Annunciazione della Beata Vergine Maria a Via Ardeatina

The Sack of Rome, then part of the Papal States, followed the capture of the city on 6 May 1527 by the mutinous troops of Charles V, Holy Roman Emperor during the War of the League of Cognac. Despite not being ordered to storm the city, with Charles V intending to only use the threat of military action to make Pope Clement VII come to his terms, a largely unpaid Imperial army formed by 14,000 Germans, many of Lutheran faith, 6,000 Spaniards and some Italian contingents occupied the scarcely defended Rome and began looting, slaying and holding citizens for ransom in excess without any restraint. Clement VII took refuge in Castel Sant'Angelo after the Swiss Guard were annihilated in a delaying rearguard action; he remained there until a ransom was paid to the pillagers. Benvenuto Cellini, eyewitness to the events, described the sack in his works. It was not until February 1528 that the spread of a plague and the approach of the League forces under Odet de Foix forced the army to withdraw towards Naples from the city. Rome's population had dropped from 55,000 to 10,000 due to the atrocities, famine, an outbreak of plague and flight from the city. The subsequent loss of the League army during the siege of Naples secured a victory in the War of the League of Cognac for Charles V. The Emperor denied responsibility for the sack and was eventually absolved by Clement VII for the event. On the other hand, the Sack of Rome further exacerbated religious hatred and antagonism between Catholics and Lutherans.

The Mausoleum of Maxentius was part of a large complex on the Appian Way in Rome that included a palace and a chariot racing circus, constructed by the Emperor Maxentius. The large circular tomb was built by Maxentius in the early 4th century, probably with himself in mind and as a family tomb, but when his young son Valerius Romulus died he was buried there. After extensive renovation the mausoleum was reopened to the public in 2014.

Capo di Bove is an archaeological site on the Appian Way on the outskirts of Rome, Italy. It contains the thermal baths of a vast property owned in the 2nd century AD by Herodes Atticus and his wife Annia Regilla.

The Appian Way Regional Park is the second-largest urban park of Europe, after Losiny Ostrov National Park in Moscow. It is a protected area of around 4580 hectares, established by the Italian region of Latium. It falls primarily within the territory of Rome but parts also extend into the neighbouring towns of Ciampino and Marino.

The Tomb of Caecilia Metella (Italian: Mausoleo di Cecilia Metella) is a mausoleum located just outside Rome at the three mile marker of the Via Appia. It was built during the 1st century BC to honor Caecilia Metella, who was the daughter of Quintus Caecilius Metellus Creticus, a consul in 69 BC, and the wife of Marcus Licinius Crassus who served under Julius Caesar and was the son of the famous triumvir with the same name, Marcus Licinius Crassus. The mausoleum was probably built in 30–10 BCE by her son who also had the same name, Marcus Licinius Crassus.The Tomb of Caecilia is one of the most well known and well preserved monuments along the Via Appia and a popular tourist site. In 2013, the museum circuit of the Baths of Caracalla, Villa of the Quintilii, and the Tomb of Caecilia Metella was the twenty-second most visited site in Italy, with 245,613 visitors and a total gross income of €883,344.

San Sebastiano fuori le mura (Saint Sebastian beyond the Walls), or San Sebastiano ad Catacumbas (Saint Sebastian at the Catacombs), is a minor basilica in Rome, Central Italy. Up to the Great Jubilee of 2000, San Sebastiano was one of the Seven Pilgrim Churches of Rome, and many pilgrims still favour the traditional list (not least perhaps because of the Catacombs and because the Santuario della Madonna del Divino Amore, which replaced it in the list, is farther from the inner city).

The Catacombs of San Sebastiano are a hypogeum cemetery in Rome (Italy), rising along Via Appia Antica, in the Ardeatino Quarter. They are one of the very few Christian burial places that have always been accessible. The first of the former four floors is now almost completely destroyed.

The church of San Vigilio in Rome is a Catholic place of worship located on Via Paolo Di Dono serving the parish of that name. Its eponymous patron is Saint Vigilius of Trent. The parish was erected on 22 May 1968 by Cardinal Vicar Angelo Dell'Acqua and entrusted first to the clergy of the Archdiocese of Trento and then to the diocesan clergy of the Diocese of Rome.The building the parish uses for its liturgies is contemporary in style, designed by Studio Passarelli. Construction began in 1983 and was completed in 1993. It is built of concrete with steel supports and appears compact in volume and modest in height. The semicircular central hall has a floor that slopes down toward the sanctuary. Glass panels behind the altar open to an area for outdoor liturgies with several tiers for seating in the style of an amphitheater. The parish rectory and offices are housed above the hall.From 1992 to 1997, the parochial vicar was Rev. Augusto Paolo Lojudice, later a cardinal and Archbishop of Siena. Pope John Paul II visited the church on 7 November 1993.Pope Francis designated the parish as a titular church on 28 November 2020, appointing Jose Advincula of the Philippines as Cardinal Patron.

The Ardeatine massacre, or Fosse Ardeatine massacre (Italian: Eccidio delle Fosse Ardeatine), was a mass killing of 335 civilians and political prisoners carried out in Rome on 24 March 1944 by German occupation troops during the Second World War as a reprisal for the Via Rasella attack in central Rome against the SS Police Regiment Bozen the previous day. Subsequently, the Ardeatine Caves site (Fosse Ardeatine) was declared a Memorial Cemetery and National Monument open daily to visitors. Every year, on the anniversary of the slaughter and in the presence of the senior officials of the Italian Republic, a solemn state commemoration is held at the monument in honour of the fallen. Each year, 335 names are called out, a simple roll call of the dead, to reinforce that 335 discrete individuals symbolise a collective entity.

The Villa of Maxentius is an imperial villa in Rome, built by the Roman emperor Maxentius. The complex is located between the second and third miles of the ancient Appian Way, and consists of three main buildings: the palace, the circus of Maxentius and the dynastic mausoleum, designed in an inseparable architectural unit to honor Maxentius.

The Appian Way (Latin and Italian: Via Appia) is one of the earliest and strategically most important Roman roads of the ancient republic. It connected Rome to Brindisi, in southeast Italy. Its importance is indicated by its common name, recorded by Statius, of Appia longarum... regina viarum ("the Appian Way, the queen of the long roads"). The road is named after Appius Claudius Caecus, the Roman censor who began and completed the first section as a military road to the south in 312 BC during the Samnite Wars.

The Circus of Maxentius (known until the 19th century as the Circus of Caracalla) is an ancient structure in Rome, Italy, part of a complex of buildings erected by emperor Maxentius on the Via Appia between AD 306 and 312. It is situated between the second and third miles of the Via Appia, between the basilica and catacombs of San Sebastiano and the imposing late republican tomb of Caecilia Metella, which dominates the hill that rises immediately to the east of the complex. It is part of the Appian Way Regional Park.