Sampaloc Church

The National University (NU), colloquially National U, is a private non–sectarian coeducational university located in Sampaloc, Manila, Philippines. The founder of the university, Mariano F. Jhocson Sr., established the institution on August 1, 1900, as Colegio Filipino in Quiapo, Manila. It is considered as the first private nonsectarian and coeducational institution in the Philippines and also, the first university to use English as its medium of instruction, replacing Spanish.With its main campus in Sampaloc, Manila, the university has been expanding by setting secondary campuses. Other campuses of NU includes: NU Laguna (Sports Academy), NU Fairview, NU Mall of Asia (College of Dentistry), NU Baliwag, NU Dasmariñas, and NU Lipa. Approved by the Department Public Instruction on June 17, 1921, the university received its university status, changing the name from National Academy to National University. Senator Camilo Osías, two-time Senate President of the Philippines, served as the first University President (1921-1936). The current university president is Renato C. Ermita, Jr. (2008–present) and its current majority owner is the SM Group. NU is one of the pioneer members of National Collegiate Athletic Association- Philippines (NCAA) and the University Athletic Association of the Philippines (UAAP), and also a pioneer member of the Philippine Association of Colleges and Universities (PACU). Its international affiliations and memberships include the Association of Southeast Asian Institutions of Higher Learning (ASAHIL) and the International Association of Universities (IAU).

Legarda station is an elevated Manila Light Rail Transit (LRT) station situated on Line 2. The station is located in Sampaloc in Manila and is named after Legarda Street, where the station sits above it. The street in turn is named after Benito Legarda, a Filipino legislator.The station is the second station for trains headed to Antipolo and the twelfth station for trains headed to Recto.

The University of Manila (UM) (Filipino: Ang Pamantasan ng Maynila), is a private, non-sectarian coeducational basic and higher education institution in the heart of Sampaloc District in Manila, Philippines. It was founded on October 5, 1913 as the Instituto de Manila, by Apolinario G. de los Santos, Mariano V. de los Santos, Maria de los Santos, Buenaventura J. Bello and Antonio Rivero. The first three were siblings. They named their school Instituto de Manila, after the city of Manila and Apolinario G. de los Santos was elected as the first director of the school. The University was first situated in Binondo and offered primary and secondary education. It then moved to Sampaloc, Manila.

Legarda Street is a short street located in Sampaloc district in Manila, Philippines. It crosses through the eastern section of the University Belt area in a generally east–west orientation between the Nagtahan Interchange and the intersection with Nepomuceno Street in Quiapo. It is served by Legarda station of LRT Line 2. The street was named after Filipino legislator and resident commissioner to the United States, Benito Legarda y Tuason. Historically, its section in Sampaloc was formerly called Calle Alix (after a Real Audiencia of Manila magistrate of the 1860s, José María Alix y Bonache), while its section in Quiapo was formerly called Plaza Santa Ana and Calle Concordia, respectively.

The Mendiola massacre was an incident that took place in Mendiola Street, San Miguel, Manila, Philippines on January 22, 1987, in which state security forces under President Corazon Aquino violently dispersed a farmers' march to Malacañang Palace in protest for the lack of government action on land reform. Calls for just and comprehensive land reforms to President Aquino were unheeded. The turbulent turn of events sparked rallies and demonstrations taken part by farmers, workers, and students protesting the injustice. According to reports of survivors, riot personnel disguised as civilians opened fire on unarmed protesters killing at least 12 and injuring 51 protesters.

San Beda University (Filipino: Unibersidad ng San Beda) is a private Catholic coeducational basic and higher education institution run by the Order of Saint Benedict in San Miguel, Manila, Philippines. It was founded by the Benedictines in 1901. Its main campus which provides tertiary education is situated in Mendiola, San Miguel, Manila. It has a satellite campus that provides elementary and high school education in Taytay, Rizal.San Beda was established in 1901 by monks of the Ordo Sancti Benedicti (OSB) or Order of St. Benedict, also known as the Benedictines. Its founder, St. Benedict, is acclaimed as the "Father of Western Monasticism" and the "Patron of Europe". From its inception, the school was dedicated to the cause of Catholic education and the formation of Christians committed to excellence and service of God and country. It is attached to the Abbey of Our Lady of Montserrat, founded from the Abbey of Montserrat in Cataluña, Spain. San Beda started as an all-boys grade school in Manila and given the name El Colegio de San Beda. It has since expanded to a full university with both undergraduate and post-graduate degree programs. The institution was given university status on February 6, 2018, making it the only Benedictine university found in the Asia-Pacific region.

Arellano University (AU) is a private, coeducational, nonsectarian university located in Manila, the Philippines. It was founded in 1938 as a law school by Florentino Cayco Sr., the first Filipino Undersecretary of Public Instruction. The university was named after Cayetano Arellano, the first Chief Justice of the Supreme Court of the Philippines. It operates seven campuses located throughout Metro Manila and the main campus is located along Legarda Street, Sampaloc, Manila. The Arellano University School of Law is autonomous and managed by the Arellano Law Foundation. Its athletic team, the Arellano University Chiefs, is a member of the National Collegiate Athletic Association since 2009.

The Abbey of Our Lady of Montserrat, or Manila Abbey, is a Benedictine men's monastery located on Mendiola Street in Manila, the Philippines. The monastery was founded by monks from Spain in 1895, in the final years of Spanish colonial era in the Philippines and is dedicated to Our Lady of Montserrat. The resident monks, which belong to the Philippine Pro-Province of the Subiaco Cassinese Congregation (a part of the Benedictine Confederation) also operate San Beda University on the abbey's grounds.

The University of the East (Filipino: Pamantasan ng Silangan), also known as UE, is a private university located in Manila, Philippines. Founded in 1946, business tycoon Lucio Tan acquired the university in 1990. UE was once labeled as the "largest university in Asia" when its enrollment in the past reached over 65,000 students.The Commission on Higher Education (CHED) granted UE autonomous status and recognized 2 of its programs as Center of Excellence and 1 program as Center of Development. UE offers degree programs from basic education to graduate studies. UE has two other campuses, one in Caloocan, and its medical school, the UE Ramon Magsaysay Memorial Medical Center located in Aurora Blvd., Dona Imelda, Quezon City.

Centro Escolar University (Tagalog: Pamantasang Centro Escolar) also referred to by its acronym CEU is a private non-sectarian higher education institution in San Miguel Manila, Philippines. It was founded in 1907 by Librada Avelino and Carmen de Luna as the Centro Escolar de Señoritas. CEU has six campuses: the main campus, Mendiola; the Malolos campus; the Las Piñas campus; the Cebu City campus; and the Makati campuses (Gil Puyat and Legaspi Village campuses). More than 50 academic programs are offered.CEU is accredited by the Federation of Accrediting Agencies of the Philippines and the Philippine Association of Colleges and Universities' Commission on Accreditation (as a Level IV school), and has full autonomous status from the Commission on Higher Education (CHED). It is certified by the Institute of Corporate Directors, Department of Trade and Industry, SGS S.A., Arthram International Organization for Standardization, and the ASEAN University Network. In 2022, CEU was awarded with the Safety Seal from the Department of the Interior and Local Government, for meeting minimum public health standards following the COVID-19 pandemic shutdowns.

Santa Catalina College is a Roman Catholic, private institution that serves coeducational basic and higher education administered by the Congregation of the Dominican Sisters of St. Catherine of Siena, a religious congregation affiliated with the Dominican Order located in Sampaloc, Manila. It was originally established by the Siena Sisters in 1706.

The University of the East College of Law or UE Law is the law school of the University of the East, a private, non-sectarian university in Manila, Philippines.