the German Evangelical Reformed Church a block to the south, it became the oldest church in the neighborhood.

The 12 rowhouses at 322–344 East 69th Street are located on the south side of that street between First and Second avenues on the Upper East Side of the New York City borough of Manhattan. They are Neo-Grec brownstone structures built around 1879, in two sets designed by different architects. Together they constitute one of few remaining areas of low-rise rowhouse development in a neighborhood where many such houses have been demolished in favor of high-rises. In 1984 they were recognized as a historic district and listed on the National Register of Historic Places.

The Sephardic Academy of Manhattan (SAM) is a Jewish preschool and elementary school on the Upper East Side of Manhattan, New York City, whose plan is to provide pre-K through middle school services. The SAM School’s mission is to provide students with a universal education that emphasizes Sephardic-Judaic Culture and Torah knowledge and observance combined with the study of Sciences, Humanities and the Arts. This unique approach includes the pursuit of rigorous scholastic achievement, embraces a humane approach to learning, cultural recognition and religious humanism. It is rooted in a strong sense of Jewish identity as practiced in Classical Sephardic Heritage.Rabbi Elie Abadie, M.D., started the academy in 2010. The current executive director is Michelle Dayan. The academy is buying the six-story, 11,850-square-foot (1,101 m2) building at 150 East 74th Street, located between Third Avenue and Lexington Avenue in Manhattan and previously the home of the New York Veterinary Hospital, for $14 million. SAM bought the property to expand its programming. The school will open the new location September 2022 and be able to convert it into a school or for a nonprofit use, and will have the option of adding 23,000 square feet (2,100 m2).

The Urban Academy Laboratory High School (also known as the Urban Academy) is a small, progressive, transfer public high school located on the Upper East Side of New York City. Founded in 1986, its goal was to create a place where students could learn in a nontraditional sense. In 1995, it became one of six small schools located in the Julia Richman Education Complex. The structure of the classes is non-traditional. Teachers don't lecture; rather, they facilitate class discussions. They create their own curriculum and direct students with a focus on inquiry, critical thinking, and problem-solving. Students' primary source of information is not textbooks. Almost all classes are discussion based, with students expected to make arguments and support them with evidence, drawn either from course materials (primary and secondary texts) and/or their own experience. Urban's academic program is rigorous and college-oriented. It has been designated a U.S. Department of Education "Blue Ribbon School of Excellence" and a "New American High School National Showcase Site."As a member school of the New York Performance Standards Consortium, Urban Academy has a waiver from the New York State testing curriculum. Students must pass only the English Language Arts Regents exam, and complete six other performance-based assessments. Students must obtain 44 credits, as in every other public school in New York. Urban Academy does not offer credit recovery, and all students are required to spend a minimum of four semesters at Urban, regardless of the number of credits they enter with (most students spend more than four semesters). The school's six sports teams (Soccer, Volleyball, Basketball; boys and girls teams for each) are composed of students from Urban Academy and the other three high schools housed in the building: Vanguard High School, Talent Unlimited High School, and Manhattan International High School. Urban Academy has a selective admissions process, as one cannot simply enroll through the central New York City Department of Education office.

Talent Unlimited High School is a public high school of the performing arts located on the Upper East Side of Manhattan in New York City.

Sushi Seki (formerly, Sushihatsu) is a Japanese sushi restaurant located at 1143 First Avenue (between East 62nd Street and East 63rd Street), on the Upper East Side in Manhattan, New York City. It was established in 2002. Seki, who uses only one name and who spent five years at Sushi of Gari, is the chef and owner.Chefs such as Jean-Georges Vongerichten from Jean Georges, Eric Ripert of Le Bernadin, Daniel Boulud, and Gordon Ramsay dine at the restaurant.