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BioNTech

2019 initial public offeringsBioNTechBiotechnology companies established in 2008Biotechnology companies of GermanyCOVID-19 vaccine producers
Companies based in MainzCompanies listed on the NasdaqGerman companies established in 2008Medical researchSource attribution
Mainz.BioNTechSE.20200731
Mainz.BioNTechSE.20200731

BioNTech SE ( bee-ON-tek; or bye-ON-tek short for Biopharmaceutical New Technologies) is a German biotechnology company based in Mainz that develops and manufactures active immunotherapies for patient-specific approaches to the treatment of diseases. It develops pharmaceutical candidates based on messenger ribonucleic acid (mRNA) for use as individualized cancer immunotherapies, as vaccines against infectious diseases and as protein replacement therapies for rare diseases, and also engineered cell therapy, novel antibodies and small molecule immunomodulators as treatment options for cancer. The company has developed an mRNA-based human therapeutic for intravenous administration to bring individualized mRNA-based cancer immunotherapy to clinical trials and to establish its own manufacturing process.In 2020, BioNTech, partnering with Pfizer for testing and logistics, developed the RNA vaccine BNT162b2 for preventing COVID-19 infections, which at the time offered a 91% efficacy in preventing confirmed COVID-19 occurring at least 7 days after the second dose of vaccine. On 2 December 2020, temporary HMR authorization was granted by the United Kingdom government for BNT162b2 vaccinations within the United Kingdom. It was the first mRNA vaccine ever authorized. Some days later the vaccine also received an emergency approval in the United States, Canada and Switzerland. On 21 December 2020, the European Commission approved BioNTech/Pfizer's coronavirus vaccine in accordance with the positive recommendation of the European Medicines Agency (EMA).

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BioNTech
An der Goldgrube, Mainz Oberstadt (Oberstadt)

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N 49.9878 ° E 8.2713 °
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An der Goldgrube 12
55131 Mainz, Oberstadt (Oberstadt)
Rhineland-Palatinate, Germany
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Mainz.BioNTechSE.20200731
Mainz.BioNTechSE.20200731
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Osteiner Hof
Osteiner Hof

The Osteiner Hof ("Court of Ostein") is one of several Baroque-era palatial mansions along Schillerplatz square in the German city of Mainz. The mansion, along the southern edge of the square, was built in 1747-1752 by architect-soldier Johann Valentin Thomann for Franz Wolfgang Damian von Ostein, brother of Johann Friedrich Karl von Ostein, who was prince-bishop of Mainz at that time. Characteristic features for this building are the three round protrusions (risalits) at the front entrance and on the two corners. The building is lavishly decorated; for instance, the windows are framed by rococo-style cartouches symbolising the elements of air, earth and water. The classical gods Diana and Mars are shown on the cartouches framing the balcony doors. The von Osteins, a dynasty of counts, were not able to make use of the mansion for very long. After the left bank of the Rhine was occupied by French Revolutionary armies, the mansion was appropriated by the state, and in 1798 it became the seat of a newly created département of France, Mont-Tonnerre. The building continued to be used as a seat of government after the Napoleonic era, even gaining the nickname Gouvernement during the years 1854-1859, while emperor-to-be Wilhelm I was serving as military governor of Mainz. During the early days of the Franco-Prussian War (1870–1871), the Osteiner Hof served as military headquarters of a Prussian field marshal, Prince Frederick Charles of Prussia. In 1914, then-military governor General Hugo von Kathen announced the start of World War I to the Mainz populace from the balcony of the Osteiner Hof. The mansion was destroyed by fire during World War II, but was restored in 1947-1948. From 1958 until 2014, the Osteiner Hof was in use by the Bundeswehr as military headquarters and officers' mess. The Osteiner Hof plays an important part in the local carnival traditions. Every year, on 11 November at 11 past 11, the start of the carnival season is proclaimed from the balcony of the mansion.