Laocoön and His Sons

The Cortile del Belvedere (Belvedere Courtyard or Belvedere Court) was a major architectural work of the High Renaissance at the Vatican Palace in Rome. Designed by Donato Bramante from 1505 onward, its concept and details reverberated in courtyard design, formalized piazzas and garden plans throughout Western Europe. Conceived as a single enclosed space, the long Belvedere court connected the Vatican Palace with the Villa Belvedere in a series of terraces connected by stairs, and was contained on its sides by narrow wings. Bramante did not see the work completed, and before the end of the sixteenth century it had been irretrievably altered by a building across the court, dividing it into two separate courtyards.

The Gallery of Maps (Italian: Galleria delle carte geografiche) is a gallery located on the west side of the Belvedere Courtyard in the Vatican containing a series of painted topographical maps of Italy based on drawings by friar and geographer Ignazio Danti.The gallery was commissioned in 1580 by Pope Gregory XIII as part of other artistic works commissioned by the Pope to decorate the Vatican. It took Danti three years (1580–1583) to complete the 40 panels of the 120 m long gallery.

The Vatican Apostolic Archive (Latin: Archivum Apostolicum Vaticanum; Italian: Archivio Apostolico Vaticano), formerly known as the Vatican Secret Archive, is the central repository in the Vatican City of all acts promulgated by the Holy See. The pope, as the sovereign of Vatican City, owns the material held in the archive until his death or resignation, with ownership passing to his successor. The archive also contains state papers, correspondence, account books, and many other documents that the church has accumulated over the centuries. Pope Paul V separated the Secret Archive from the Vatican Library, where scholars had some very limited access, and the archive remained closed to outsiders until the late 19th century, when Pope Leo XIII opened the archive to researchers, more than a thousand of whom now examine some of its documents each year.

Minuscule 151 (in the Gregory-Aland numbering), A17 (Soden), is a Greek minuscule manuscript of the New Testament, on parchment leaves. Palaeographically it has been assigned to the 10th century. The manuscript has complex contents. It has marginalia.

Porta Cavalleggeri was one of the gates of the Leonine Wall in Rome (Italy).

The Vatican Apostolic Library (Latin: Bibliotheca Apostolica Vaticana, Italian: Biblioteca Apostolica Vaticana), more commonly known as the Vatican Library or informally as the Vat, is the library of the Holy See, located in Vatican City. It was formally established in 1475, although it is much older—it is one of the oldest libraries in the world and contains one of the most significant collections of historical texts. It has 75,000 codices from throughout history, as well as 1.1 million printed books, which include some 8,500 incunabula.The Vatican Library is a research library for history, law, philosophy, science, and theology. The Vatican Library is open to anyone who can document their qualifications and research needs. Photocopies for private study of pages from books published between 1801 and 1990 can be requested in person or by mail. Pope Nicholas V (1447–1455) envisioned a new Rome with extensive public works to lure pilgrims and scholars to the city to begin its transformation. Nicolas wanted to create a "public library" for Rome that was meant to be seen as an institution for humanist scholarship. His death prevented him from carrying out his plan, but his successor Pope Sixtus IV (1471–1484) established what is now known as the Vatican Library. In March 2014, the Vatican Library began an initial four-year project of digitising its collection of manuscripts, to be made available online. The Vatican Apostolic Archive was separated from the library at the beginning of the 17th century; it contains another 150,000 items.

The Niccoline Chapel (Italian: Cappella Niccolina) is a chapel in the Apostolic Palace in Vatican City. It is especially notable for its fresco paintings by Fra Angelico (1447–1451) and his assistants, who may have executed much of the actual work. The name is derived from its patron, Pope Nicholas V, who had it built for use as his private chapel. The chapel is located in the Tower of Innocent III, in the most ancient part of the Apostolic Palace. The walls were decorated by Fra Angelico with images of two of the earliest Christian martyrs; the upper level has Episodes from the Life of St. Stephen, and the lower one Scenes from the life of St. Laurence. The vault is painted blue, decorated with stars, and features figures of the Four Evangelists in the corners. The pilasters are decorated with the eight Doctors of the Church. The chapel is not included in the usual tourist visit, but can be seen by special pre-booked groups.

