155 Mercer Street

Sartiano's is an Italian-American restaurant with locations in SoHo New York, and within Wynn Las Vegas on the Las Vegas Strip. The New York location opened in 2023 and is located within the Mercer Hotel. The Las Vegas location, titled as "Sartiano's Italian Steakhouse", opened in Wynn in March 2026, adjacent to Zero Bond.

The Mercer Hotel, located at the corner of Mercer and Prince Streets in SoHo, Manhattan, New York City, was the second acquisition in the luxury collection of André Balazs hotels. It offers 75 guest rooms on six floors of a Romanesque revival building.Opening in 1997, The Mercer is the sister hotel to Hollywood's Chateau Marmont.

The Gallery was a disco in SoHo, Manhattan which was opened in February 1972 by disc jockey Nicky Siano and his older brother Joe Siano. The first location of The Gallery, located on 132 West 22nd Street, closed in July 1974. It reopened in November 1974 at 172 Mercer and Houston Streets and closed in October 1977. Famed DJs Larry Levan and Frankie Knuckles both worked at the club, but not at the DJ booth. Grace Jones and Loleatta Holloway both made their debut performances at The Gallery.

Mercer Street is a street in the New York City borough of Manhattan. It runs north to south through Greenwich Village and SoHo neighborhoods, from East 8th Street past West Houston Street to Canal Street. The street was previously called First Street and Clermont Street, but was renamed in 1799 for Hugh Mercer, a Scottish-American brigadier general who died at the Battle of Princeton, which came about due to his advice to George Washington to march on Princeton. Its coordinates are 40°43′32.24″N 73°59′51.99″W

The Terrain Gallery, or the Terrain, is an art gallery and educational center at 141 Greene Street in SoHo, Manhattan, New York City. It was founded in 1955 with a philosophic basis: the ideas of Aesthetic Realism and the Siegel Theory of Opposites, developed by American poet and educator Eli Siegel. Its motto is a statement by Siegel: "In reality opposites are one; art shows this."

Fanelli Cafe is a historic New York City restaurant and bar considered the city's second-oldest food-and-drink establishment in the same locale, having operated under various owners at 94 Prince Street since 1847. It served as a gathering place for artists during the transition of Manhattan's SoHo neighborhood from a manufacturing area to an arts community.

109 Prince Street at the corner of Greene Street – where it is #119 – in the SoHo neighborhood of Manhattan, New York City is a historic cast-iron building. It was built in 1882-83 and was designed by Jarvis Morgan Slade in the French Renaissance style. The cast-iron facade was provided by the architectural iron works firm of Cheney & Hewlett. The building, originally a store, has been described as one of the most striking gems of the 19th century cast iron architecture in the world. Completely restored in 1993 by architecture firm Kapell & Kostow, it was awarded the prestigious Landmark Certificate of Merit by the New York City Landmarks Preservation Commission in 1994. It is located within the SoHo - Cast Iron Historic District.

The Scholastic Building is the 10-story headquarters of the Scholastic Corporation, located on Broadway between Prince and Spring Streets in the SoHo neighborhood of Manhattan, New York City. Built in 2001, it was the first new building to be constructed in the SoHo-Cast Iron Historic District, replacing a one-story garage built in 1954. It is the only building in New York ever to be designed by Italian architect, Aldo Rossi. Originally conceived of in his New York office, it was completed and refined by disciple of his, Morris Adjmi. It is respectful of the neighboring buildings and pays homage to the district's cast iron architectural identity. The cast iron architecture that defines this neighborhood straddles between the classical and industrial periods of New York's past. According to historian William Higgins, "the building’s columnar Broadway façade, in steel, terra-cotta, and stone, echoes the scale and the formal, Classical character of its commercial neighbors. The rear façade, on Mercer Street, extracts a gritty essence from its more utilitarian surroundings of plain cast iron and weathered masonry." The Scholastic Building was designed and assembled using a "kit of parts" methodology, which is similar to a time when the facades of SoHo's cast-iron buildings were built by ordering the building elements and ornaments in parts from a catalog, having them cast off-site in foundries, and assembled on site.

Prince Street is a historic street in SoHo, Manhattan, known for its historic architecture and high-end boutiques. Prince Street runs approximately 0.6 miles (0.97 km) from Sixth Avenue to the Bowery, crossing Broadway. The street has been the location of historical landmarks, such as St. Patrick's Cathedral in the 1850s. 203 Prince Street is a historic townhouse built in 1834 that is listed on the National Register of Historic Places. Prince Street Pizza is highly popular pizzeria famous for its Sicilian "SoHo" squares and pepperoni slices.

The Guggenheim Museum SoHo was a branch of the Guggenheim Museum designed by Arata Isozaki that was located at the corner of Broadway and Prince Street in SoHo, Manhattan, New York City. The museum opened in 1992 and closed in 2001 after hosting exhibits that included Marc Chagall and the Jewish Theater, Paul Klee at the Guggenheim Museum, Robert Rauschenberg: A Retrospective, and Andy Warhol: The Last Supper, which served as a key part of the museum's permanent collection. The closing was initially hoped to be temporary, but the museum closed permanently in 2002.Initial attendance was forecast to be 250,000 visitors a year, but the museum drew between 125,000 and 200,000 its first year, and attendance did not increase in subsequent years. The museum restructured in 1999 to shrink its exhibition space from 27,000 to 20,000 square feet to reduce its operating costs.

The Prince Street station is a local station on the BMT Broadway Line of the New York City Subway. Located in SoHo, Manhattan, it is served by the R train at all times except late nights, the W train on weekdays, the N train during late nights and weekends, and the Q train during late nights. The station opened in 1917, had its platforms extended in the late 1960s, and was renovated in the late 1970s and in 2001.

Greene St. Recording was a New York City recording studio, located at 112 Greene Street in SoHo, Manhattan, until its closure in 2001. It was one of the early headquarters of hip hop music during the 1980s and 1990s.