James A. Walsh United States Courthouse

The J. C. Penney–Chicago Store is a historic department store building in downtown Tucson, Arizona. Built in 1903 for the Los Angeles Furniture Co, it housed J. C. Penney by July 25, 1942. In 1957, after J. C. Penney moved to the west side of Stone Avenue just north of Pennington Street, Aaronson Brothers moved in. The Chicago Store moved in after the El Paso–based department store closed in 1967. This building had the last complete original vintage interior in Downtown Tucson with stamped tin ceilings and period woodwork until it was completely gutted in 2020-2022.

The Valley National Bank Building is the oldest skyscraper in Tucson, Arizona. It was built in 1929 by Percy A. Eisen (1885–1946) and Albert R. Walker (1881–1958). It has housed administrative offices on the second floor. It has been listed on the National Register of Historic Places since September 12, 2003.

The Pima County Legal Services Building is a 20-storey government office building located in downtown Tucson, Arizona. It is the third tallest building in Tucson.

The First Hittinger Block is a historic two-story building in Tucson, Arizona. It was designed in the Italianate style, and built in 1901. It was named for Anton Hittinger, an investor who purchased the building in 1892 and erected other buildings around it. It housed the Harry A. Drachman Shoe Company, whose eponymous founder served in the Arizona Senate from 1923 to 1924. It has been listed on the National Register of Historic Places since September 12, 2003.

The Pioneer Hotel, designed by Tucson architect Roy Place, was one of Tucson's first high-rise buildings. Opened in 1929, the Spanish Revival hotel became the social center of the downtown business district. The property catered to the social elite. In the mid-20th century Harold and Margaret Steinfeld, owners of a large downtown department store, lived in the penthouse. A disastrous fire severely damaged the building in December 1970, and among the 29 victims were the Steinfelds. The building has been converted from a hotel to an office building. Though it adds a rich layer of history to the business district of downtown Tucson, the Pioneer Hotel has not been listed in the National Register of Historic Places because of "irreversible integrity changes" made in the late 1970s and early 1980s. The "modernization" included stripping the building of its ornate cast-stone entryway and adding vertical glass striping in an attempt to up-date the building to reflect design trends popular in the middle to late 20th century. Other changes included the covering of the building's rooftop terrace arcade, changing the storefront window configuration, and reconfiguration of the lobby. The building is 11 stories tall and, when it opened in 1929, it housed the largest ballroom in the country.

The Bank of America Plaza (formally Arizona Bank Plaza) is a high-rise office building which was built in 1977 and is located in downtown Tucson, Arizona. It was designed by Friedman & Jobusch and built by DEFCO Construction Company. It took over the top spot from the Pima County Legal Services Building, which was the tallest building from 1967 to 1977. It was the tallest building in Tucson from the time of its completion in 1977, until 1986, when the UniSource Energy Tower was completed. It is located at 33 North Stone Avenue, at the southwest corner of Stone Avenue and Pennington Street. The Bank of America Plaza is one of three major skyscrapers in the downtown Tucson area that compose the highest part of the city's skyline, the other two being the UniSource Energy Tower and the Pima County Legal Services Building. The government of Pima County purchased the building on May 1, 2007, for $24.1 million. After June 20, 2017, Bank of America vacated the building since its lease with Pima County for the building had expired. The building itself is not vacant, and Bank of America only moved its Tucson regional management to a farther north location. After Bank of America's departure, the county refers to the building by its street address.

MacArthur Building, Tucson is a three-story, 22,661-square-foot building in downtown Tucson, Arizona. It was originally named the Hotel Heidel in 1907 and was remodeled into the MacArthur Hotel in 1944. The hotel included a restaurant, saloon and barbershop and was built to serve passengers arriving via the Southern Pacific Railroad Depot. The hotel closed in 1979 and was renovated for office use in 1985.The city bought the MacArthur Building for $2.9 million in 2005 for possible use in the Depot Plaza housing project immediately to the south, but the property was not incorporated. In 2008, the city sold the building to Madden Media.

Skrappy's was a youth-run, youth-oriented performing arts and after-school center as well as an all-ages music venue, performance space and community hub in downtown Tucson, Arizona. It was billed as a drug-free, positive environment that encouraged expression and youth culture. It offered live music, and classes in music, film and theater, break dancing, visual art, printing, karate, literacy, GPS mapping, sewing and fashion design photography, writing, publishing, activism, organizing, civic engagement and empowerment.