The Borgia Apartments are a suite of rooms in the Apostolic Palace in the Vatican, adapted for personal use by Pope Alexander VI (Rodrigo de Borja). In the late 15th century, he commissioned the Italian painter Bernardino di Betto (Pinturicchio) and his studio to decorate them with frescoes.The paintings and frescoes, which were executed between 1492 and 1494, drew on a complex iconographic program that used themes from medieval encyclopedias, adding an eschatological layer of meaning and celebrating the supposedly divine origins of the Borgias. Five of the six apartments include frescoes painted in the vault. The upper register of the vaults contain paintings, while the lower registers are decorated with tapestries and gold. Recent cleaning of Pinturicchio's fresco The Resurrection has revealed a scene believed to be the earliest known European depiction of Native Americans, painted just two years after Christopher Columbus returned from the New World.The Borgia Apartments includes six rooms: Room of the Sibyls, Room of the Creed, Room of the Liberal Arts, Room of the Saints, Room of Mysteries, and Room of Pontiffs. The Room of Sibyls and the Room of Creed include frescoes of the Old Testament prophets and sibyls. These room also pay homage to the planets. In the Room of Liberal Arts, Pinturicchio has represented the liberal arts as female figures through his frescoes in the vault. The Room of Saints consists of frescoes detailing the lives of seven notable saints, including Barbara, Catherine, Anthony, Paul, Susanna, and Elizabeth. Pinturicchio's last room, the Room of Mysteries, contains frescoes with New Testament subject matter, including the Nativity, Ascension, Adoration of the Magi, and other scenes.The Room of the Pontiffs was erected before all the other buildings, between 1277 and 1280. Built between 1447 and 1455, the Room of the Liberal Arts, Saints, and Mysteries were referred to as "secret rooms" by Pope Alexander VI's master of ceremonies, Johannes Burchard. As of 2019, the suite was open to tourists.

The Collection of Modern and Contemporary Art is a collection of paintings, graphic art and sculptures in the Vatican Museums. It occupies 55 rooms: the Borgia Apartment (apartment of Pope Alexander VI) on the first floor of the Apostolic Palace, the two floors of the Salette Borgia, a series of rooms below the Sistine Chapel, and a series of rooms on the ground floor. Approximately 250 artists created over 500 pieces that are displayed in the Borgia Apartments. The Collection was officially introduced to the public on June 23, 1973.A permanent contemporary art gallery was installed on the premises in November 2021.

The Gregorian Tower (Italian: Torre Gregoriana) or Tower of the Winds (Italian: Torre dei Venti) is a square tower and early modern observatory located above the Gallery of Maps, which connects the Villa Belvedere with the Apostolic Palace in Vatican City. The tower was built between 1578 and 1580 to a design by the Bolognese architect Ottaviano Mascherino (who was credited with building the Apostolic Palace) mainly to promote the study of astronomy for the Gregorian Calendar Reform which was commissioned by Pope Gregory XIII and promulgated in 1582. It was then also known as the Tower of Winds. The tower was also called "Specola Astronomica Vaticana", a reference to the Vatican Observatory. Four stages of progressive development have occurred since it was first established. The tower was an edifice of great value for astronomical observations made using a sundial as they provided essential confirmation of the need to reform the Julian calendar.

The Sistine Chapel ceiling (Italian: Soffitto della Cappella Sistina), painted in fresco by Michelangelo between 1508 and 1512, is a cornerstone work of High Renaissance art. The Sistine Chapel is the large papal chapel built within the Vatican between 1477 and 1480 by Pope Sixtus IV, for whom the chapel is named. The ceiling was painted at the commission of Pope Julius II. The ceiling's various painted elements form part of a larger scheme of decoration within the chapel. Prior to Michelangelo's contribution, the walls were painted by several leading artists of the late 15th century including Sandro Botticelli, Domenico Ghirlandaio, and Pietro Perugino. After the ceiling was painted, Raphael created a set of large tapestries (1515–1516) to cover the lower portion of the wall. Michelangelo returned to the chapel to create The Last Judgment, a large wall fresco situated behind the altar. The chapel's decoration illustrates much of the doctrine of the Catholic Church, serving as the location for papal conclaves and many other important services.Central to the ceiling decoration are nine scenes from the Book of Genesis, including The Creation of Adam. The complex design includes several sets of figures, some clothed and some nude, allowing Michelangelo to demonstrate his skill in depicting the human figure in a variety of poses. The ceiling was immediately well-received and imitated by other artists, continuing to the present. It has been restored several times, most recently from 1980-94.

The conservation-restoration of the frescoes of the Sistine Chapel was one of the most significant conservation-restorations of the 20th century. The Sistine Chapel was built by Pope Sixtus IV within the Vatican immediately to the north of St. Peter's Basilica and completed in about 1481. Its walls were decorated by a number of Renaissance painters who were among the most highly regarded artists of late 15th century Italy, including Ghirlandaio, Perugino, and Botticelli. The Chapel was further enhanced under Pope Julius II by the painting of the ceiling by Michelangelo between 1508 and 1512 and by the painting of the Last Judgment, commissioned by Pope Clement VII and completed in 1541, again by Michelangelo. The tapestries on the lowest tier, today best known from the Raphael Cartoons (painted designs) of 1515–16, completed the ensemble. Together the paintings make up the greatest pictorial scheme of the Renaissance. Individually, some of Michelangelo's paintings on the ceiling are among the most notable works of Western art ever created. The frescoes of the Sistine Chapel and in particular the ceiling and accompanying lunettes by Michelangelo have been subject to a number of restorations, the most recent taking place between 1980 and 1994. This most recent restoration had a profound effect on art lovers and historians, as colours and details that had not been seen for centuries were revealed. It has been claimed that as a result "Every book on Michelangelo will have to be rewritten". Others, such as the art historian James Beck of ArtWatch International, have been extremely critical of the restoration, saying that the restorers have not realised the true intentions of the artist. This is the subject of continuing debate.