Mill Mountain Zoo

The Roanoke Star, also known as the Mill Mountain Star, is the world's largest freestanding illuminated man-made star. It was constructed at the top of Mill Mountain in Roanoke, Virginia in 1949 by the local merchants association to draw publicity and trade to the city. The star was initially intended to be lit only during Christmas seasons, but was popular enough with the citizens of Roanoke that it is illuminated every night year-round. It stands 88.5 feet (27.0 m) tall and weighs 60,000 pounds (27,000 kg), rests 846 feet (258 m) above the city of Roanoke, and is visible for 60 miles (97 km) from the air. Its 2,000 feet (610 m) of neon tubing are typically lit entirely in white, but have the ability to shine solely in red (historically for tragic events), or in red, white, and blue (for patriotic holidays). The star has become a symbol of Roanoke and the source of its nickname "Star City of the South", and it along with its accompanying scenic overlook are popular tourist destinations in the area.

The Crystal Spring Steam Pumping Station is a historic pumping station located at Roanoke, Virginia, in the United States. It was built in 1905, and is a one-story building constructed in common-bond brick. The building houses a Corliss-type pump made by the Snow Steam Pump Company in Buffalo, New York. At its peak, the pump provided 5,000,000 US gallons (19,000 m3) of water daily. It was in operation from 1905 to 1957, and was an important source of fresh water in Roanoke's early history. The pump and building underwent a renovation in 1976, and the property was listed on the National Register of Historic Places in 1980. As of 2023 the building was open for tours during summer weekends.

South Jefferson is a Roanoke, Virginia neighborhood located in southeast Roanoke, surrounded roughly by the Roanoke River to the south and east and the Roy L. Webber Expressway to the west, centered on South Jefferson Street. It borders the neighborhoods of Old Southwest on the west, Belmont and Downtown on the north, and Riverland/Walnut Hills via the Walnut Street Bridge on the east.

Victory Stadium was an American football stadium located in Roanoke, Virginia. It opened in 1942 and was demolished in 2006.

The Riverland Historic District encompasses an early 20th century neighborhood on the south side of the Roanoke River in Roanoke, Virginia. The area consists of a portion of the residential area bounded on the south by Walnut Avenue SE, on the east by Arbutus Avenue SE, and on other sides by the river. Most of the included properties are either on Arbutus Avenue or Riverland Street, with some also on Piedmont Street and Walnut Avenue. The neighborhood is one of closely spaced residential properties built to provide housing for workers in nearby businesses. It was developed by the Highland Land Company, and was mostly built out between 1900 and 1930.The district was listed on the National Register of Historic Places in 2013.

The Roanoke River and Railroad Historic District is a predominantly industrial area on the north side of the Roanoke River in Roanoke, Virginia. The area is bounded by South Jefferson Street on the west and the Roanoke River to the east, and extends north as far as Albemarle Avenue. The district's resources are defined primarily by their relationship to the railroad tracks that bisect this area. The area was developed in the late 19th and early 20th centuries with the completion of the Roanoke & Southern line in 1892 and the Virginian Railway line in 1909, and consists primarily of functional industrial buildings that were built between about 1900 and 1930, an example of which is the Virginia Can Company (built in 1912, listed on the National Register of Historic Places in 2006). Notable exceptions are the Virginian Railway Passenger Station, a Spanish Revival passenger station built 1909-10 and listed on the National Register of Historic Places since 2003, and the Walnut Street and Jefferson Street bridges, completed in 1927 and 1928, respectively. Both bridges were constructed in the Art Deco style and designed with "Egyptian Babylonian" style decorations.Many of the former industrial buildings located in the district have been demolished as part of a city-led redevelopment plan. Sixteen remaining structures contribute to the historic district, which was listed on the National Register of Historic Places in 2013.

The Virginian Railway Passenger Station, also known as the Virginian Station is a former rail station listed on the National Register of Historic Places in the South Jefferson neighborhood of the independent city of Roanoke, Virginia, U.S.A. Located at the intersection of Jefferson Street SE (VA 116) and Williamson Road, the Virginian Station served as a passenger station for the Virginian Railway between 1910 and 1956. The station was the only station constructed with brick along the entire length of the Virginian's 608 miles (978 km) network. It was severely damaged by fire on January 29, 2001.

Boxley–Sprinkle House is a historic home located at Roanoke, Virginia. It was built in 1907, and is a two-story, five-bay, Colonial Revival style brick dwelling. It has a central projecting bay, full height entrance portico and hipped roof. The house was originally constructed in the Victorian style, with the entrance facing 26th Street (then 5th Avenue) with a corner turret, projecting polygonal bays and a wraparound porch. In the 1940s, the house was redesigned in the Colonial Revival style and the entrance was changed to face Crystal Spring Avenue.It was listed on the National Register of Historic Places in 2004.

The American Viscose Plant Historic District is an industrial park and historic district located in Roanoke, Virginia. The site is the location of the former American Viscose Corporation rayon processing plant that once employed over 5,000 and for a time was reportedly the largest rayon producing mill in the world. The plant's construction began in 1916 with the building of the first of what became three large processing plants of two spinning units each; the second began construction in 1921 and the third in 1925. With the plant's viability decreased by newer facilities elsewhere and rayon's usage supplanted by nylon and other synthetic fabrics, the factory closed in 1958. The property was purchased by an assortment of Roanoke investors in 1961 and has been operated as an industrial park since. The district consists of 20 contributing resources, including 16 buildings, two structures, and two sites. It was listed on the National Register of Historic Places in 2019. As of 2023, it was in the early stages of redevelopment into a mixed-use district of residential and commercial use.

Virginia Can Company-S.H. Heironimus Warehouse is a historic factory and warehouse complex located at Roanoke, Virginia. The U-shaped complex was built in 1912, and consists of an office and two factory buildings. All three of the buildings are two stories in height and are constructed of brick on a raised foundation of poured concrete. A second-story pedestrian bridge connects the two factory buildings and a brick hyphen connects the office building to the north factory building. The complex was built for the Virginia Can Company, the first and largest manufacturer of tin cans in Roanoke, Virginia. After 1951, it housed a clothing factory and then the Heironimus department store warehouse.It was listed on the National Register of Historic Places in 2006, and included in the Roanoke River and Railroad Historic District in 2013. It is located in the Virginia Landmarks Register listed Southeast Roanoke Historic District.

South Roanoke is a neighborhood located in southeast Roanoke, Virginia, surrounded roughly by the Roanoke River to the north and Mill Mountain to the east, centered on Crystal Spring Avenue. It borders the neighborhoods of Southern Hills on the south, South Jefferson on the north, and Mill Mountain on the east and Franklin-Colonial on the west.

Jefferson College of Health Sciences (JCHS and Jefferson College) was a private health sciences college in Roanoke, Virginia. Officially chartered as a college in 1982, Jefferson College is the oldest hospital-based college in Virginia. In 2019, the college merged with Radford University to become Radford University Carilion. Jefferson College of Health Sciences had approximately 1,062 students based on the enrollment statistics from fall 2015 (81% female, 19% male) who represented approximately 31 states. The college offered 15 majors in various healthcare disciplines. Jefferson College of Health Sciences awarded the Associate of Science, Bachelor of Science, Master of Science and Doctoral degrees.