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Blackfriars was a short-lived railway station on the South Eastern Railway (SER) line, in the parish of Southwark Christchurch, between Charing Cross and London Bridge. It was opened in 1864 with the name Blackfriars but closed less than five years later when it was replaced by the station now called Waterloo East (originally named Waterloo). In 1886 the London, Chatham and Dover Railway (LCDR) opened a station on the north bank of the river called St. Paul's – this was renamed Blackfriars in 1937. The former entrance to the South Eastern Railway Blackfriars station under the railway bridge on Blackfriars Road itself is still clearly visible. In 2005 the bricked-up former street-level entrance and original wording were restored. At track level, widening of the viaduct on its north side is the only indication of its site. In July 2009 planning permission was granted for a café to be built over the entranceway to the station.

The Surrey Chapel (1783–1881) was an independent Methodist and Congregational church established in Blackfriars Road, Southwark, London on 8 June 1783 by the Rev. Rowland Hill. His work was continued in 1833 by the Congregational pastor Rev. James Sherman, and in 1854 by Rev. Newman Hall. The chapel's design attracted great interest, being circular in plan with a domed roof. When built it was set in open fields, but within a few years it became a new industrial area with a vast population characterised by great poverty amidst pockets of wealth. Recently the site itself has been redeveloped as an office block (currently occupied by the London Development Agency), and Southwark Underground Station has been built opposite.

Nelson Square is a garden square located close to Southwark tube station in the London Borough of Southwark. It was laid out around 1807 as upmarket terraced housing and named after Admiral Horatio Nelson whose death during his victory at the Battle of Trafalgar in 1805 made him a national hero. It runs off Blackfriars Road to the west andUnion Street to the north, while Great Suffolk Street is located a little to the east. The railway running towards Blackfriars Station passes near the eastern end of the square on a viaduct. The square was developed on land owned by Sir Francis Wood, 2nd Baronet, and was most likely entirely designed by the architect Samuel Pepys Cockerell. The poet Percy Bysshe Shelley and his wife Mary Shelley lodged at 26 Nelson Square, which was later commemorated by a blue plaque until a German bombing raid in the Second World War destroyed the building. In 1884 the charitable Blackfriars Settlement was established in the square, at the home of Helen Gladstone. It moved to nearby Great Suffolk Street in 2010. Other notable residents have included Thomas Barnes, the editor of The Times, and the surgeon Charles Aldis.

Southwark is a London Underground station in the London Borough of Southwark at the corner of Blackfriars Road and The Cut. It is between Waterloo and London Bridge stations on the Jubilee line, and is in Travelcard Zone 1. It was opened on 20 November 1999 as part of the Jubilee Line Extension. The station is somewhat west of historic Southwark, which is served by Borough and London Bridge stations. Its entrance is across the road from the disused Blackfriars Road railway station. The original plan for the Extension did not include a station between those at Waterloo and London Bridge; Southwark station was added after lobbying by the local council, it is in fact sited right next to the borough's boundary with Lambeth at Joane Street. Although it is close to Waterloo, not near the Bankside attractions it was intended to serve, and its only National Rail interchange is to London Waterloo East main line station; the passenger usage matches those of other minor central stations. It does however get over twice the traffic of nearby Borough station, and around three times that of Lambeth North.

The Union Theatre is a fringe theatre situated in the borough of Southwark in London, England. It was established in 1998 by Sasha Regan, and has a reputation for staging musicals.

Blackfriars Road is a road in Southwark, SE1. It runs between St George's Circus at the southern end and Blackfriars Bridge over the River Thames at the northern end, leading to the City of London. Halfway up on the west side is Southwark Underground station, on the corner with The Cut. Opposite is Palestra, a large new office building which houses the Surface transport division of Transport for London, which was formerly the headquarters of the London Development Agency. The road forms part of the A201. The road adjoins Stamford Street and Southwark Street at the northern end. Originally known as Surrey Street, the road was built in the 1760s as the south approach to Blackfriars Bridge, and was laid out by the bridge surveyor, Robert Mylne.From 2010 a number of major development schemes have transformed Blackfriars Road from the bridge to the south at St George's Circus and new buildings have replaced the post World War II offices with residential and hotel accommodation along its length especially at the junction with Stamford Street where major high rises have been erected.

Southwark College is a further education college located in the London Borough of Southwark. The college at one time had seven sites; it is now based at a building on The Cut, opposite Southwark tube station. The college has been part of Newcastle College Group since 2017.

The Africa Centre, London was founded in 1964 at 38 King Street, Covent Garden, where over the years it held many art exhibitions, conferences, lectures, and a variety of cultural events, as well as housing a gallery, meeting halls, restaurant, bar and bookshop. The Africa Centre closed its original venue in 2013, and now has a permanent home at 66 Great Suffolk Street, Southwark. It is a registered charity.

Union Street Café is a restaurant, owned by chef Gordon Ramsay, in Southwark, London. It was the first of Ramsay's restaurants to be opened without the involvement of Chris Hutchinson, and at one point was backed by footballer David Beckham. The Café serves Mediterranean cuisine, with mostly Italian dishes. The head chef, Davide Degiovanni, designs the menu, which is changed daily. Before the Café was opened, it received more than 10,000 booking requests, with seating filled to the end of the year. Food critics' reviews have been mixed, with differing opinions of the veal saltimbocca but agreement in dislike of a dish of octopus, borlotti bean, and 'nduja sausage.

Christ Church, Southwark, is a church of the Anglican denomination situated on the west side of Blackfriars Road, London. At the time of the foundation there was no bridge at Blackfriars and so no major road connecting the area to the south or to the City. The current church was built in 1958, following total destruction of the previous building in 1941, during the London Blitz. It has been Grade II listed since 2010.

Christchurch was a civil parish in the metropolitan area of London, England. It was located south of the River Thames straddling either side of Blackfriars Road. It originated as the manor of Paris Garden in the parish of St Margaret, Southwark. The parish of St Margaret was replaced by St Saviour in 1541 and then in 1670 the area was split off as a parish in its own right when Christ Church was constructed. It was prone to flooding and was not heavily built upon until after 1809. In 1855 the parish was included in the metropolitan area of London where local government was reformed. The parish was united with St Saviour to form part of the St Saviour's District. When the district was abolished in 1900 the parish became part of the Metropolitan Borough of Southwark. It was abolished as a civil parish in 1930. The area now forms the northwestern part of the London Borough of Southwark.

Poured Lines is a 2006 painting by the British painter Ian Davenport. It is the largest painting to be publicly displayed outdoors in the United Kingdom. It is situated under the rail bridge at the western end of Southwark Street in London SE1.