Interstate Power Company Building

Upper Main Street Historic District is a nationally recognized historic district located in Dubuque, Iowa, United States. It was listed on the National Register of Historic Places in 2005. At the time of its nomination it consisted of 24 resources, which included 18 contributing buildings, and six non-contributing buildings. In 2011 the boundaries of the district were expanded to include four additional buildings on the west side of the 900 block of Main Street. The district is the northern end of the city's most important commercial street. It is situated on a level terrace above the downtown area, located to the east. The buildings located on the east side of Main Street have exposed foundations along the alley because the grade descends in that direction. For the most part the district is made up of commercial buildings, although there is one house, four rowhouses, and a church. All of the buildings are masonry construction, and they are between one and four stories tall. The bell tower of St. Luke's United Methodist Church (1896) is equivalent to an eight-story building. St. Luke's Church and the Interstate Power Company Building (1894, 1956) are individually listed on the National Register.

Dubuque YMCA Building, also known as the Iowa Inn, is a historic building located in Dubuque, Iowa, United States. Several area churches partnered to form the local YMCA in 1857. It was one of the first chapters formed west of the Mississippi River. Its activities ceased during the American Civil War, and it was reformed in 1866. They rented rooms on Main Street for their activities. Its first modest gymnasium was outfitted in 1884, and it was improved in 1992 when YMCA took over the facilities over the former Dubuque Athletic Club. The local YMCA completed the first section of this facility two years later, with the second section completed in 1916. Often the local YMCA chapters copied or adapted one another's building designs, which gave their facilities an institutional character in form and style. The Romanesque Revival style was popular in Iowa in the 19th century, which is reflected in the 1894 section. In the early 20th century they generally employed the Neoclassical and Commercial styles, and the 1916 wing reflects the Commercial style. YMCA remained here until 1969, when they opened a new joint facility with the YWCA on Dodge Street. This building became the Iowa Inn, which rented rooms to low-income people. MetroPlains Development of St. Paul, Minnesota bought the building in 2000 and renovated it into an apartment building for senior citizens known as the Henry Stout Apartments. It was named for an early supporter of YMCA in Dubuque.The building was listed on the National Register of Historic Places in 2002.

The Town Clock is a large clock that stands in downtown Dubuque, Iowa. The clock has stood over the city for over 140 years. The present clock is the second "Town Clock"; the first collapsed in the 1870s, killing three people. The building on which it originally stood is listed on the National Register of Historic Places, but the clock tower itself is not.

St. Luke's United Methodist Church, also known as St. Luke's Methodist and as St. Luke's United Methodist, is a historic Richardsonian Romanesque-style church located at 1199 Main Street in Dubuque, Iowa. It was individually listed on the National Register of Historic Places in 1998, and as a contributing property in the Upper Main Street Historic District in 2005. It is part of the Iowa Conference of the United Methodist Church. The church has more Tiffany windows than any other church in the state.According to its NRHP nomination, the building is significant for its history in religion in Dubuque, for its Richardsonian Romanesque (unique in Dubuque), and for its Tiffany glass.: 15 

The Security Building, also known as the Stampfer Building, is a historic structure in Dubuque, Iowa, United States. The cream-colored building is associated with the J. F. Stampfer Co. department store.

The Carnegie-Stout Public Library is located in Dubuque, Iowa, United States. The public library had its beginnings with the Young Men's Literary Association, established in 1859, and their book collection was the basis for the library's collection. The books were housed in a variety of buildings over the years. The community applied for a grant from Andrew Carnegie who on January 12, 1901, contributed $71,500 to build the library building. Local businessman Frank D. Stout donated the property, which was worth $20,000, in honor of his father Henry L. Stout. The two-story Bedford stone and brick building was designed by Chicago architects W. G. Williamson and John Spencer. It is considered one of the finest examples of the Classical tradition of Beaux-Arts architecture in Iowa. The main facade is dominated by a Roman Corinthian portico that was modeled after the Pantheon in Rome. Its fluted columns are matched with pilasters on the wall behind. The building was dedicated on October 17, 1902, and it opened three days later. It was individually listed on the National Register of Historic Places in 1975, and it was included as a contributing property in the Jackson Park Historic District in 1986. An addition was added to the east side of the building in 1981.

