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The London Apprentice is a Grade II* listed public house at 62 Church Street, Isleworth, London.The present building dates to the early 18th century, recorded as a licensed inn by 1731. The pub overlooks Isleworth Stairs, established in the reign of Henry VIII for the ferry connecting Richmond Palace with the north bank of the Thames. It was from Isleworth Stairs that the Nine Day Queen, Lady Jane Grey, boarded the Royal Barge on 9 July 1553 to accept the throne as Queen of England, only to be imprisoned in the Tower 9 days later.

All Saints' Church is the oldest parish church in Isleworth in the London Borough of Hounslow in south-west London. Its 14th-century Kentish ragstone tower and foundations are the only pre–20th-century parts to survive. It faces the Thames before Church Street skirts away from the river to pass Syon Park. The parish itself is pre-Norman. A vicar replacing its rector is recorded in 1290 in records associated with Syon Abbey who gave his family £2 and a new robe each year and daily meat and drink at the upper table in the abbey hall, while his servant was to be fed at the grooms' table. The patron of the church became the trustees of St George's Chapel, Windsor, due to the dissolution of the monasteries. By the end of the 17th century, Sir Christopher Wren was approached to draw plans for a new body of a much-dilapidated building. His project was deemed too expensive until 1705, when Sir Orlando Gee (MP), of Syon Hill in the parish, left £500 towards the work in his will; he is commemorated in a marble monument by Francis Bird. This sum, combined with funds raised through subscriptions, ensured that the work took place (with modifications) in 1705–1706. The music theorist Marmaduke Overend served as organist from 1760 to 1790. In 1943 a large fire, started by two boys who a few days later set fire to Holy Trinity Church in Hounslow, led to complete internal reconstruction in lighter materials. The inner body of the present church was built in 1970 by the architect Michael Blee, who designed much of Douai Abbey, and the glazier Keith New; the 15th-century stone tower was retained. The Grade II* listed church won a Civic Trust award in 1973.

The Duke of Northumberland's River or D. O. N. River consists of separate upper and lower artificial watercourses in west London, United Kingdom. The older name Isleworth Mill Stream/River more accurately describes the economic motivation behind its construction. The first section draws water via a sluice from the Colne — a source river which has seven distributaries, many of which are man-made — today an extended distance (to bypass Heathrow Airport) of about 5 miles (8 km) into the Crane; its lower section of about 1.8 miles (2.9 km) draws water from that small river in Whitton, Twickenham and discharges it via neighbouring Isleworth, passing Mill Plat into the tidal Thames. A sluice underneath Mill Plat feeds the main lake in Syon Park.

Isleworth Ait, also known as Isleworth Eyot, is a between 3.5-hectare (8.6-acre) and 9.370-acre (3.792 ha) teardrop-shaped island in the River Thames in England. The long ait is on the Tideway facing Old Isleworth and the towpath alongside the Royal Mid-Surrey Golf Club. These places are in the London Boroughs of Hounslow and Richmond upon Thames. The island faces Heron's Place and a number of commercial buildings.

Isleworth Cemetery is a cemetery in Isleworth, London Borough of Hounslow, in west London, England. The cemetery is classified as full. The last formal burial service took place in the chapel building in the mid 1970s. The chapel and mortuary buildings were closed in the early 1980s. Following a forty year period of neglect, the buildings have recently been extensively refurbished by Hounslow Men's Shed. The chapels now operate as a community workshop as part of the UK Men's shed programme.

West Middlesex University Hospital (WMUH) is an acute NHS hospital in Isleworth, West London, operated by Chelsea and Westminster Hospital NHS Foundation Trust. It is a teaching hospital of Imperial College School of Medicine and a designated academic health science partner (Imperial College Academic Health Sciences Partnership). West Middlesex University Hospital serves patients in the London Boroughs of Hounslow, Richmond upon Thames and Ealing. The hospital has over 400 beds and provides a full range of clinical services including accident and emergency, acute medicine, care of the elderly, surgery and maternity.

