Peruna Drug Manufacturing Company Building

The Columbus Bus Station is an intercity bus station in Downtown Columbus, Ohio. The station, managed by Greyhound Lines, also serves Barons Bus Lines, Miller Transportation, GoBus, and other carriers. The current building was constructed in 1969. Since 1979, with the demolition of Union Station and a short-lived replacement, the Greyhound station has been the only intercity transit center in the city. Columbus has seen intercity bus transit since 1929, when a union station opened on Town Street. Sixteen companies, including a Greyhound bus company, operated there. In 1932, a competing bus terminal opened on State Street, operated by Greyhound. By 1940, the station was replaced by another Greyhound terminal, in a space neighboring the current bus station site. The 1940 terminal was lauded at its opening, though in following decades, it reportedly deteriorated and became a place of refuge for the homeless. The current bus station was built from 1968 to 1969 in a modern style, and featured numerous traveler amenities. Efforts to keep the station safe were successful early on, though the Greyhound Corporation proposed its sale by 1988. In 2021, following a shooting incident and reports of frequent police visits, the property was declared a public nuisance. Agreements were made to increase security, and the local mass transit agency, COTA, agreed to purchase and redevelop the site. Intercity bus services will move to a COTA facility in late 2021, and COTA plans to demolish the 1969 station and create a mixed-use development on the property.

Central Market was a public market in Downtown Columbus, Ohio. The market operated from 1814 to 1966, was the location of Columbus's first city hall for two decades, from 1850 to 1872. It moved three times, each time into successively larger buildings. The third market building stood the longest time, from 1850 to 1966, when it was demolished as part of the Market-Mohawk Urban Renewal project. North Market remains, the only one left of four public markets that operated in the city.

The Hartman Hotel is an condominium complex and former hotel and office building in Downtown Columbus, Ohio. The building was completed in 1898 and was listed on the National Register of Historic Places in 2018.The six-story Neoclassical building was designed by the local firm Kremer & Hart. It operated as the Pe-Ru-Na Company headquarters from 1898 to 1902, when it became the Hartman Hotel. The hotel closed in 1921, and the building began to house Ohio governmental agencies. Most of these departed in 1933, though the building maintained offices until 1992. It stood vacant from 1992 to 1999, when it was renovated and restored. Another renovation took place from 2005 to 2008, creating condominiums on much of the building's floor space.

Ohio Police and Fire Memorial Park is a memorial and park commemorating Ohio's police officers and firefighters, in Downtown Columbus, Ohio, United States. The park is north of Town St. just east of Third St. It features a sculpture by Ronald Dewey, engraved bricks, pavers, and benches.

Second Presbyterian Church (also known as Central Presbyterian Church) is a historic church building in Downtown Columbus, Ohio. It was built in 1857 in a Romanesque style and was added to the National Register of Historic Places in 1983. It closed on November, 2011. The site was previously the location of the first public school in Columbus, built in 1826.The building was acquired by Columbus Association for the Performing Arts in 2013, and is being repurposed as a performance venue. CAPA CEO William Conner Jr. said the church building is "acoustically near perfect".

The Zettler Grocery and Hardware building is a historic building in Downtown Columbus, Ohio. It was built c. 1880 and listed on the National Register of Historic Places in 2014. The building was built for the Zettler Grocery Co., founded around 1880 by Louis Zettler. In 1909, the business closed, and it was leased to other groceries, including Kroger's Grocery (the modern day Kroger Company). Zettler Hardware Co. (founded by Zettler in 1886) moved into the space in 1925, occupying it until 1940. The hardware company moved into another space downtown, and has since expanded to several locations around Central Ohio. The business is still owned by the Zettler family, and is the oldest hardware retailer in Columbus. The building at 268 S. 4th St. was owned by the Zettler family and leased to various companies until 2002, when it was sold to an office supply company. The supply company occupied the building until 2012. Since 2015, the building has housed a local pizzeria.

The Stoddart Block is a historic building in Downtown Columbus, Ohio. It was listed on the National Register of Historic Places in 1994. The building was constructed in 1911 and designed by the local firm David Riebel & Sons. It was designed for a large furniture store, the Frohock Furniture Company, which operated there until 1938. A second furniture company, Hadley's Furniture Company, occupied the building until 1962. It then operated as the Children's Hospital's thrift shop, from 1962 to 1990. By 2014, the building held 52 low-income apartments. It was renovated into affordable micro-apartments at this time.The building has five stories. It has a red brick exterior, flat roof, and steel-reinforced concrete structure. It has three bays on its west side and six on its north. A stone panel above the top floor reads "Stoddart 1911". By 1994, the only alterations affected the storefront level.

John F. Wolfe Columbus Commons is a 6-acre (2.4 ha) park and green space in downtown Columbus, Ohio, located on the site of the former Columbus City Center mall. The park features gardens, a performance stage, carousel, interactive playground equipment, and two foodservice buildings. The project was developed by Columbus Downtown Development Corporation (CDDC) and Capitol South Community Urban Redevelopment Corporation (Capitol South). The park opened on May 26, 2011.On May 11, 2017, Columbus Commons was re-dedicated in honor of community leader John F. Wolfe, who died in 2016, and is now known as the John F. Wolfe Columbus Commons.

The United States Carriage Company is a historic building in Downtown Columbus, Ohio. It was listed on the Columbus Register of Historic Properties in 2014 and the National Register of Historic Places in 2015.

The Del Monte Apartments is a historic building in Downtown Columbus, Ohio. It was built in 1902 and was listed on the National Register of Historic Places in 2016. The Romanesque Revival building was designed by Charles W. Bellows, a Columbus resident and nephew of George Bellows, builder of the 1887 Franklin County Courthouse in the city.The building was constructed as a streetcar suburb-type apartment building with six flats on each of its three levels. The building interior was largely altered as it was converted for office use in 1985.

Columbus City Center (known locally as City Center) was a 1,250,000 sq ft (116,000 m2), three-level shopping center in Columbus, Ohio. It was located in the city's downtown, near the Ohio Statehouse, next to the Ohio Theatre, and connected to a Hyatt hotel. The mall had a large parking structure attached that, despite the mall's closure in 2009, is still used extensively by downtown workers. The parking structure has been joined, directly or via bridge respectively, to two 12 story structures, 250 S. High Street (completed in January 2016) and 80 on the Commons (80 East Rich Street), both of which feature lower level office spaces with residential spaces on the upper floors. At the time of its opening, City Center was Central Ohio's largest and most upscale shopping mall. However, a combination of factors soon stripped it of this status.

The Columbus Public School Library was a two-story building in Downtown Columbus, Ohio. It operated as the school library and administrative offices for the Columbus Public School District from 1892 to 1912. The library was established in the former First Methodist Episcopal Church, built in 1853 and extensively renovated for the district's use. The library opened in April 1892 and its ceiling collapsed in September 1912, leading to the building's demolition in 1913.