Virginian Railway Passenger Station (Roanoke, Virginia)

The Roanoke River and Railroad Historic District is a predominantly industrial area on the north side of the Roanoke River in Roanoke, Virginia. The area is bounded by South Jefferson Street on the west and the Roanoke River to the east, and extends north as far as Albemarle Avenue. The district's resources are defined primarily by their relationship to the railroad tracks that bisect this area. The area was developed in the late 19th and early 20th centuries with the completion of the Roanoke & Southern line in 1892 and the Virginian Railway line in 1909, and consists primarily of functional industrial buildings that were built between about 1900 and 1930, an example of which is the Virginia Can Company (built in 1912, listed on the National Register of Historic Places in 2006). Notable exceptions are the Virginian Railway Passenger Station, a Spanish Revival passenger station built 1909-10 and listed on the National Register of Historic Places since 2003, and the Walnut Street and Jefferson Street bridges, completed in 1927 and 1928, respectively. Both bridges were constructed in the Art Deco style and designed with "Egyptian Babylonian" style decorations.Many of the former industrial buildings located in the district have been demolished as part of a city-led redevelopment plan. Sixteen remaining structures contribute to the historic district, which was listed on the National Register of Historic Places in 2013.

Jefferson College of Health Sciences (JCHS and Jefferson College) was a private health sciences college in Roanoke, Virginia. Officially chartered as a college in 1982, Jefferson College is the oldest hospital-based college in Virginia. In 2019, the college merged with Radford University to become Radford University Carilion. Jefferson College of Health Sciences had approximately 1,062 students based on the enrollment statistics from fall 2015 (81% female, 19% male) who represented approximately 31 states. The college offered 15 majors in various healthcare disciplines. Jefferson College of Health Sciences awarded the Associate of Science, Bachelor of Science, Master of Science and Doctoral degrees.

Old Southwest is a neighborhood of the independent city of Roanoke, Virginia, United States. Located geographically near the center of the city, Old Southwest was annexed from Roanoke County in 1890 and developed as one of Roanoke's more affluent residential areas. Today the majority of the neighborhood falls within the Southwest Historic District listed on both the Virginia Landmarks Register and the National Register of Historic Places.

Virginia Can Company-S.H. Heironimus Warehouse is a historic factory and warehouse complex located at Roanoke, Virginia. The U-shaped complex was built in 1912, and consists of an office and two factory buildings. All three of the buildings are two stories in height and are constructed of brick on a raised foundation of poured concrete. A second-story pedestrian bridge connects the two factory buildings and a brick hyphen connects the office building to the north factory building. The complex was built for the Virginia Can Company, the first and largest manufacturer of tin cans in Roanoke, Virginia. After 1951, it housed a clothing factory and then the Heironimus department store warehouse.It was listed on the National Register of Historic Places in 2006, and included in the Roanoke River and Railroad Historic District in 2013. It is located in the Virginia Landmarks Register listed Southeast Roanoke Historic District.

Victory Stadium was an American football stadium located in Roanoke, Virginia. It opened in 1942 and was demolished in 2006.

South Jefferson is a Roanoke, Virginia neighborhood located in southeast Roanoke, surrounded roughly by the Roanoke River to the south and east and the Roy L. Webber Expressway to the west, centered on South Jefferson Street. It borders the neighborhoods of Old Southwest on the west, Belmont and Downtown on the north, and Riverland/Walnut Hills via the Walnut Street Bridge on the east.

St. John's Episcopal Church is a historic Episcopal church in Roanoke, Virginia, United States. It was built in 1891–1892, and is a Gothic style limestone church designed by Charles M. Burns of Philadelphia. The building is a nave-plan, clerestory-style church that includes a corner bell tower and a narthex and chapel in the rear. A Tudor Revival style parish house was constructed in 1923. The church's congregation is one of the city's oldest, and has included many prominent local, state, and national leaders. The church was listed on the National Register of Historic Places in 1991.

Beth Israel Synagogue (Hebrew: בית ישראל) is a Conservative synagogue located at 920 Franklin Road in Roanoke, Virginia, in the United States. The synagogue was founded in 1900, and as of 2009, it had a membership of approximately 160 families and individuals.The 1925 building, designed by Frye and Stone, combines Classical Revival features in an unusual and rather severe design. A two-story Ionic portico, with an entablature, is engaged with and centered on the stepped gabled and parapeted façade. Doors and windows occupy each of the bays between the columns. A small Star of David occupies the gable.In 2007 the synagogue completed an expansion and renovation of its building, carefully planned so that the original facade, part of Roanoke's Old Southwest historic district, was unaltered.Rabbi Fabian Werbin commenced in 2008.

The Riverland Historic District encompasses an early 20th century neighborhood on the south side of the Roanoke River in Roanoke, Virginia. The area consists of a portion of the residential area bounded on the south by Walnut Avenue SE, on the east by Arbutus Avenue SE, and on other sides by the river. Most of the included properties are either on Arbutus Avenue or Riverland Street, with some also on Piedmont Street and Walnut Avenue. The neighborhood is one of closely spaced residential properties built to provide housing for workers in nearby businesses. It was developed by the Highland Land Company, and was mostly built out between 1900 and 1930.The district was listed on the National Register of Historic Places in 2013.

USS Roanoke (CL-145) was the second ship of the Worcester-class light cruisers completed for the U.S. Navy shortly after the end of World War II. Commissioned in 1949, she served in the Atlantic, Mediterranean and Pacific before being decommissioned in 1958. She was sold for scrap in 1972.

The Patrick Henry Hotel is a Colonial Revival former hotel listed on both the National Register of Historic Places and the Virginia Landmarks Register in Downtown Roanoke, Virginia, United States. Located at 617 South Jefferson Street at the southern end of Downtown, the Patrick Henry was designed by William Lee Stoddart and opened in 1925. The building now serves as apartments, office space, and a restaurant in the former lobby rebranded simply The Patrick Henry. It is located in the Roanoke Downtown Historic District.

The Boxley Building is a historic commercial building located in Roanoke, Virginia. It was built in 1922, during a wave of post-World War I construction in the city. The building is eight stories, and follows a pattern set by other skyscrapers of the time in consisting of three sections similar to a classical column. The bottom section, or pedestal, is one story fronted with granite; the middle section, or shaft, consists of the next six stories built with beige enameled brick; the top section, or capital, is the eighth story fronted with richly decorated terra cotta panels topped with a finely detailed copper cornice.The building was commissioned by William Wise Boxley, a local builder and developer who was Roanoke's mayor at the time of construction. Boxley was an influential figure in the city, having played a significant role in the founding of the Shenandoah Life Insurance Company and Colonial American Bank as well as sitting on the boards of both Roanoke College and Virginia Military Institute. Boxley was elected to the Roanoke City Council in 1918, and the following year was appointed the city's first mayor under its new council-manager form of government.: 552  The building's architect was Edward G. Frye, whose firm had previously erected the Roanoke Times building, the city's municipal building, and would complete Roanoke's new market building in the same year as the Boxley.: 500, 504, 586 Boxley's building materials company was one of the original tenants of the building, and remained headquartered there until vacating in 2005. The building was empty from the late-2000s until being purchased by a local developer in 2016. The building's offices were converted into residential space, with the bottom four floors used as dormitory housing for international students of two Roanoke-area parochial schools, and the top four floors converted into luxury apartments.The building was listed on the National Register of Historic Places in 1984, and it is a contributing structure to the Roanoke Downtown Historic District.