Pittsburgh Mercantile Company Building

The Samuel F. B. Morse School at 2418 Sarah Street in the South Side Flats neighborhood of Pittsburgh, Pennsylvania, was built in 1874. It was named in honor of Samuel Morse, commonly credited as the inventor of the telegraph. Today, it is an apartment building known as "Morse Gardens". The school originally served an area of German, Scotch-Irish, and Welsh immigrants, who floated a $66,000 bond issue in order to build the school. It was added to the National Register of Historic Places on September 30, 1986.

SouthSide Works is an open-air retail, office, entertainment, and residential complex (often referred to as a lifestyle center) located on the South Side of the city of Pittsburgh, Pennsylvania, U.S. and just across the Monongahela River from the Pittsburgh Technology Center, the University of Pittsburgh and Carnegie Mellon University. The $300 million complex ($441.9 million today) opened in stages between 2002 and 2004 and offers more than 34 acres (140,000 m2) of shops, offices, hotels and apartments, and has a new urbanist design. The site has over 330,000 square feet (30,000 m2) of specialty retail, restaurant, hotel, and apartment space. In addition, the site has 700,000 square feet (70,000 m2) of office space.

J&L Tunnel is a tunnel on CSX Transportation's Pittsburgh Subdivision, at the former location of Jones and Laughlin Steel Company (now the SouthSide Works). The tunnel was used to allow trains on the Pittsburgh and Lake Erie Railroad to bypass the Jones and Laughlin steel mill, by passing under it. Starting in 2011, work was performed, as part of CSX Transportation's National Gateway project, to raise the clearance inside the tunnel, allowing double-stacked container trains to pass through the tunnel.Above the tunnel is a small park called Tunnel Park.

South Shore Riverfront Park is a 3.4-acre park that spans from 25th to 29th streets along the south banks of the Monongahela River upriver from Downtown Pittsburgh, Pennsylvania, United States. The park is situated on the site of the former Jones & Laughlin Steel Mill, and is adjacent to the SouthSide Works retail and residential complex. The park opened to the public in May 2012. It is a parcel of Three Rivers Park, the city's urban waterfront park along its rivers that provides a continuous green trail link between existing and future riverfront destinations. Completed segments of Three Rivers Park include North Shore Riverfront Park, Allegheny Riverfront Park, and Point State Park. The Three Rivers Heritage Trail and Great Allegheny Passage run through South Shore Riverfront Park. It is owned by the Urban Redevelopment Authority of Pittsburgh, with maintenance coordinated by The Soffer Organization and Riverlife.

The Carnegie Library of Pittsburgh – South Side located at 2205 East Carson Street in the South Side Flats neighborhood of Pittsburgh, Pennsylvania, was built in 1909. It was designed by the architectural firm Alden & Harlow, and it was added to the List of Pittsburgh History and Landmarks Foundation Historic Landmarks in 1990.

McGowan Institute for Regenerative Medicine is a medical research institute which is a partnership between the University of Pittsburgh and the University of Pittsburgh Medical Center and is located in Pittsburgh, Pennsylvania, United States.

Pittsburgh Technology Center (PTC) is an office park located in the South Oakland neighborhood of Pittsburgh, Pennsylvania. PTC, on the 48 acre site of a former Jones and Laughlin Steel Mill, is a hub of advanced academic and corporate technology research. More than 1,000 people work on site which has become an attractive location for knowledge workers in Pittsburgh's new economy. The center was budgeted at $56.8 million ($113 million today) during the summer of 1991. The total development cost, including public and private investment, exceeded $104 million. The Pittsburgh Life Sciences Greenhouse operates wet lab space in its Bridgeside Point I business incubator that has been responsible for assisting over 24 companies. The $46.5 million 150,000 Bridgeside Point II began construction in 2007.PTC is considered to be one of the best examples of brownfield redevelopment in the United States.

The Hot Metal Bridge is a truss bridge in Pittsburgh, Pennsylvania, that crosses the Monongahela River. The bridge consists of two parallel spans on a single set of piers: the former Monongahela Connecting Railroad Bridge, built in 1887, on the upstream side and the former Hot Metal Bridge, built in 1900, on the downstream side. The Monongahela Connecting Railroad Bridge carried conventional railroad traffic, while the Hot Metal Bridge connected parts of the J&L Steel mill, carrying crucibles of molten iron from the blast furnaces in ladle transfer cars to the open hearth furnaces on the opposite bank to be converted to steel. During World War II 15% of America's steel making capacity crossed over the Hot Metal Bridge, up to 180 tons per hour. The upstream span was converted to road use after a $14.6 million restoration, and opened by Mayor Tom Murphy with a ceremony honoring former steel workers on June 23, 2000. The bridge connects 2nd Avenue at the Pittsburgh Technology Center in South Oakland with Hot Metal Street (South 29th Street) in the South Side. The downstream span reopened for pedestrian and bicycle use in late 2007 after two years of work. The Great Allegheny Passage hiker/biker trail passes over this bridge as it approaches Pittsburgh's Golden Triangle area. The Pittsburgh History and Landmarks Foundation was responsible for managing the decorative lighting project for the bridge, which was lit with energy-efficient light-emitting diode (LED) and optical fiber technology on June 12, 2008. The Hot Metal Bridge was inducted into the North America Railway Hall of Fame in 2016.

South Side (or "Southside") is an area in Pittsburgh, Pennsylvania, United States, located along the Monongahela River across from Downtown Pittsburgh. The South Side is officially divided into two neighborhoods, South Side Flats and South Side Slopes. Both the Flats and the Slopes are represented on Pittsburgh City Council by Bruce Kraus. The business district stretches along East Carson Street, which is home to many small shops, restaurants and bars. In 2006, more than 80 bars and pubs operated in the South Side Flats. The neighborhood has an urban fabric with rowhouses. The South Side is well-connected with public transit. Its proximity and public transit connections also have attracted professionals who work downtown. Pittsburgh Fire Station #24 is located on Mary Street in the neighborhood.

Located on the Duquesne Brewing Company building in Pittsburgh, Pennsylvania, the Duquesne Brewery Clock was the largest single-face clock in the world when it was installed in 1933. Over the years its face has been used to advertise numerous brands, beginning with Coca-Cola.

The Entertainment Technology Center (ETC) is a department at Carnegie Mellon University in Pittsburgh, Pennsylvania, United States. It is located at the Pittsburgh Technology Center. The ETC offers a two-year Masters of Entertainment Technology (MET) degree, jointly conferred by Carnegie Mellon University's College of Fine Arts and School of Computer Science. Students enrolled in the ETC learn interdisciplinary skills in design, art and technology, and are prepared for environments where artists and technologists work hand-in-hand, such as theme parks, interactive museum exhibits, website design and development, and the creation of video games.

The Brew House Association is an artist collective established in 1991 in the South Side Flats neighborhood of Pittsburgh, Pennsylvania. It is located at Mary and 21st Streets in a multi-story building that once housed the Duquesne Brewing Company. The lower floors of the building have been converted to gallery and theater space, including SPACE 101, an alternative exhibit gallery founded by the Brew House Association in 1994, while the upper floors have become studio and living areas for resident artists, and shared workshops for welding and pottery. The Brew House and the abandoned industrial lots around it have been the site of performance art, theatre and sculpture exhibits. They formerly rented studio space and hosted a residency program for visual artists before issues with building code violations forced them to temporarily close their doors in 2009.