The Grand Opera House is an opera house located at the corner of 8th and Iowa Streets in Dubuque, Iowa that was built in 1890. It was listed on the National Register of Historic Places in 2002.It was deemed important as a "national treasure". The theatre has the largest of all stages ever in Dubuque, and is Dubuque's only surviving opera house. It is architecturally important as an early Richardsonian Romanesque building in Dubuque and as a salient work of Chicago architect Willoughby James Edbrooke. It is Edbrooke's only surviving opera house, and he used its design in his design portfolio that won him the position of Supervising Architect of the U.S. Treasury Department in 1891. Its design is said to be "representative of Edbrooke's smooth exterior wall interpretation of the Richardsonian Romanesque style." It is also historically important from its association with high-quality theatre in Dubuque during 1890-1928. The theater has been preserved with great historic integrity and, in 2002, was being restored for continuing use in live stage entertainment. Its history is extremely well documented.In 2015 performance events at the theater marked its 125th anniversary.

Dubuque City Hall is located in Dubuque, Iowa, United States. The building was designed by J.N. Moody after Faneuil Hall in Boston and the Fulton Street Market in New York City. Dubuque architect John F. Rague served as the supervising architect during construction. Following a Medieval tradition, the city market was located on the first floor, municipal offices were located on the second floor, and a ballroom for civic events was located on the third floor.The three-story brick structure rests on a raised limestone basement. It features a gable roof with bracketed eaves. Each gable has a circular window. The 11-foot (3.4 m) tall windows are located in bays defined by arches. The building was first occupied in February 1858. Initially, the main floor was divided into stalls. They were converted into additional office space for the city when the market relocated. The third floor ballroom was converted into an archery and pistol range for the police department, a bowling alley, and a horseshoe pitching area. The original cupola, which held a bell and four-faced clock, became deteriorated and was removed from the building in 1954. The bell was placed in the plaza next to city hall. The building was listed on the National Register of Historic Places in 1972. A new cupola was created using the original design, and it was erected in 1990. The bell was returned to the tower at that time.

Roshek Brothers Department Store was a large retail store in downtown Dubuque, Iowa. The company was founded by J.J.and F.H. Roshek. In its prime, Roshek's was the primary shopping destination in Dubuque and was the largest department store in the state of Iowa. The building has been listed on the National Register of Historic Places.

The Dubuque Museum of Art is an art museum in Dubuque, Iowa. The museum is known for its collection of works by Grant Wood. The collections include more than 2,500 works of art housed in the former Statesman Bank building in downtown Dubuque. The museum was founded in 1987, although it evolved out of the Dubuque Art Association which had been operating sporadically since 1874.

The John Bell Block, also known as the German Bank & Trust Building, is a historic building located in Dubuque, Iowa, United States. The three-story brick commercial Italianate building was constructed by local businessman John Bell in 1886. Its location on the north side of the central business district meant that it housed several businesses owned by the city's German immigrant population. Chief among them was the German Trust and Savings Bank. It became a tenant when the building was completed and it remained until it built its own building in 1922. In 1918 anti-German sentiments that resulted from World War I forced the bank to change its name to Union Trust and Savings Bank. It remained in operation until 1932 when a run on its deposits as a result of the Great Depression forced it to fail. Its building was taken over by Dubuque Bank and Trust. Three prominent Dubuque professionals also had offices on the second floor of the building. German-born architect Martin Heer had offices beginning in 1888. He partnered with another German-born architect, Guido Beck, from 1889 to 1895. Beck was noted for his commercial blocks and churches. Contractor Anton Zwack had offices here from 1911 to c. 1965. The building was listed on the National Register of Historic Places in 2002. An early tenant was Baumgartner and Kleih Hardware store

The Ziepprecht Block is a historic building located in Dubuque, Iowa, United States. Completed in 1888, it is a fine example of transitional commercial Italianate architecture. The three-story brick structure features a heavy projecting cornice and rounded pediment from the Italianate, with larger paired windows from the Second Empire style, and three-sided bay windows from the Queen Anne style. It is also one of a small number of double storefront blocks that remain in the downtown area. The building is named for Henry Ziepprecht a German-born druggist who settled in Dubuque in 1856 and died in 1887. His estate paid to have this building constructed on the location of an older building that housed his drug store. Now managed by Joseph Wittmer, the drug store and a confectionery were the first businesses to occupy the storefronts. The upper floors housed apartments. The building was listed on the National Register of Historic Places in 2002.