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The Renaissance Center (also known as the GM Renaissance Center and nicknamed the RenCen) is a group of seven connected skyscrapers in Downtown Detroit, Michigan, United States. The Renaissance Center complex is on the Detroit International Riverfront and is owned and used by General Motors as its world headquarters. The central tower has been the tallest building in Michigan since it was erected in 1977. John Portman was the principal architect for the original design. The first phase consisted of a five-tower rosette rising from a common base. Four 39-story office towers surround the 73-story hotel rising from a square podium which includes a shopping center, restaurants, brokers, and banks. The first phase officially opened in March 1977. Portman's design brought renewed attention to city architecture, since it resulted in construction of the world's tallest hotel at the time. Two additional 21-story office towers (known as Tower 500 and Tower 600) opened in 1981. This type of complex has been termed a city within a city. In 2004, General Motors completed a US$500 million renovation of the Class-A center as its world headquarters, which it had purchased in 1996. The renovation included the addition of the five-story Wintergarden atrium, which provides access to the International Riverfront. Architects for the renovation included Skidmore, Owings & Merrill, Gensler, SmithGroup, and Ghafari Associates. Work continued in and around the complex until 2005. Renaissance Center totals 5,552,000 square feet (515,800 m2) making it one of the world's largest commercial complexes.In July 2015, the complex was re-branded as "The GMRENCEN." Its logo was modernized and "Reflecting a New Detroit" was introduced as the new tagline. A photo-journalistic advertising campaign launched to "shine a spotlight on the people in Detroit who make remarkable contributions" to the city. Despite the name, the hotel portion is not affiliated with the Renaissance Hotels chain, also owned by Marriott. An unrelated Renaissance Hotel does exist in the suburb of Novi however.

The Detroit Grand Prix (currently branded as the Chevrolet Detroit Grand Prix presented by Lear Corporation for sponsorship reasons) is an IndyCar Series race weekend held on a temporary circuit in Detroit, Michigan. The race has been held from 1989 to 2001, 2007 to 2008, and since 2012. Since 2012, the event has been scheduled for the weekend immediately following the Indianapolis 500. The origins of the event date back to the Formula One Detroit Grand Prix on the Detroit street circuit. The CART series began headlining the event in 1989, and in 1992, the race moved from downtown Detroit to Belle Isle, a park situated on an island in the Detroit River, which is the longest serving venue of the race. The IndyCar Series took over the race beginning in 2007. The race has been supported by Indy Lights and Formula Atlantic and top-level sports car series such as the Trans-Am Series and the ALMS. From 2023 the race returned to the downtown streets around the Renaissance Center using a circuit partially based on the original Detroit street circuit used by Formula One and CART. Open wheel racing in Detroit dates back to the 1920s–1950s, when AAA held the Detroit 100 at the Michigan State Fairgrounds Speedway. AAA also held one five-mile (8 km), non-championship race at Grosse Pointe in 1905. The Raceway on Belle Isle is classified as an FIA Grade Two circuit. The original Detroit Street Circuit was considered at the time an FIA Grade One circuit, while the downtown circuit is also an FIA Grade Two Circuit.

The streets of Detroit, in the U.S. state of Michigan, hosted Formula One racing, and later CART racing, between the 1982 and 1991 seasons. The street circuit (course) was set up near the Renaissance Center and the Cobo Arena, also including a small part of the M-1 highway, also known as Woodward Avenue. It is a flat circuit, with elevation ranging from 577–604 ft (176–184 m) above sea level. The circuit will be reopened in June 2023 for the IndyCar Detroit Grand Prix race with a modified and shortened layout.

Brush Street Station was a passenger train station on the eastside of downtown Detroit, Michigan, located at the foot of Brush Street at its intersection with Atwater Street and bordered by the Detroit River to the south.

Renaissance Center station is a Detroit People Mover station in Downtown Detroit, Michigan. It is located at the northeast corner of the Renaissance Center complex (whence the station takes its name), connected to Tower 200 (Northwest) at Level 2 alongside Jefferson Avenue. As it serves RenCen, the station serves the Marriott Hotel, General Motors headquarters, the Riverfront and the Wintergarden shopping center. In 2014, this stop was the second most heavily trafficked (behind only Greektown) with 487,758 riders.The People Mover shut down temporarily on March 30, 2020, due to decreased ridership amid the COVID-19 pandemic. Following the system's May 2022 restart, the station reopened on September 14, 2022.

Mariners' Church of Detroit is a church with worship services adhering to Anglican liturgical traditions located at 170 East Jefferson Avenue in Downtown Detroit, Michigan. It was founded in 1842 as a special mission to the maritime travelers of the Great Lakes and functioned as a parish of the Episcopal Diocese of Michigan until 1992, when the Michigan Court of Appeals ruled it was incorporated as an independent congregation. The church was listed on the National Register of Historic Places in 1971. The church has a non-exclusive, limited association with the REC Diocese of Mid-America which itself is a founding member of the Anglican Church in North America.The church grounds contain a bronze sculpture of George Washington wearing the apron of a master mason by Donald De Lue. The sculpture is a copy of the wax original created in 1959 and was installed in 1966.

The Charles Trombly House is located at 553 East Jefferson Avenue in Detroit, Michigan. It is more commonly known as the Beaubien House, and is currently the headquarters of the Michigan Architectural Foundation and the American Institute of Architects of Michigan. The building is one of the oldest remaining houses in Detroit, and was designated a Michigan State Historic Site in 1975 and listed on the National Register of Historic Places in 1979.

Millender Center station is a Detroit People Mover station in Downtown Detroit, Michigan. It is located inside the Millender Center complex at Level 5. It serves the Courtyard by Marriott hotel and residential apartments. The building is also connected by two separate skywalks to the Renaissance Center and the Coleman A. Young Municipal Center.

The Alexander Chapoton House is a Queen Anne style row house located at 511 Beaubien Street in Downtown Detroit, Michigan. It was listed on the National Register of Historic Places and designated a Michigan State Historic Site in 1980.

The Millender Center is a mixed-use complex in downtown Detroit, Michigan. The complex spans two city blocks, containing a retail atrium, Detroit People Mover station, and parking garage on its first seven floors, plus the 33-floor Renaissance City Club Apartments and a 20-floor Courtyard by Marriott hotel. Developed by Forest City Enterprises and completed in 1985, the Millender Center is now owned by General Motors, and integrated with GM's Renaissance Center complex across the street.

Saints Peter and Paul Jesuit Church is a Roman Catholic church located at 629 East Jefferson Avenue in Detroit, Michigan. It is the oldest existing church in the city of Detroit, and was listed on the National Register of Historic Places and designated a Michigan State Historic Site in 1971.

Ford Auditorium was a 2,920-seat auditorium in Detroit, Michigan built in 1955 and opened in 1956. Located on the Detroit riverfront, it served as a home to the Detroit Symphony Orchestra (DSO) for more than 33 years and was an integral part of the city's Civic Center. With approval from the Ford family and the city, the building was demolished in July 2011 as part of the city's waterfront redesign plans.