One South Church (formally United Bank Tower and UniSource Energy Tower) is a 23 story office building located in Tucson, Arizona. At 23 stories high, One South Church is the tallest building in Tucson, and is a prominent fixture in the city's skyline. "The Tower", or the "Copper Building" as it is often referred to by locals, is home to a variety of office tenants, including New York Life, Regus, and some of Arizona's largest law firms. The building has its own parking garage located underneath the building. The building was designed by Fentress Bradbrum Associates of Denver as one of two twin towers in a city center complex. The second tower was never built. Developers of the project were Reliance Development Group of New York and Venture West Group of Tucson. Construction started in 1985 M. M Sundt Construction Company of Tucson was the general contractor. When opened in 1986 the building was known as the United Bank Tower. It was later known as the UniSource Energy Tower In October 2015, One South Church was acquired by local ownership group 1SC Partners, LLC, managed by Zach Fenton of ZFI Holdings, LLC.

The Hotel Congress is a federally-recognized historic building located in downtown Tucson. It was built in 1918 and designed by the Los Angeles architectural firm William and Alexander Curlett as part of an expansion of Congress Street and in conjunction with the theatrical venue Rialto Theatre, which sits north of Congress Street. The rear of the building faces the historic Amtrak Southern Pacific train station, built by Southern Pacific in 1907. In addition to being a hotel, the Hotel Congress building also houses a restaurant, bar and music venue. The name "The Congress Hotel" was chosen through a naming competition organized by the Arizona Daily Star newspaper in 1918. The winning suggestion was announced on April 30, 1918, and it was submitted by Dorit Dinkel, who won $15 worth of baby bonds for having their name chosen. The Hotel Congress and its owners since 1985, Richard Oseran and Shana Oseran, have been a key cultural institution and boosters in the early 21st Century redevelopment of Downtown Tucson.The Hotel is known for being the site of the capture of gangster and bank robber John Dillinger in 1934. After a series of bank robberies, the Dillinger Gang arrived in Tucson to hide out. On January 22, 1934, a fire started in the basement and spread up to the third floor, where the gang resided under aliases. After the desk clerk contacted them through the switchboard the gang escaped by aerial ladders. On the request of the gang, two firemen retrieved their luggage, identifying who they were. After being transferred to a jail in Crown Point, Indiana, Dillinger escaped again and was eventually shot down in Chicago, Illinois. Local Tucson architect Roy Place rebuilt the upper floor in the same style as the original. A historic plaque on the south entrance of the hotel bears Place's name so it is often believed to be of his original design. The Hotel Congress building was added to the National Historic Register in 2003. The Hotel Congress received a Fodor's Choice distinction award in 2006 and again in 2008. According to the National Registration listing, Alexander and William Curlett, Curlett and Son Architects of Los Angeles were the actual designers/architects. A newspaper article from the Arizona Daily Star, dated April 23, 1920, reported:"A. E. Carlette (Curlett), architect of Los Angeles, was a visitor in Tucson yesterday stopping at the Santa Rita. Mr Carlette (Curlett) was the designer of the new Rialto Theatre and the Congress Hotel."

Broadway in Tucson/A Nederlander Presentation is part of the nationally recognized Nederlander Producing Company of America. The Nederlander organization was awarded a contract by the City of Tucson in 2003 to present a series of Broadway musicals and special events downtown at the Tucson Music Hall and Leo Rich Theater, all of which are part of the Tucson Convention Center. Since 2003 Broadway In Tucson has been responsible for bringing over 25 Broadway shows to downtown Tucson. February 18, 2010 marked the press release stating that Broadway in Tucson will be bringing the smash Broadway hit Wicked to Tucson, as a part of its 2010–2011 season. For the first time ever, a Broadway in Tucson show will be held at University of Arizona's Centennial Hall. This presentation of Wicked is co-sponsored by UApresents; subsequently this represents the first partnership between the two organizations.

The Cathedral of Saint Augustine (Spanish: Catedral de San Agustín) is the mother church of the Roman Catholic Diocese of Tucson. It is located in Tucson, Arizona.