Paynes Prairie Preserve State Park

The La Chua ranch was the largest cattle ranch in Spanish Florida in the 17th century. Cattle ranching became an important part of the economy of Spanish Florida over the course of the 17th century. The La Chua ranch was founded in the middle of the 17th century, and by the end of that century accounted for one-third of the cattle in the colony. Raids by the English of the Province of Carolina and their native allies led to the abandonment of the La Chua ranch early in the 18th century.

Bivens Arm is a body of water in Gainesville, Florida. Located west of U.S. Route 441 and south of Archer Road, it is a part of Paynes Prairie. Bivens Arm is a small shallow lake covering approximately 189 acres (76 ha) in southwest Gainesville. Bivens Arm is a unique environment, which supports a wide diversity of plant and animal life in an urban setting. Tumblin Creek, which is fed by small springs and seeps, drains into Bivens Arm and is the primary source of drainage into the lake. Bivens Arm overflows onto Paynes Prairie and eventually discharges to the aquifer via Alachua Sink.

The Gainesville Sun (ISSN 0163-4925) is a newspaper published daily in Gainesville, Florida, United States, covering the North-Central portion of the state.

The Boulware Springs Water Works is a historic site in Gainesville, Florida, United States. It is located at 3400 Southeast 15th Street. On June 20, 1985, it was added to the U.S. National Register of Historic Places. It is also the western terminus of the Gainesville-Hawthorne State Trail. The spring was the site of an 1854 meeting where area citizens voted to create a new town (Gainesville) to replace Newnansville as the Alachua County seat. The spring was the source of city water until 1913 and was important in the city's growth. The University of Florida moved from Lake City to Gainesville in 1901 because the city promised the university free water for life, from the Boulware Springs. The University of Florida still does not pay for water, even though the springs are no longer used in Gainesville's water system.

Swamp Head Brewery is a brewery in Gainesville, Florida.

WXJZ (100.9 FM) is a commercial radio station in Gainesville, Florida, broadcasting to the Gainesville-Ocala, Florida area. The station is owned by MARC Radio Group Gainesville, LLC and broadcasts a classic hits format branded as "Classic Hits 100.9".

UF Health Shands Cancer Hospital is an academic cancer center in Gainesville, Florida. The 200 bed complex focuses on producing basic laboratory findings that will ultimately be used for preventive therapies for cancers.

The Emerging Pathogens Institute (EPI) is an interdisciplinary research institution associated with the University of Florida. The institute focuses on fusing key disciplines to develop outreach, education, and research capabilities designed to preserve the region's health and economy, as well as to prevent or contain new and re-emerging diseases. Researchers within the institute work in more than 30 different countries around the world, with over 250 affiliated faculty members stemming from 11 University of Florida colleges, centers, and institutes. The 90,000-square-foot building includes laboratories and collaborative space for bioinformatics and mathematical modeling.

P. K. Yonge Developmental Research School is a K-12 public laboratory school of the University of Florida, in Gainesville, Florida, United States. The student population, selected by lottery, mirrors the demographics of the school-age population of the State of Florida.

Cancer and Genetics Research Complex at the University of Florida is an interdisciplinary research center. The goal of this facility is to harness the faculty & researchers from varying departments at the University of Florida to make exciting new discoveries, and to transfer cutting edge technology to the marketplace. The Complex also houses the UF Genetics Institute (UFGI), the UF Health Cancer Center, the UF Interdisciplinary Center for Biotechnology Research, and the C.A. Pound Human Identification Laboratory, an internationally known laboratory for research and consulting in forensic anthropology.

The University of Florida College of Medicine is the medical school of the University of Florida. It is part of the J. Hillis Miller Health Science Center, with facilities in Gainesville and Jacksonville, Florida. The school grants Doctor of Medicine (M.D.), Doctor of Medicine-Doctor of Philosophy (M.D.-Ph.D.), and Physician Assistant (P.A.) degrees to its graduates. Its primary teaching hospital is UF Health Shands Hospital with which the school shares a campus in Gainesville.

The Helyx Bridge, unofficially dubbed the DNA Bridge, is a pedestrian and bicycle overpass located in Gainesville, Florida. It crosses over U.S. Route 441 (US 441).