The River Crane, a tributary of the River Thames, runs 8.5 miles (13.6 km) in West London, England. It forms the lower course of Yeading Brook. It adjoins or passes through three London boroughs: Hillingdon, Hounslow and Richmond upon Thames, in the historic county of Middlesex. The drainage basin is heavily urbanised but many of the Hayes to Whitton flood-meadows have been conserved, forming a narrow, green vale, opening out to what remains of Hounslow Heath in the centre – a near-continuous belt of semi-natural habitat. At the start of the twentieth century several small sewage works discharged to the river. However these have been consolidated with others into one (Mogden Sewage Treatment Works) which discharges directly to the upper estuary of the Thames (the Tideway). The Crane's form has been greatly altered by river engineering works: over centuries the watercourse has been subject to widening, narrowing, straightening, dredging and bank reinforcement. The greatest of such works has been the two-phase construction of the Duke of Northumberland's River (DNR), a tributary and distributary, to guarantee water power to mills, now demolished, across the south and southeast of Isleworth, which in latter decades worked calico cloth as well as grain. The Lower DNR also waters the grand fish pond inherited from Syon Abbey, which gave way in the dissolution of the monasteries to Syon House and Syon Park. The semi-private park, with its scenic tea room, garden centre and hotel, has a nature reserve zone alongside the Thames. Its lake is still refreshed via sluice and culvert from the Lower DNR's Mill Plat, and thus is supplied by virtue of the Crane from the Colne and the Yeading Brook. The latter means the river system has sources in the London Boroughs of Harrow and Ealing [in Southall as an overflow offtake from the Paddington Arm of the Grand Union Canal].

The King's Observatory (called for many years the Kew Observatory) is a Grade I listed building in Richmond, London. Now a private dwelling, it formerly housed an astronomical and terrestrial magnetic observatory founded by King George III. The architect was Sir William Chambers; his design of the King's Observatory influenced the architecture of two Irish observatories – Armagh Observatory and Dunsink Observatory near Dublin.

Isleworth Town Primary School, founded in 1910, is a mixed community primary school located in Isleworth, London. In a 2023 Ofsted inspection, the school received a good mark, which it has retained since 2012.

Sheen Priory (ancient spelling: Shene, Shean, etc.) in Sheen, now Richmond, London, was a Carthusian monastery founded in 1414 within the royal manor of Sheen, on the south bank of the Thames, upstream and approximately 9 miles southwest of the Palace of Westminster. It was built on a site approximately half a mile to the north of Sheen Palace, which itself also occupied a riverside site, that today lies between Richmond Green and the River Thames. All above-ground traces of the priory have disappeared, yet it is known that the foundations of the priory church lie to the immediate southwest of Kew Observatory, under the fairway of the 14th hole of the Royal Mid-Surrey Golf Course, in Richmond Old Deer Park. It is sometimes incorrectly referred to as Richmond Priory, due to the subsequent renaming of Sheen Manor in 1501.

The Coach and Horses is a Grade II listed public house at London Road, Isleworth, London.It was built in the 18th century, with later alterations. Charles Dickens mentions the pub in his novel Oliver Twist.

The London Butterfly House was a visitor attraction in Brentford, Middlesex, England where the public could view butterflies, birds, reptiles, amphibians, insects, and arachnids. Set in Syon Park, the grounds of Syon House, the facility consisted of three purpose built greenhouses situated overlooking a lake. The facility contained hundreds of the world's most exotic species of butterfly, along with descriptions and illustrations. It also contained a small aviary. The London Butterfly House closed on 28 October 2007, due to the Duke of Northumberland's plans to build a hotel complex on the land. The greenhouses were demolished in November/December 2007 and the 5 star hotel built in their place. The London Syon Park (part of the Hilton Worldwide Waldorf Astoria Hotels and Resorts) opened in March 2011 with conference facilities, restaurants, and a spa.There was a proposal to build a replacement Butterfly House in Gunnersbury Park, but this was rejected.The owners of the London Butterfly House acquired The Butterfly and Wildlife Park in Long Sutton, Lincolnshire, to which the creatures and many of the plants have been re-located. Unfortunately this closed in 2012 due to rising costs and reduced visitor numbers.